Literature DB >> 23942741

[Novel preclinical models and biomarkers for prostate cancer].

N Korzeniewski1, M Tapia-Laliena, Y Tolstov, S Pahernik, B Hadaschik, M Hohenfellner, S Duensing.   

Abstract

The ultimate goal of a personalized approach to prostate cancer patient management relies on two prerequisites: the development of preclinical but clinically relevant model systems and robust prognostic and predictive biomarkers. The past several years have shown significant progress towards these two prerequisites which will be highlighted in this review using some notable examples.

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Year:  2013        PMID： 23942741     DOI： 10.1007/s00120-013-3310-6

Source DB:  PubMed          Journal:  Urologe A        ISSN： 0340-2592            Impact factor:   0.639


  17 in total

1.  Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer.

Authors:  Joachim Weischenfeldt; Ronald Simon; Lars Feuerbach; Karin Schlangen; Dieter Weichenhan; Sarah Minner; Daniela Wuttig; Hans-Jörg Warnatz; Henning Stehr; Tobias Rausch; Natalie Jäger; Lei Gu; Olga Bogatyrova; Adrian M Stütz; Rainer Claus; Jürgen Eils; Roland Eils; Clarissa Gerhäuser; Po-Hsien Huang; Barbara Hutter; Rolf Kabbe; Christian Lawerenz; Sylwester Radomski; Cynthia C Bartholomae; Maria Fälth; Stephan Gade; Manfred Schmidt; Nina Amschler; Thomas Haß; Rami Galal; Jovisa Gjoni; Ruprecht Kuner; Constance Baer; Sawinee Masser; Christof von Kalle; Thomas Zichner; Vladimir Benes; Benjamin Raeder; Malte Mader; Vyacheslav Amstislavskiy; Meryem Avci; Hans Lehrach; Dmitri Parkhomchuk; Marc Sultan; Lia Burkhardt; Markus Graefen; Hartwig Huland; Martina Kluth; Antje Krohn; Hüseyin Sirma; Laura Stumm; Stefan Steurer; Katharina Grupp; Holger Sültmann; Guido Sauter; Christoph Plass; Benedikt Brors; Marie-Laure Yaspo; Jan O Korbel; Thorsten Schlomm
Journal:  Cancer Cell       Date:  2013-02-11       Impact factor: 31.743

2.  Integrative genomic profiling of human prostate cancer.

Authors:  Barry S Taylor; Nikolaus Schultz; Haley Hieronymus; Anuradha Gopalan; Yonghong Xiao; Brett S Carver; Vivek K Arora; Poorvi Kaushik; Ethan Cerami; Boris Reva; Yevgeniy Antipin; Nicholas Mitsiades; Thomas Landers; Igor Dolgalev; John E Major; Manda Wilson; Nicholas D Socci; Alex E Lash; Adriana Heguy; James A Eastham; Howard I Scher; Victor E Reuter; Peter T Scardino; Chris Sander; Charles L Sawyers; William L Gerald
Journal:  Cancer Cell       Date:  2010-06-24       Impact factor: 31.743

3.  Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer.

Authors:  Christopher E Barbieri; Sylvan C Baca; Michael S Lawrence; Francesca Demichelis; Mirjam Blattner; Jean-Philippe Theurillat; Thomas A White; Petar Stojanov; Eliezer Van Allen; Nicolas Stransky; Elizabeth Nickerson; Sung-Suk Chae; Gunther Boysen; Daniel Auclair; Robert C Onofrio; Kyung Park; Naoki Kitabayashi; Theresa Y MacDonald; Karen Sheikh; Terry Vuong; Candace Guiducci; Kristian Cibulskis; Andrey Sivachenko; Scott L Carter; Gordon Saksena; Douglas Voet; Wasay M Hussain; Alex H Ramos; Wendy Winckler; Michelle C Redman; Kristin Ardlie; Ashutosh K Tewari; Juan Miguel Mosquera; Niels Rupp; Peter J Wild; Holger Moch; Colm Morrissey; Peter S Nelson; Philip W Kantoff; Stacey B Gabriel; Todd R Golub; Matthew Meyerson; Eric S Lander; Gad Getz; Mark A Rubin; Levi A Garraway
Journal:  Nat Genet       Date:  2012-05-20       Impact factor: 38.330

4.  Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation.

