Literature DB >> 23618720

Vertebrate animal models of glioma: understanding the mechanisms and developing new therapies.

Leon Chen1, Yuqing Zhang, Jingxuan Yang, John P Hagan, Min Li.   

Abstract

Glioblastoma Multiforme (GBM) is recognized as one of the most deadly cancers characterized by cellular atypia, severe necrosis, and high rate of angiogenesis. In this review, we discuss a diversified group of GBM xenograft models and compare them with the genetically engineered mouse (GEM) model systems. Next, we describe common genetic defects observed in GBM and numerous GEM models that recapitulate these abnormalities. Finally, we focus on the clinical value of other vertebrate animal models such as the canine model by examining their contributions to GBM research.
Copyright © 2013 Elsevier B.V. All rights reserved.

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Year:  2013        PMID： 23618720      PMCID： PMC3729034          DOI： 10.1016/j.bbcan.2013.04.003

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  81 in total

Review 1.  Malignant glioma: genetics and biology of a grave matter.

Authors:  E A Maher; F B Furnari; R M Bachoo; D H Rowitch; D N Louis; W K Cavenee; R A DePinho
Journal:  Genes Dev       Date:  2001-06-01       Impact factor: 11.361

2.  Astrocyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation.

Authors:  Andrew Xiao; Hua Wu; Pier Paolo Pandolfi; David N Louis; Terry Van Dyke
Journal:  Cancer Cell       Date:  2002-03       Impact factor: 31.743

3.  Further investigations on the origin of tumors in mice. III. On the part played by internal secretion in the spontaneous development of tumors.

Authors:  A E Lathrop; L Loeb
Journal:  J Cancer Res       Date:  1916-01

Review 4.  The INK4A/ARF locus: role in cell cycle control and apoptosis and implications for glioma growth.

Authors:  S M Ivanchuk; S Mondal; P B Dirks; J T Rutka
Journal:  J Neurooncol       Date:  2001-02       Impact factor: 4.130

Review 5.  Glioma models.

Authors:  C Dai; E C Holland
Journal:  Biochim Biophys Acta       Date:  2001-08-31

6.  Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN.

Authors:  D Koul; R Parthasarathy; R Shen; M A Davies; S A Jasser; S K Chintala; J S Rao; Y Sun; E N Benvenisite; T J Liu; W K Yung
Journal:  Oncogene       Date:  2001-10-11       Impact factor: 9.867

7.  Preclinical evaluation of a novel device for delivering brachytherapy to the margins of resected brain tumor cavities.

Authors:  James B Stubbs; Roger H Frankel; Karl Schultz; Ian Crocker; Dirck Dillehay; Jeffrey J Olson
Journal:  J Neurosurg       Date:  2002-02       Impact factor: 5.115

8.  Canine neoplasia in the UK: estimates of incidence rates from a population of insured dogs.

Authors:  J M Dobson; S Samuel; H Milstein; K Rogers; J L N Wood
Journal:  J Small Anim Pract       Date:  2002-06       Impact factor: 1.522

9.  Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt.

Authors:  Lene Uhrbom; Chengkai Dai; Joseph C Celestino; Marc K Rosenblum; Gregory N Fuller; Eric C Holland
Journal:  Cancer Res       Date:  2002-10-01       Impact factor: 12.701

Review 10.  The molecular and genetic basis of neurological tumours.

Authors:  Yuan Zhu; Luis F Parada
Journal:  Nat Rev Cancer       Date:  2002-08       Impact factor: 60.716
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  35 in total

1.  Comparison of Allogeneic and Syngeneic Rat Glioma Models by Using MRI and Histopathologic Evaluation.

Authors:  Elena Biasibetti; Alberto Valazza; Maria T Capucchio; Laura Annovazzi; Luigi Battaglia; Daniela Chirio; Marina Gallarate; Marta Mellai; Elisabetta Muntoni; Elena Peira; Chiara Riganti; Davide Schiffer; Pierpaolo Panciani; Michele Lanotte
Journal:  Comp Med       Date:  2017-03-01       Impact factor: 0.982

2.  Targeting Hypoxia-Inducible Factor 1α in a New Orthotopic Model of Glioblastoma Recapitulating the Hypoxic Tumor Microenvironment.

