Literature DB >> 2387768

A novel antifungal antibiotic, FR-900848. I. Production, isolation, physico-chemical and biological properties.

M Yoshida1, M Ezaki, M Hashimoto, M Yamashita, N Shigematsu, M Okuhara, M Kohsaka, K Horikoshi.   

Abstract

Streptoverticillium fervens produced a new antibiotic, FR-900848, which has a high specific activity against filamentous fungi. Purified by solvent extraction and column chromatography, the compound appears as colorless crystals. Its structure is C32H43N3O6, which consists of 5'-amino-5'-deoxy-5,6-dihydrouridine with an unsaturated fatty acid having unprecedented four serial and one isolated cyclopropane rings.

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Year:  1990        PMID: 2387768     DOI: 10.7164/antibiotics.43.748

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  11 in total

1.  Selective catalytic hydrogenation of the N-acyl and uridyl double bonds in the tunicamycin family of protein N-glycosylation inhibitors.

Authors:  Neil Pj Price; Michael A Jackson; Karl E Vermillion; Judith A Blackburn; Jiakun Li; Biao Yu
Journal:  J Antibiot (Tokyo)       Date:  2017-11-01       Impact factor: 2.649

Review 2.  Enzymatic chemistry of cyclopropane, epoxide, and aziridine biosynthesis.

Authors:  Christopher J Thibodeaux; Wei-chen Chang; Hung-wen Liu
Journal:  Chem Rev       Date:  2011-10-21       Impact factor: 60.622

Review 3.  Oxidative Cyclization in Natural Product Biosynthesis.

Authors:  Man-Cheng Tang; Yi Zou; Kenji Watanabe; Christopher T Walsh; Yi Tang
Journal:  Chem Rev       Date:  2016-12-12       Impact factor: 60.622

Review 4.  Compounds active against cell walls of medically important fungi.

Authors:  R F Hector
Journal:  Clin Microbiol Rev       Date:  1993-01       Impact factor: 26.132

Review 5.  Making and breaking carbon-carbon bonds in class C radical SAM methyltransferases.

Authors:  Marley A Brimberry; Liju Mathew; William Lanzilotta
Journal:  J Inorg Biochem       Date:  2021-10-22       Impact factor: 4.155

6.  Electrochemical borylation of carboxylic acids.

Authors:  Lisa M Barton; Longrui Chen; Donna G Blackmond; Phil S Baran
Journal:  Proc Natl Acad Sci U S A       Date:  2021-08-24       Impact factor: 11.205

Review 7.  Novel Promising Antifungal Target Proteins for Conquering Invasive Fungal Infections.

Authors:  Cheng Zhen; Hui Lu; Yuanying Jiang
Journal:  Front Microbiol       Date:  2022-06-16       Impact factor: 6.064

8.  One-pot catalytic enantio- and diastereoselective syntheses of anti-, syn-cis-disubstituted, and syn-vinyl cyclopropyl alcohols.

Authors:  Hun Young Kim; Luca Salvi; Patrick J Carroll; Patrick J Walsh
Journal:  J Am Chem Soc       Date:  2010-01-13       Impact factor: 15.419

Review 9.  Natural and engineered biosynthesis of nucleoside antibiotics in Actinomycetes.

Authors:  Wenqing Chen; Jianzhao Qi; Pan Wu; Dan Wan; Jin Liu; Xuan Feng; Zixin Deng
Journal:  J Ind Microbiol Biotechnol       Date:  2015-07-08       Impact factor: 3.346

10.  Farnesides A and B, sesquiterpenoid nucleoside ethers from a marine-derived Streptomyces sp., strain CNT-372 from Fiji.

Authors:  Ella Zafrir Ilan; Manuel R Torres; Jacques Prudhomme; Karine Le Roch; Paul R Jensen; William Fenical
Journal:  J Nat Prod       Date:  2013-08-29       Impact factor: 4.050

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