Authors:  Stefan T Börno; Axel Fischer; Martin Kerick; Maria Fälth; Mark Laible; Jan C Brase; Ruprecht Kuner; Andreas Dahl; Christina Grimm; Behnam Sayanjali; Melanie Isau; Christina Röhr; Andrea Wunderlich; Bernd Timmermann; Rainer Claus; Christoph Plass; Markus Graefen; Ronald Simon; Francesca Demichelis; Mark A Rubin; Guido Sauter; Thorsten Schlomm; Holger Sültmann; Hans Lehrach; Michal R Schweiger
Journal:  Cancer Discov       Date:  2012-08-28       Impact factor: 39.397

5.  Modeling a lethal prostate cancer variant with small-cell carcinoma features.

Authors:  Vassiliki Tzelepi; Jiexin Zhang; Jing-Fang Lu; Brittany Kleb; Guanglin Wu; Xinhai Wan; Anh Hoang; Eleni Efstathiou; Kanishka Sircar; Nora M Navone; Patricia Troncoso; Shoudan Liang; Christopher J Logothetis; Sankar N Maity; Ana M Aparicio
Journal:  Clin Cancer Res       Date:  2011-12-12       Impact factor: 12.531

6.  Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms.

Authors:  Zhi Gang Li; Paul Mathew; Jun Yang; Michael W Starbuck; Amado J Zurita; Jie Liu; Charles Sikes; Asha S Multani; Eleni Efstathiou; Adriana Lopez; Jing Wang; Tina V Fanning; Victor G Prieto; Vikas Kundra; Elba S Vazquez; Patricia Troncoso; Austin K Raymond; Christopher J Logothetis; Sue-Hwa Lin; Sankar Maity; Nora M Navone
Journal:  J Clin Invest       Date:  2008-08       Impact factor: 14.808

7.  Poly-gene fusion transcripts and chromothripsis in prostate cancer.

Authors:  Chunxiao Wu; Alexander W Wyatt; Andrew McPherson; Dong Lin; Brian J McConeghy; Fan Mo; Robert Shukin; Anna V Lapuk; Steven J M Jones; Yongjun Zhao; Marco A Marra; Martin E Gleave; Stanislav V Volik; Yuzhuo Wang; S Cenk Sahinalp; Colin C Collins
Journal:  Genes Chromosomes Cancer       Date:  2012-08-25       Impact factor: 5.006

8.  The androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man.

Authors:  Naomi L Sharma; Charlie E Massie; Antonio Ramos-Montoya; Vincent Zecchini; Helen E Scott; Alastair D Lamb; Stewart MacArthur; Rory Stark; Anne Y Warren; Ian G Mills; David E Neal
Journal:  Cancer Cell       Date:  2012-12-20       Impact factor: 31.743

9.  Distinct ERG rearrangement prevalence in prostate cancer: higher frequency in young age and in low PSA prostate cancer.

Authors:  G Schaefer; J-M Mosquera; R Ramoner; K Park; A Romanel; E Steiner; W Horninger; J Bektic; M Ladurner-Rennau; M A Rubin; F Demichelis; H Klocker
Journal:  Prostate Cancer Prostatic Dis       Date:  2013-02-05       Impact factor: 5.554

10.  A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer.

Authors:  Andrea Lunardi; Ugo Ala; Mirjam T Epping; Leonardo Salmena; John G Clohessy; Kaitlyn A Webster; Guocan Wang; Roberta Mazzucchelli; Maristella Bianconi; Edward C Stack; Rosina Lis; Akash Patnaik; Lewis C Cantley; Glenn Bubley; Carlos Cordon-Cardo; William L Gerald; Rodolfo Montironi; Sabina Signoretti; Massimo Loda; Caterina Nardella; Pier Paolo Pandolfi
Journal:  Nat Genet       Date:  2013-06-02       Impact factor: 38.330
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