Literature DB >> 2366633

Delta 6 desaturase in brain and liver during development and aging.

J M Bourre1, M Piciotti, O Dumont.   

Abstract

delta 6 Desaturase was measured in the mouse brain and liver using linoleic acid as substrate. During pre- and postnatal development, delta 6 desaturase in brain decreased dramatically (12-fold) up to postnatal day 21 and remained nearly constant thereafter. In liver, the activity increased approximately 9-fold between day 3 before birth and day 7 after birth. Then it decreased slightly up to weaning and was approximately constant up to 4 mo. From then on, delta 6 desaturase decreased with age (40% between 4 and 17 mo).

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Year:  1990        PMID： 2366633     DOI： 10.1007/bf02544347

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  29 in total

1.  Palmityl-CoA and stearyl-CoA desaturase in mouse brain microsomes during development in normal and neurological mutants (Quaking and Jimpy).

Authors:  J P Carreau; O Daudu; P Mazliak; J M Bourre
Journal:  J Neurochem       Date:  1979-02       Impact factor: 5.372

2.  Effect of maternal essential fatty acid supply on fatty acid composition of brain, liver, muscle and serum in 21-day-old rats.

Authors:  C Alling; A Bruce; I Karlsson; O Sapia; L Svennerholm
Journal:  J Nutr       Date:  1972-06       Impact factor: 4.798

3.  [Desaturation of linoleic acid by liver and brain microsomes of growing rats].

Authors:  C Strouvé-Vallet; M Pascaud
Journal:  Biochimie       Date:  1971       Impact factor: 4.079

4.  delta 6-, delta 5-fatty acyl-CoA desaturases and gamma-linolenyl-CoA elongase in regenerating rat liver.

Authors:  J P Carreau; P Mazliak; D Frommel
Journal:  Int J Biochem       Date:  1981

5.  Chain elongation-desaturation of linoleic acid during the development of the pig. Implications for the supply of polyenoic fatty acids to the developing brain.

Authors:  J M Purvis; M T Clandinin; R R Hacker
Journal:  Comp Biochem Physiol B       Date:  1983

6.  Nervonic acid biosynthesis by erucyl-CoA elongation in normal and quaking mouse brain microsomes. Elongation of other unsaturated fatty acyl-CoAs (mono and poly-unsaturated).

Authors:  J M Bourre; O Daudu; N Baumann
Journal:  Biochim Biophys Acta       Date:  1976-01-22

7.  Effect of polyunsaturated fatty acids on fetal mouse brain cells in culture in a chemically defined medium.

Authors:  J M Bourre; A Faivre; O Dumont; A Nouvelot; C Loudes; J Puymirat; A Tixier-Vidal
Journal:  J Neurochem       Date:  1983-11       Impact factor: 5.372

8.  [Comparative desaturation of linoleic and dihomo-gamma-linolenic acids by homogenates of human liver in vitro].

Authors:  J P Blond; P Lemarchal; D Spielmann
Journal:  C R Seances Acad Sci III       Date:  1981-05-04

9.  [In vitro study of delta-6- and delta-5-desaturation of linoleic and dihomo-gamma-linolenic acids in WKY rats on a high-sodium diet].

Authors:  M Narce; J P Poisson
Journal:  C R Seances Soc Biol Fil       Date:  1985

10.  Alteration in fatty acid composition of adult rat brain capillaries and choroid plexus induced by a diet deficient in n-3 fatty acids: slow recovery after substitution with a nondeficient diet.

Authors:  P Homayoun; G Durand; G Pascal; J M Bourre
Journal:  J Neurochem       Date:  1988-07       Impact factor: 5.372
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  20 in total

1.  Enhancing plant seed oils for human nutrition.

Authors:  Howard G Damude; Anthony J Kinney
Journal:  Plant Physiol       Date:  2008-07       Impact factor: 8.340

2.  Aging decreases rate of docosahexaenoic acid synthesis-secretion from circulating unesterified α-linolenic acid by rat liver.

Authors:  Fei Gao; Ameer Y Taha; Kaizong Ma; Lisa Chang; Dale Kiesewetter; Stanley I Rapoport
Journal:  Age (Dordr)       Date:  2012-03-03

3.  High dietary 18:3n-3 increases the 18:3n-3 but not the 22:6n-3 content in the whole body, brain, skin, epididymal fat pads, and muscles of suckling rat pups.

Authors:  R A Bowen; M T Clandinin
Journal:  Lipids       Date:  2000-04       Impact factor: 1.880

4.  Executive functions and the ω-6-to-ω-3 fatty acid ratio: a cross-sectional study.

Authors:  Kelly W Sheppard; Carol L Cheatham
Journal:  Am J Clin Nutr       Date:  2016-11-16       Impact factor: 7.045

5.  Fads3 modulates docosahexaenoic acid in liver and brain.

Authors:  Ji Yao Zhang; Xia Qin; Allison Liang; Ellen Kim; Peter Lawrence; Woo Jung Park; Kumar S D Kothapalli; J Thomas Brenna
Journal:  Prostaglandins Leukot Essent Fatty Acids       Date:  2017-07-08       Impact factor: 4.006

6.  Dietary n-6 PUFA deprivation for 15 weeks reduces arachidonic acid concentrations while increasing n-3 PUFA concentrations in organs of post-weaning male rats.

Authors:  Miki Igarashi; Fei Gao; Hyung-Wook Kim; Kaizong Ma; Jane M Bell; Stanley I Rapoport
Journal:  Biochim Biophys Acta       Date:  2008-11-27

7.  Age-related changes in delta 6 and delta 5 desaturase activities in rat liver microsomes.

Authors:  C Maniongui; J P Blond; L Ulmann; G Durand; J P Poisson; J Bézard
Journal:  Lipids       Date:  1993-04       Impact factor: 1.880

8.  Effect of age and alpha-linolenic acid deficiency on delta 6 desaturase activity and liver lipids in rats.

Authors:  T K Dinh; J M Bourre; G Durand
Journal:  Lipids       Date:  1993-06       Impact factor: 1.880

9.  Dietary fish oil replacement with lard and soybean oil affects triacylglycerol and phospholipid muscle and liver docosahexaenoic acid content but not in the brain and eyes of surubim juveniles Pseudoplatystoma sp.

Authors:  M D Noffs; R C Martino; L C Trugo; E C Urbinati; J B K Fernandes; L S Takahashi
Journal:  Fish Physiol Biochem       Date:  2008-11-07       Impact factor: 2.794

10.  Increments of dietary linoleate raise liver arachidonate, but markedly reduce heart n-6 and n-3 fatty acids in the rat.

Authors:  F Marangoni; C Mosconi; G Galella; C Galli
Journal:  Lipids       Date:  1992-08       Impact factor: 1.880
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