OBJECTIVES: The aim of this study was to assess variation of qualitative and quantitative PET/CT image quality parameters with acquisition time, injection activity and body mass for a representative group of adults undergoing whole-body PET/CT imaging. METHODS: PET scan data from sixty patients were reconstructed with a scan time of 1, 2 and 3 min/bed position. These images were visually scored and three quantitative parameters were calculated: noise equivalent counts per axial length (NECpatient), noise equivalent count density (NECdensity) and liver signal to noise ratio (liver SNR). The ability of the three quantitative parameters to discriminate qualitative image quality was assessed using ROC analysis. RESULTS: The quantitative parameters were shown to discriminate images of good/excellent quality from those of poorer image quality with a high degree of accuracy (ROC area >0.9); further, NECpatient had significantly higher discrimination than either NECdensity or liver SNR (ROC area = 0.97). CONCLUSIONS: NECpatient, NECdensity and liver SNR all have high discrimination for qualitatively assessed PET image quality. NECpatient in particular is an effective objective indicator of patient image quality, which will help to assess and standardise scan protocols for purposes such as multi-centre research trials.
OBJECTIVES: The aim of this study was to assess variation of qualitative and quantitative PET/CT image quality parameters with acquisition time, injection activity and body mass for a representative group of adults undergoing whole-body PET/CT imaging. METHODS: PET scan data from sixty patients were reconstructed with a scan time of 1, 2 and 3 min/bed position. These images were visually scored and three quantitative parameters were calculated: noise equivalent counts per axial length (NECpatient), noise equivalent count density (NECdensity) and liver signal to noise ratio (liver SNR). The ability of the three quantitative parameters to discriminate qualitative image quality was assessed using ROC analysis. RESULTS: The quantitative parameters were shown to discriminate images of good/excellent quality from those of poorer image quality with a high degree of accuracy (ROC area >0.9); further, NECpatient had significantly higher discrimination than either NECdensity or liver SNR (ROC area = 0.97). CONCLUSIONS: NECpatient, NECdensity and liver SNR all have high discrimination for qualitatively assessed PET image quality. NECpatient in particular is an effective objective indicator of patient image quality, which will help to assess and standardise scan protocols for purposes such as multi-centre research trials.
Authors: Marcelo A Queiroz; Gaspar Delso; Scott Wollenweber; Timothy Deller; Konstantinos Zeimpekis; Martin Huellner; Felipe de Galiza Barbosa; Gustav von Schulthess; Patrick Veit-Haibach Journal: PLoS One Date: 2015-07-06 Impact factor: 3.240
Authors: Jan H Geismar; Paul Stolzmann; Bert-Ram Sah; Irene A Burger; Burkhardt Seifert; Gaspar Delso; Gustav K von Schulthess; Patrick Veit-Haibach; Lars Husmann Journal: Acta Radiol Open Date: 2015-01-29
Authors: Fred Wickham; Helena McMeekin; Maria Burniston; Daniel McCool; Deborah Pencharz; Annah Skillen; Thomas Wagner Journal: EJNMMI Res Date: 2017-01-13 Impact factor: 3.138
Authors: Christina P W Cox; Daniëlle M E van Assema; Frederik A Verburg; Tessa Brabander; Mark Konijnenberg; Marcel Segbers Journal: EJNMMI Res Date: 2021-07-19 Impact factor: 3.138