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Literature DB >> 23642191

Asperterpenols A and B, new sesterterpenoids isolated from a mangrove endophytic fungus Aspergillus sp. 085242.

Ze'en Xiao¹, Huarong Huang, Changlun Shao, Xuekui Xia, Lin Ma, Xishan Huang, Yongjun Lu, Yongcheng Lin, Yuhua Long, Zhigang She.

Abstract

Asperterpenol A (1) and asperterpenol B (2), two novel sesterterpenoids with an unusual 5/8/6/6 tetracyclic ring skeleton, were isolated from a mangrove endophytic fungus Aspergillus sp. 085242. The structures were elucidated on the basis of spectroscopic methods and the absolute configurations determined by single-crystal X-ray diffraction analysis. Compounds 1 and 2 inhibit acetylcholinesterase with IC50 values of 2.3 and 3.0 μM, respectively.

Entities: Chemical Species

Mesh：

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Year: 2013 PMID： 23642191 DOI： 10.1021/ol401005j

Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005

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Cited

19 in total

1. Cytochalasins from cultures of endophytic fungus Phoma multirostrata EA-12.

Authors: Zi-ming Chen; He-Ping Chen; Yan Li; Tao Feng; Ji-Kai Liu
Journal: J Antibiot (Tokyo) Date: 2014-06-25 Impact factor: 2.649

2. Bioactive Metabolites from Mangrove Endophytic Fungus Aspergillus sp. 16-5B.

Authors: Yayue Liu; Senhua Chen; Zhaoming Liu; Yongjun Lu; Guoping Xia; Hongju Liu; Lei He; Zhigang She
Journal: Mar Drugs Date: 2015-05-19 Impact factor: 5.118

Review 3. Bioactive terpenes from marine-derived fungi.

Authors: Ahmed M Elissawy; Mohamed El-Shazly; Sherif S Ebada; AbdelNasser B Singab; Peter Proksch
Journal: Mar Drugs Date: 2015-04-03 Impact factor: 5.118

4. New depsidones and isoindolinones from the mangrove endophytic fungus Meyerozyma guilliermondii (HZ-Y2) isolated from the South China Sea.

Authors: Senhua Chen; Zhaoming Liu; Yayue Liu; Yongjun Lu; Lei He; Zhigang She
Journal: Beilstein J Org Chem Date: 2015-07-16 Impact factor: 2.883

5. New dimeric members of the phomoxanthone family: phomolactonexanthones A, B and deacetylphomoxanthone C isolated from the fungus Phomopsis sp.

Authors: Bo Ding; Jie Yuan; Xishan Huang; Weitao Wen; Xu Zhu; Yayue Liu; Hanxiang Li; Yongjun Lu; Lei He; Hongmei Tan; Zhigang She
Journal: Mar Drugs Date: 2013-12-11 Impact factor: 5.118

10. Polyketides from the Mangrove-Derived Endophytic Fungus Nectria sp. HN001 and Their α-Glucosidase Inhibitory Activity.

Authors: Hui Cui; Yayue Liu; Yang Nie; Zhaoming Liu; Senhua Chen; Zhengrui Zhang; Yongjun Lu; Lei He; Xishan Huang; Zhigang She
Journal: Mar Drugs Date: 2016-04-28 Impact factor: 5.118

Asperterpenols A and B, new sesterterpenoids isolated from a mangrove endophytic fungus Aspergillus sp. 085242.

1. Cytochalasins from cultures of endophytic fungus Phoma multirostrata EA-12.

2. Bioactive Metabolites from Mangrove Endophytic Fungus Aspergillus sp. 16-5B.

Review 3. Bioactive terpenes from marine-derived fungi.

4. New depsidones and isoindolinones from the mangrove endophytic fungus Meyerozyma guilliermondii (HZ-Y2) isolated from the South China Sea.

5. New dimeric members of the phomoxanthone family: phomolactonexanthones A, B and deacetylphomoxanthone C isolated from the fungus Phomopsis sp.

6. Eurothiocin A and B, sulfur-containing benzofurans from a soft coral-derived fungus Eurotium rubrum SH-823.

7. Asperlones A and B, dinaphthalenone derivatives from a mangrove endophytic fungus Aspergillus sp. 16-5C.

8. Bioactive isopimarane diterpenes from the fungus, Epicoccum sp. HS-1, associated with Apostichopus japonicus.

9. Sorokiniol: a new enzymes inhibitory metabolite from fungal endophyte Bipolaris sorokiniana LK12.

10. Polyketides from the Mangrove-Derived Endophytic Fungus Nectria sp. HN001 and Their α-Glucosidase Inhibitory Activity.