Literature DB >> 20398147

Missed opportunities for osteoporosis treatment in patients hospitalized for hip fracture.

Lee A Jennings1, Andrew D Auerbach, Judith Maselli, Penelope S Pekow, Peter K Lindenauer, Sei J Lee.   

Abstract

OBJECTIVES: Although osteoporosis treatment can dramatically reduce fracture risk, rates of treatment after hip fracture remain low. In-hospital initiation of recommended medications has improved outcomes in heart disease; hospitalization for hip fracture may represent a similar opportunity for improvement. The objective of this study was to examine rates of in-hospital treatment with a combination of calcium and vitamin D (Cal+D) and antiresorptive or bone-forming medications in patients hospitalized for hip fractures
DESIGN: Observational cohort.
SETTING: Three hundred eighteen hospitals in the United States. PARTICIPANTS: Fifty-one thousand three hundred forty-six patients aged 65 and older hospitalized for osteoporotic hip fracture. MEASUREMENTS: In-hospital administration of Cal+D and antiresorptive or bone-forming medications.
RESULTS: Three thousand four hundred five patients (6.6%) received Cal+D anytime after a procedure to correct femoral fracture; 3,763 patients (7.3%) received antiresorptive or bone-forming medications. Only 1,023 patients (2.0%) were prescribed ideal therapy, receiving Cal+D and an antiresorptive or bone-forming medication. Treatment rates remained low across virtually all patient-, provider-, and hospital-level characteristics. The strongest predictor of treatment with Cal+D was the receipt of an antiresorptive or bone-forming medication (adjusted odds ratio=5.50, 95% confidence interval=4.84-6.25), but only 27.2% of patients who received these medications also received Cal+D.
CONCLUSION: Rates of in-hospital initiation of osteoporosis treatment for patients with hip fracture are low and may represent an opportunity to improve care.

Entities:  

Keywords:  Calcium; Hip Fracture; Osteoporosis; Vitamin D

Mesh:

Substances:

Year:  2010        PMID: 20398147      PMCID: PMC2858360          DOI: 10.1111/j.1532-5415.2010.02769.x

Source DB:  PubMed          Journal:  J Am Geriatr Soc        ISSN: 0002-8614            Impact factor:   5.562


  41 in total

1.  A single systemic dose of pamidronate improves bone mineral content and accelerates restoration of strength in a rat model of fracture repair.

Authors:  Negin Amanat; Richard Brown; Lynne E Bilston; David G Little
Journal:  J Orthop Res       Date:  2005-04-19       Impact factor: 3.494

2.  Use of a case manager to improve osteoporosis treatment after hip fracture: results of a randomized controlled trial.

Authors:  Sumit R Majumdar; Lauren A Beaupre; Charles H Harley; David A Hanley; Douglas A Lier; Angela G Juby; Walter P Maksymowych; John G Cinats; Neil R Bell; Donald W Morrish
Journal:  Arch Intern Med       Date:  2007-10-22

3.  Trends in drug prescribing for osteoporosis after hip fracture, 1995-2004.

Authors:  Suzanne M Cadarette; Jeffrey N Katz; M Alan Brookhart; Raisa Levin; Margaret R Stedman; Niteesh K Choudhry; Daniel H Solomon
Journal:  J Rheumatol       Date:  2007-12-01       Impact factor: 4.666

Review 4.  Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older: a meta-analysis.

Authors:  Benjamin M P Tang; Guy D Eslick; Caryl Nowson; Caroline Smith; Alan Bensoussan
Journal:  Lancet       Date:  2007-08-25       Impact factor: 79.321

5.  An outreach program improved osteoporosis management after a fracture.

Authors:  Adrianne C Feldstein; William M Vollmer; David H Smith; Amanda Petrik; Jennifer Schneider; Harry Glauber; Michael Herson
Journal:  J Am Geriatr Soc       Date:  2007-09       Impact factor: 5.562

6.  The American Orthopaedic Association's "own the bone" initiative to prevent secondary fractures.

Authors:  Laura L Tosi; Richard Gliklich; Krishna Kannan; Kenneth J Koval
Journal:  J Bone Joint Surg Am       Date:  2008-01       Impact factor: 5.284

7.  High-trauma fractures and low bone mineral density in older women and men.

Authors:  Dawn C Mackey; Li-Yung Lui; Peggy M Cawthon; Douglas C Bauer; Michael C Nevitt; Jane A Cauley; Teresa A Hillier; Cora E Lewis; Elizabeth Barrett-Connor; Steven R Cummings
Journal:  JAMA       Date:  2007-11-28       Impact factor: 56.272

8.  Effectiveness of antiresorptive agents in the prevention of recurrent hip fractures.

Authors:  S Morin; E Rahme; H Behlouli; A Tenenhouse; D Goltzman; L Pilote
Journal:  Osteoporos Int       Date:  2007-07-19       Impact factor: 4.507

9.  Systematic review: comparative effectiveness of treatments to prevent fractures in men and women with low bone density or osteoporosis.

