Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Up-regulation of HOTAIR long non-coding RNA in human gastric adenocarcinoma tissues.

Literature DB >> 23888369

Up-regulation of HOTAIR long non-coding RNA in human gastric adenocarcinoma tissues.

Mohammadreza Hajjari¹, Mehrdad Behmanesh, Majid Sadeghizadeh, Mehdi Zeinoddini.

Abstract

HOTAIR is a known long non-coding RNA which has recently been associated with the progression of some cancer types. It has been reported that HOTAIR expression is correlated with SUZ12 expression level and therefore may affect the epigenetic state of cancer tissues. Here, we found aberrant up-regulation of HOTAIR in gastric adenocarcinoma samples compared with normal adjacent gastric epithelium tissues. Besides, we found that the aberrant expression of HOTAIR was associated with TNM staging and lymph node metastasis of gastric tumors. Here, a potential cooperative expression between HOTAIR and SUZ12 genes in gastric adenocarcinoma tissues is deduced. This result suggests a role for HOTAIR long non-coding RNA in gastric cancer progression.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 2013 PMID： 23888369 DOI： 10.1007/s12032-013-0670-0

Source DB: PubMed Journal: Med Oncol ISSN： 1357-0560 Impact factor: 3.064

12 in total

1. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.

Authors: K J Livak; T D Schmittgen
Journal: Methods Date: 2001-12 Impact factor: 3.608

Review 2. Long non-coding RNAs and cancer: a new frontier of translational research?

Authors: R Spizzo; M I Almeida; A Colombatti; G A Calin
Journal: Oncogene Date: 2012-01-23 Impact factor: 9.867

3. Up-regulated long non-coding RNA H19 contributes to proliferation of gastric cancer cells.

Authors: Feng Yang; Jianwei Bi; Xuchao Xue; Luming Zheng; Kangkang Zhi; Jide Hua; Guoen Fang
Journal: FEBS J Date: 2012-07-31 Impact factor: 5.542

Review 4. RNA meets chromatin.

Authors: Emily Bernstein; C David Allis
Journal: Genes Dev Date: 2005-07-15 Impact factor: 11.361

5. Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers.

Authors: Ryunosuke Kogo; Teppei Shimamura; Koshi Mimori; Kohichi Kawahara; Seiya Imoto; Tomoya Sudo; Fumiaki Tanaka; Kohei Shibata; Akira Suzuki; Shizuo Komune; Satoru Miyano; Masaki Mori
Journal: Cancer Res Date: 2011-08-23 Impact factor: 12.701

6. Junctional adhesion molecules 2 and 3 may potentially be involved in progression of gastric adenocarcinoma tumors.

Authors: Mohammadreza Hajjari; Mehrdad Behmanesh; Majid Sadeghizadeh; Mehdi Zeinoddini
Journal: Med Oncol Date: 2013-01-01 Impact factor: 3.064

7. Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation.

Authors: Zhe Yang; Lin Zhou; Li-Ming Wu; Ming-Chun Lai; Hai-Yang Xie; Feng Zhang; Shu-Sen Zheng
Journal: Ann Surg Oncol Date: 2011-02-15 Impact factor: 5.344

8. Long non-coding RNA HOTAIR is an independent prognostic marker for nasopharyngeal carcinoma progression and survival.

Authors: Yan Nie; Xiang Liu; Shaohua Qu; Erwei Song; Hua Zou; Chang Gong
Journal: Cancer Sci Date: 2013-01-30 Impact factor: 6.716

9. HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer.

Authors: K Kim; I Jutooru; G Chadalapaka; G Johnson; J Frank; R Burghardt; S Kim; S Safe
Journal: Oncogene Date: 2012-05-21 Impact factor: 9.867

10. A central role for long non-coding RNA in cancer.

Authors: Sheetal A Mitra; Anirban P Mitra; Timothy J Triche
Journal: Front Genet Date: 2012-02-15 Impact factor: 4.599

63 in total

1. Competing endogenous RNA: A novel posttranscriptional regulatory dimension associated with the progression of cancer.

Authors: Qingsong Dai; Jixia Li; Keyuan Zhou; Tong Liang
Journal: Oncol Lett Date: 2015-09-14 Impact factor: 2.967

2. lincRNA HOTAIR as a novel promoter of cancer progression.

Authors: Gregory Loewen; Ying Zhuo; Yan Zhuang; Janarthanan Jayawickramarajah; Bin Shan
Journal: J Can Res Updates Date: 2014-07

Review 3. Long non-coding RNAs in gastric cancer: versatile mechanisms and potential for clinical translation.

Authors: Jing Zhao; Yongchao Liu; Guangjian Huang; Peng Cui; Wenhong Zhang; Ying Zhang
Journal: Am J Cancer Res Date: 2015-02-15 Impact factor: 6.166

Review 4. Molecular function and regulation of long non-coding RNAs: paradigms with potential roles in cancer.

Authors: Mohammadreza Hajjari; Atefeh Khoshnevisan; Young Kee Shin
Journal: Tumour Biol Date: 2014-09-30

5. Expression of long noncoding RNA-HOX transcript antisense intergenic RNA in oral squamous cell carcinoma and effect on cell growth.

Authors: Jie Wu; Hongjun Xie
Journal: Tumour Biol Date: 2015-06-03

10. HOTAIR is a predictive and prognostic biomarker for patients with advanced gastric adenocarcinoma receiving fluorouracil and platinum combination chemotherapy.

Authors: Wei Zhao; Shuang Dong; Bensong Duan; Ping Chen; Lei Shi; Hengjun Gao; Haizhi Qi
Journal: Am J Transl Res Date: 2015-07-15 Impact factor: 4.060