PURPOSE: In diffusion MRI, a technique known as diffusion spectrum imaging reconstructs the propagator with a discrete Fourier transform, from a Cartesian sampling of the diffusion signal. Alternatively, it is possible to directly reconstruct the orientation distribution function in q-ball imaging, providing so-called high angular resolution diffusion imaging. In between these two techniques, acquisitions on several spheres in q-space offer an interesting trade-off between the angular resolution and the radial information gathered in diffusion MRI. A careful design is central in the success of multishell acquisition and reconstruction techniques. METHODS: The design of acquisition in multishell is still an open and active field of research, however. In this work, we provide a general method to design multishell acquisition with uniform angular coverage. This method is based on a generalization of electrostatic repulsion to multishell. RESULTS: We evaluate the impact of our method using simulations, on the angular resolution in one and two bundles of fiber configurations. Compared to more commonly used radial sampling, we show that our method improves the angular resolution, as well as fiber crossing discrimination. DISCUSSION: We propose a novel method to design sampling schemes with optimal angular coverage and show the positive impact on angular resolution in diffusion MRI.
PURPOSE: In diffusion MRI, a technique known as diffusion spectrum imaging reconstructs the propagator with a discrete Fourier transform, from a Cartesian sampling of the diffusion signal. Alternatively, it is possible to directly reconstruct the orientation distribution function in q-ball imaging, providing so-called high angular resolution diffusion imaging. In between these two techniques, acquisitions on several spheres in q-space offer an interesting trade-off between the angular resolution and the radial information gathered in diffusion MRI. A careful design is central in the success of multishell acquisition and reconstruction techniques. METHODS: The design of acquisition in multishell is still an open and active field of research, however. In this work, we provide a general method to design multishell acquisition with uniform angular coverage. This method is based on a generalization of electrostatic repulsion to multishell. RESULTS: We evaluate the impact of our method using simulations, on the angular resolution in one and two bundles of fiber configurations. Compared to more commonly used radial sampling, we show that our method improves the angular resolution, as well as fiber crossing discrimination. DISCUSSION: We propose a novel method to design sampling schemes with optimal angular coverage and show the positive impact on angular resolution in diffusion MRI.
Authors: Liang Zhan; Alex D Leow; Neda Jahanshad; Ming-Chang Chiang; Marina Barysheva; Agatha D Lee; Arthur W Toga; Katie L McMahon; Greig I de Zubicaray; Margaret J Wright; Paul M Thompson Journal: Neuroimage Date: 2009-10-09 Impact factor: 6.556
Authors: Kurt G Schilling; Yurui Gao; Iwona Stepniewska; Vaibhav Janve; Bennett A Landman; Adam W Anderson Journal: NMR Biomed Date: 2019-03-25 Impact factor: 4.044
Authors: Ralf Lützkendorf; Robin M Heidemann; Thorsten Feiweier; Michael Luchtmann; Sebastian Baecke; Jörn Kaufmann; Jörg Stadler; Eike Budinger; Johannes Bernarding Journal: MAGMA Date: 2018-09-17 Impact factor: 2.310
Authors: Kurt Schilling; Yurui Gao; Vaibhav Janve; Iwona Stepniewska; Bennett A Landman; Adam W Anderson Journal: NMR Biomed Date: 2017-09-15 Impact factor: 4.044
Authors: Farshid Sepehrband; Ryan P Cabeen; Jeiran Choupan; Giuseppe Barisano; Meng Law; Arthur W Toga Journal: Neuroimage Date: 2019-04-30 Impact factor: 6.556
Authors: Gaëtan Rensonnet; Benoît Scherrer; Gabriel Girard; Aleksandar Jankovski; Simon K Warfield; Benoît Macq; Jean-Philippe Thiran; Maxime Taquet Journal: Neuroimage Date: 2018-09-30 Impact factor: 6.556