| Literature DB >> 23925486 |
Jicong Cao1, Manish Arha, Chaitanya Sudrik, Lukasz J Bugaj, David V Schaffer, Ravi S Kane.
Abstract
A genetically encoded optogenetic system was constructed that activates mRNA translation in mammalian cells in response to light. Blue light induces the reconstitution of an RNA binding domain and a translation initiation domain, thereby activating target mRNA translation downstream of the binding sites.Entities:
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Year: 2013 PMID: 23925486 DOI: 10.1039/c3cc44866e
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222