Literature DB >> 23569701

Diagnosis and treatment of osteoporosis in high-risk patients prior to hip fracture.

Lauren J Gleason1, Isaura B Menzies, Daniel A Mendelson, Stephen L Kates, Susan M Friedman.   

Abstract

PURPOSE: Hip fractures in older adults are common and serious events. Patients who sustain fragility hip fractures are defined as having osteoporosis. Patients with dementia or a history of a prior fragility fracture are at increased risk of a future fracture. This study assesses prefracture osteoporosis diagnosis and treatment in high-risk groups.
METHODS: A case-control analysis of a database of all patients age ≥60 years admitted for surgical repair of nonpathological, low-impact femur fracture between May 2005 and October 2010 was performed.
RESULTS: Of 1070 patients, 511 (47.8%) had dementia and 435 (40.7%) had been diagnosed with osteoporosis prior to admission. Patients with dementia were more likely to have a diagnosis of osteoporosis prior to their fracture than those without dementia (43.8% vs 37.7%, P < .05). Twenty-five percent of the total study population had been treated with calcium and vitamin D (Cal+D) prior to admission, and 12% with other osteoporosis medications. There was a trend toward patients with dementia being more likely to have been on Cal+D prior to admission (27.6% vs 22.5%, P = .06), but no difference in treatment with other agents (10.8% vs 13.1%, P = .25). Patients with prior fragility fractures were more likely to be on Cal+D (32.3% vs 25.0%, P < .02); however, there was no difference in the use of other osteoporosis medications (12.3% vs 12%, P = .90).
CONCLUSION: Fewer than half of patients that presented with hip fractures were diagnosed with osteoporosis prior to fracture and primary preventative treatment rates were low. Although patients with dementia are more likely to be diagnosed with osteoporosis, they were not more likely to be treated, despite having a greater risk. Additionally, those with prior fragility fractures are often not on preventative treatment. This may represent a missed opportunity for prevention and room for improvement in order to reduce osteoporotic hip fractures.

Entities:  

Keywords:  dementia; fragility fractures; geriatric medicine; hip fracture; metabolic bone disorders; osteoporosis

Year:  2012        PMID: 23569701      PMCID: PMC3598403          DOI: 10.1177/2151458512454878

Source DB:  PubMed          Journal:  Geriatr Orthop Surg Rehabil        ISSN: 2151-4585


  29 in total

1.  Cost-effectiveness of oral bisphosphonates for osteoporosis at different ages and levels of life expectancy.

Authors:  Annalise N Pham; Santanu K Datta; Thomas J Weber; Louise C Walter; Cathleen S Colón-Emeric
Journal:  J Am Geriatr Soc       Date:  2011-08-30       Impact factor: 5.562

2.  Recovery from hip fracture in eight areas of function.

Authors:  J Magaziner; W Hawkes; J R Hebel; S I Zimmerman; K M Fox; M Dolan; G Felsenthal; J Kenzora
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2000-09       Impact factor: 6.053

3.  Hip fracture in women without osteoporosis.

Authors:  Stacey A Wainwright; Lynn M Marshall; Kristine E Ensrud; Jane A Cauley; Dennis M Black; Teresa A Hillier; Marc C Hochberg; Molly T Vogt; Eric S Orwoll
Journal:  J Clin Endocrinol Metab       Date:  2005-02-22       Impact factor: 5.958

4.  Adherence of academic geriatric practitioners to osteoporosis screening guidelines.

Authors:  D N McNally; A M Kenny; J-A Smith
Journal:  Osteoporos Int       Date:  2006-10-17       Impact factor: 4.507

5.  A new method of classifying prognostic comorbidity in longitudinal studies: development and validation.

Authors:  M E Charlson; P Pompei; K L Ales; C R MacKenzie
Journal:  J Chronic Dis       Date:  1987

6.  Missed opportunities for osteoporosis treatment in patients hospitalized for hip fracture.

Authors:  Lee A Jennings; Andrew D Auerbach; Judith Maselli; Penelope S Pekow; Peter K Lindenauer; Sei J Lee
Journal:  J Am Geriatr Soc       Date:  2010-04       Impact factor: 5.562

7.  Treating nondementia illnesses in patients with dementia.

Authors:  D J Brauner; J C Muir; G A Sachs
Journal:  JAMA       Date:  2000-06-28       Impact factor: 56.272

8.  Recurrent and injurious falls in the year following hip fracture: a prospective study of incidence and risk factors from the Sarcopenia and Hip Fracture study.

