Literature DB >> 24961709

Cytochalasins from cultures of endophytic fungus Phoma multirostrata EA-12.

Zi-ming Chen1, He-Ping Chen2, Yan Li1, Tao Feng1, Ji-Kai Liu1.   

Abstract

Two new cytochalsians, multirostratin A (1) and 20-oxo-deoxaphomin (2), together with five known analogues (3-7), were obtained from the endophytic fungus Phoma multirostrata EA-12. The structures of 1 and 2 were elucidated by MS and 1D- and 2D-NMR spectroscopic data analyses, as well as by comparison of data with those of analogues reported in the literature. Compounds 1 and 2 showed moderate cytotoxicity against five tumor cell lines (HL-60, A-549, SMMC-7721, MCF-7 and SW-480).

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 24961709     DOI： 10.1038/ja.2014.87

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  12 in total

Review 1.  Endophytes: a rich source of functional metabolites.

Authors:  R X Tan; W X Zou
Journal:  Nat Prod Rep       Date:  2001-08       Impact factor: 13.423

2.  Pimarane diterpene and cytochalasin derivatives from the endophytic fungus Eutypella scoparia PSU-D44.

Authors:  Wipapan Pongcharoen; Vatcharin Rukachaisirikul; Souwalak Phongpaichit; Nattawut Rungjindamai; Jariya Sakayaroj
Journal:  J Nat Prod       Date:  2006-05       Impact factor: 4.050

Review 3.  Anticancer compounds derived from fungal endophytes: their importance and future challenges.

Authors:  Ravindra N Kharwar; Ashish Mishra; Surendra K Gond; Andrea Stierle; Donald Stierle
Journal:  Nat Prod Rep       Date:  2011-04-01       Impact factor: 13.423

4.  Cytochalasins Z1, Z2 and Z3, three 24-oxa[14]cytochalasans produced by Pyrenophora semeniperda.

Authors:  Antonio Evidente; Anna Andolfi; Maurizio Vurro; Maria Chiara Zonno; Andrea Motta
Journal:  Phytochemistry       Date:  2002-05       Impact factor: 4.072

5.  L-696,474, a novel cytochalasin as an inhibitor of HIV-1 protease. III. Biological activity.

Authors:  R B Lingham; A Hsu; K C Silverman; G F Bills; A Dombrowski; M E Goldman; P L Darke; L Huang; G Koch; J G Ondeyka
Journal:  J Antibiot (Tokyo)       Date:  1992-05       Impact factor: 2.649

6.  Lobophorins E and F, new spirotetronate antibiotics from a South China Sea-derived Streptomyces sp. SCSIO 01127.

Authors:  Siwen Niu; Sumei Li; Yuchan Chen; Xinpeng Tian; Haibo Zhang; Guangtao Zhang; Weimin Zhang; Xiaohong Yang; Si Zhang; Jianhua Ju; Changsheng Zhang
Journal:  J Antibiot (Tokyo)       Date:  2011-09-07       Impact factor: 2.649

7.  Periconiasins A-C, new cytotoxic cytochalasans with an unprecedented 9/6/5 tricyclic ring system from endophytic fungus Periconia sp.

Authors:  Dewu Zhang; Hanlin Ge; Dan Xie; Ridao Chen; Jian-hua Zou; Xiaoyu Tao; Jungui Dai
Journal:  Org Lett       Date:  2013-03-18       Impact factor: 6.005

8.  Asperterpenols A and B, new sesterterpenoids isolated from a mangrove endophytic fungus Aspergillus sp. 085242.

Authors:  Ze'en Xiao; Huarong Huang; Changlun Shao; Xuekui Xia; Lin Ma; Xishan Huang; Yongjun Lu; Yongcheng Lin; Yuhua Long; Zhigang She
Journal:  Org Lett       Date:  2013-05-03       Impact factor: 6.005

9.  Cytochalasins Z4, Z5, and Z6, three new 24-Oxa[14]cytochalasans produced by Phoma exigua var. heteromorpha.

Authors:  Antonio Evidente; Anna Andolfi; Maurizio Vurro; Maria Chiara Zonno; Andrea Motta
Journal:  J Nat Prod       Date:  2003-12       Impact factor: 4.050

10.  Geniculol, a new biologically active diterpene from the endophytic fungus geniculosporium sp.1

Authors: 
Journal:  J Nat Prod       Date:  1999-01       Impact factor: 4.050
View more
  2 in total

Review 1.  Fungal Endophytes: an Accessible Source of Bioactive Compounds with Potential Anticancer Activity.

Authors:  Nilesh Rai; Priyamvada Gupta; Priyanka Kumari Keshri; Ashish Verma; Pradeep Mishra; Deepak Kumar; Ajay Kumar; Santosh Kumar Singh; Vibhav Gautam
Journal:  Appl Biochem Biotechnol       Date:  2022-03-29       Impact factor: 2.926

2.  Antiproliferative and Cytotoxic Cytochalasins from Sparticola triseptata Inhibit Actin Polymerization and Aggregation.

Authors:  Katherine Yasmin M Garcia; Mark Tristan J Quimque; Christopher Lambert; Katharina Schmidt; Gian Primahana; Theresia E B Stradal; Andreas Ratzenböck; Hans-Martin Dahse; Chayanard Phukhamsakda; Marc Stadler; Frank Surup; Allan Patrick G Macabeo
Journal:  J Fungi (Basel)       Date:  2022-05-25
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.