| Literature DB >> 23582320 |
Hao Wu1.
Abstract
Recent studies have revealed that multiple intracellular signaling proteins may assemble into structured, yet sometimes infinite, higher-order signaling machines for transmission of receptor activation information to cellular responses. These studies advance our understanding of cell signaling and implicate new molecular mechanisms in proximity-driven enzyme activation, threshold behavior, signal amplification, reduction of biological noise, and temporal and spatial control of signal transduction.Entities:
Mesh:
Substances:
Year: 2013 PMID: 23582320 PMCID: PMC3687143 DOI: 10.1016/j.cell.2013.03.013
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582