Authors:  Fares Nigim; Jill Cavanaugh; Anoop P Patel; William T Curry; Shin-ichi Esaki; Ekkehard M Kasper; Andrew S Chi; David N Louis; Robert L Martuza; Samuel D Rabkin; Hiroaki Wakimoto
Journal:  J Neuropathol Exp Neurol       Date:  2015-07       Impact factor: 3.685

3.  miR-181 subunits enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeleton remodeling in glioblastoma cells.

Authors:  Xiaoling She; Zhibin Yu; Yulong Cui; Qianqian Lei; Zeyou Wang; Gang Xu; Zhaohui Luo; Guiyuan Li; Minghua Wu
Journal:  Med Oncol       Date:  2014-02-27       Impact factor: 3.064

Review 4.  Dogs are man's best friend: in sickness and in health.

Authors:  R Timothy Bentley; Atique U Ahmed; Amy B Yanke; Aaron A Cohen-Gadol; Mahua Dey
Journal:  Neuro Oncol       Date:  2017-03-01       Impact factor: 12.300

Review 5.  Targeted delivery of antibody-based therapeutic and imaging agents to CNS tumors: crossing the blood-brain barrier divide.

Authors:  Ann-Marie Chacko; Chunsheng Li; Daniel A Pryma; Steven Brem; George Coukos; Vladimir Muzykantov
Journal:  Expert Opin Drug Deliv       Date:  2013-06-11       Impact factor: 6.648

Review 6.  Therapeutic Hypothesis Testing With Rodent Brain Tumor Models.

Authors:  Derek A Wainwright; Craig M Horbinski; Rintaro Hashizume; C David James
Journal:  Neurotherapeutics       Date:  2017-04       Impact factor: 7.620

Review 7.  Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge.

Authors:  Dominik Sturm; Sebastian Bender; David T W Jones; Peter Lichter; Jacques Grill; Oren Becher; Cynthia Hawkins; Jacek Majewski; Chris Jones; Joseph F Costello; Antonio Iavarone; Kenneth Aldape; Cameron W Brennan; Nada Jabado; Stefan M Pfister
Journal:  Nat Rev Cancer       Date:  2014-02       Impact factor: 60.716

Review 8.  Leveraging the replication-competent avian-like sarcoma virus/tumor virus receptor-A system for modeling human gliomas.

Authors:  Pranjali P Kanvinde; Adarsha P Malla; Nina P Connolly; Frank Szulzewsky; Pavlos Anastasiadis; Heather M Ames; Anthony J Kim; Jeffrey A Winkles; Eric C Holland; Graeme F Woodworth
Journal:  Glia       Date:  2021-02-27       Impact factor: 7.452

Review 9.  Modeling human brain tumors in flies, worms, and zebrafish: From proof of principle to novel therapeutic targets.

Authors:  Uswa Shahzad; Michael S Taccone; Sachin A Kumar; Hidehiro Okura; Stacey Krumholtz; Joji Ishida; Coco Mine; Kyle Gouveia; Julia Edgar; Christian Smith; Madeline Hayes; Xi Huang; W Brent Derry; Michael D Taylor; James T Rutka
Journal:  Neuro Oncol       Date:  2021-05-05       Impact factor: 12.300

10.  Clinical features, diagnosis, and survival analysis of dogs with glioma.

Authors:  Roberto José-López; Rodrigo Gutierrez-Quintana; Cristian de la Fuente; Edgar G Manzanilla; Anna Suñol; Dolors Pi Castro; Sonia Añor; Daniel Sánchez-Masian; Francisco Fernández-Flores; Emanuele Ricci; Katia Marioni-Henry; Joan Mascort; Lara A Matiasek; Kaspar Matiasek; Paul M Brennan; Martí Pumarola
Journal:  J Vet Intern Med       Date:  2021-06-12       Impact factor: 3.175
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