Authors:  Bradley D Lloyd; Dominique A Williamson; Nalin A Singh; Ross D Hansen; Terrence H Diamond; Terence P Finnegan; Barry J Allen; Jodie N Grady; Theodora M Stavrinos; Emma U R Smith; Ashish D Diwan; Maria A Fiatarone Singh
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2009-03-05       Impact factor: 6.053

9.  Bone mineral density thresholds for pharmacological intervention to prevent fractures.

Authors:  Ethel S Siris; Ya-Ting Chen; Thomas A Abbott; Elizabeth Barrett-Connor; Paul D Miller; Lois E Wehren; Marc L Berger
Journal:  Arch Intern Med       Date:  2004-05-24

10.  Dementia and hip fractures: development of a pathogenic framework for understanding and studying risk.

Authors:  Susan M Friedman; Isaura B Menzies; Susan V Bukata; Daniel A Mendelson; Stephen L Kates
Journal:  Geriatr Orthop Surg Rehabil       Date:  2010-11
View more
  10 in total

Review 1.  Fragility fracture programs: are they effective and what is the surgeon's role?

Authors:  Jay S Bender; Eric G Meinberg
Journal:  Curr Osteoporos Rep       Date:  2015-02       Impact factor: 5.096

2.  Evaluation of a Multimodal, Direct-to-Patient Educational Intervention Targeting Barriers to Osteoporosis Care: A Randomized Clinical Trial.

Authors:  Maria I Danila; Ryan C Outman; Elizabeth J Rahn; Amy S Mudano; David T Redden; Peng Li; Jeroan J Allison; Fred A Anderson; Allison Wyman; Susan L Greenspan; Andrea Z LaCroix; Jeri W Nieves; Stuart L Silverman; Ethel S Siris; Nelson B Watts; Michael J Miller; Jeffrey R Curtis; Amy H Warriner; Nicole C Wright; Kenneth G Saag
Journal:  J Bone Miner Res       Date:  2018-02-26       Impact factor: 6.741

3.  Effective secondary fracture prevention: implementation of a global benchmarking of clinical quality using the IOF Capture the Fracture® Best Practice Framework tool.

Authors:  M K Javaid; C Kyer; P J Mitchell; J Chana; C Moss; M H Edwards; A R McLellan; J Stenmark; D D Pierroz; M C Schneider; J A Kanis; K Akesson; C Cooper
Journal:  Osteoporos Int       Date:  2015-06-13       Impact factor: 4.507

4.  Treatment pattern in postmenopausal women with osteoporosis: a population-based cohort study in South Korea.

Authors:  Ju Hwan Kim; Han Eol Jeong; Yeon-Hee Baek; Sun Wook Cho; Hyuna Lim; Ju-Young Shin
Journal:  J Bone Miner Metab       Date:  2021-08-23       Impact factor: 2.626

5.  Are Nursing Home Residents With Dementia Appropriately Treated for Fracture Prevention?

Authors:  Joshua D Niznik; Xintong Li; Meredith A Gilliam; Laura C Hanson; Sherrie L Aspinall; Cathleen Colon-Emeric; Carolyn T Thorpe
Journal:  J Am Med Dir Assoc       Date:  2020-12-13       Impact factor: 7.802

6.  Association of gastrointestinal events and osteoporosis treatment initiation in newly diagnosed osteoporotic Israeli women.

Authors:  J Yu; I Goldshtein; V Shalev; G Chodick; S Ish-Shalom; O Sharon; A Modi
Journal:  Int J Clin Pract       Date:  2015-08-17       Impact factor: 2.503

7.  Dementia is Associated with an Increased Risk of Hip Fractures: A Nationwide Analysis in Korea.

Authors:  Jae Hyuen Jeon; Jeong Hoon Park; Chungkun Oh; Jae Kyung Chung; Jeong Yun Song; Seongheon Kim; Seung Hwan Lee; Jae Won Jang; Young Ju Kim
Journal:  J Clin Neurol       Date:  2019-04       Impact factor: 3.077

8.  Increased risk of hip fractures in patients with dementia: a nationwide population-based study.

Authors:  Hao-Kuang Wang; Chao-Ming Hung; Sheng-Hsiang Lin; Yi-Cheng Tai; Kang Lu; Po-Chou Liliang; Chi-Wei Lin; Yi-Che Lee; Pei-Hsuan Fang; Li-Ching Chang; Ying-Chun Li
Journal:  BMC Neurol       Date:  2014-09-12       Impact factor: 2.474

9.  Undertreatment of osteoporosis and the role of gastrointestinal events among elderly osteoporotic women with Medicare Part D drug coverage.

Authors:  Ethel S Siris; Jingbo Yu; Katalin Bognar; Mitch DeKoven; Anshu Shrestha; John A Romley; Ankita Modi
Journal:  Clin Interv Aging       Date:  2015-11-05       Impact factor: 4.458

10.  Predictors of falls and fractures leading to hospitalisation in 36 101 people with affective disorders: a large representative cohort study.

Authors:  Ruimin Ma; Gayan Perera; Eugenia Romano; Davy Vancampfort; Ai Koyanagi; Robert Stewart; Christoph Mueller; Brendon Stubbs
Journal:  BMJ Open       Date:  2022-03-11       Impact factor: 2.692

  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.