Authors:  Catherine MacLean; Sydne Newberry; Margaret Maglione; Maureen McMahon; Veena Ranganath; Marika Suttorp; Walter Mojica; Martha Timmer; Alicia Alexander; Melissa McNamara; Sheetal B Desai; Annie Zhou; Susan Chen; Jason Carter; Carlo Tringale; Di Valentine; Breanne Johnsen; Jennifer Grossman
Journal:  Ann Intern Med       Date:  2007-12-17       Impact factor: 25.391

10.  Zoledronic acid and clinical fractures and mortality after hip fracture.

Authors:  Kenneth W Lyles; Cathleen S Colón-Emeric; Jay S Magaziner; Jonathan D Adachi; Carl F Pieper; Carlos Mautalen; Lars Hyldstrup; Chris Recknor; Lars Nordsletten; Kathy A Moore; Catherine Lavecchia; Jie Zhang; Peter Mesenbrink; Patricia K Hodgson; Ken Abrams; John J Orloff; Zebulun Horowitz; Erik Fink Eriksen; Steven Boonen
Journal:  N Engl J Med       Date:  2007-09-17       Impact factor: 91.245

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1.  [Geriatric traumatology--new treatments, new opportunities].

Authors:  Markus Gosch; Katharina Pils
Journal:  Z Gerontol Geriatr       Date:  2011-12       Impact factor: 1.281

2.  Secondary fracture prevention.

Authors:  Robert A Adler
Journal:  Curr Osteoporos Rep       Date:  2012-03       Impact factor: 5.096

3.  Medical management in the acute hip fracture patient: a comprehensive review for the internist.

Authors:  Laura Bateman; Srinivas Vuppala; Patricia Porada; William Carter; Charitraheen Baijnath; Kabeer Burman; Ryan Lee; Jodie Hargus
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4.  Undertreatment of osteoporosis in persons with dementia? A population-based study.

Authors:  Y Haasum; J Fastbom; L Fratiglioni; K Johnell
Journal:  Osteoporos Int       Date:  2011-04-16       Impact factor: 4.507

Review 5.  [Management of osteoporosis after fragility fractures].

Authors:  M Gosch; U Stumpf; C Kammerlander; W Böcker; H J Heppner; S Wicklein
Journal:  Z Gerontol Geriatr       Date:  2018-01-05       Impact factor: 1.281

6.  CORR Insights®: A Resident-led Initiative Improves Screening and Treatment for Vitamin D Deficiency in Patients with Hip Fractures.

Authors:  Kimberly J Templeton
Journal:  Clin Orthop Relat Res       Date:  2016-10-26       Impact factor: 4.176

7.  Quality of osteoporosis care of older Medicare recipients with fragility fractures: 2006 to 2010.

Authors:  Stephen K Liu; Jeffrey C Munson; John-Erik Bell; Rebecca L Zaha; John N Mecchella; Anna N A Tosteson; Nancy E Morden
Journal:  J Am Geriatr Soc       Date:  2013-10-28       Impact factor: 5.562

8.  Non-linear relationship between serum 25-hydroxyvitamin D concentration and subsequent hip fracture.

Authors:  L de Koning; D Henne; B R Hemmelgarn; P Woods; C Naugler
Journal:  Osteoporos Int       Date:  2012-12-19       Impact factor: 4.507

Review 9.  Management of osteoporosis in patients hospitalized for hip fractures.

Authors:  T P Ip; J Leung; A W C Kung
Journal:  Osteoporos Int       Date:  2010-11-06       Impact factor: 4.507

10.  Evaluation of a Multimodal, Direct-to-Patient Educational Intervention Targeting Barriers to Osteoporosis Care: A Randomized Clinical Trial.

Authors:  Maria I Danila; Ryan C Outman; Elizabeth J Rahn; Amy S Mudano; David T Redden; Peng Li; Jeroan J Allison; Fred A Anderson; Allison Wyman; Susan L Greenspan; Andrea Z LaCroix; Jeri W Nieves; Stuart L Silverman; Ethel S Siris; Nelson B Watts; Michael J Miller; Jeffrey R Curtis; Amy H Warriner; Nicole C Wright; Kenneth G Saag
Journal:  J Bone Miner Res       Date:  2018-02-26       Impact factor: 6.741

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