| Literature DB >> 17936322 |
R Karthikeyan1, S Karthigayan, M Sri Balasubashini, S T Somasundaram, T Balasubramanian.
Abstract
The antitumor activity of the sea snake venom (Lapemis curtus) was evaluated against Ehrlich's ascites carcinoma (EAC) in Swiss albino mice and HeLa and Hep2 tumor cell cultures. Among the different doses tested, 6.50 microg/ml at 24 h was found to effectively inhibit cancer cell proliferation. The same dose on EAC-bearing mice by i.p. injection significantly reduced the tumor growth and was demonstrated by increased life span of the mice by 201.25%.Entities:
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Year: 2007 PMID： 17936322 DOI： 10.1016/j.toxicon.2007.08.012
Source DB: PubMed Journal: Toxicon ISSN： 0041-0101 Impact factor: 3.033