Literature DB >> 23525513

Node-positive left-sided breast cancer: does VMAT improve treatment plan quality with respect to IMRT?

M Pasler1, D Georg, S Bartelt, J Lutterbach.   

Abstract

PURPOSE: The aim of the present work was to explore plan quality and dosimetric accuracy of intensity-modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) for lymph node-positive left-sided breast cancer.
METHODS: VMAT and IMRT plans were generated with the Pinnacle(3) V9.0 treatment planning system for 10 lymph node-positive left-sided breast cancer patients. VMAT plans were created using a single arc and IMRT was performed with 4 beams using 6, 10, and 15 MV photon energy, respectively. Plans were evaluated both manually and automatically using ArtiView™. Dosimetric plan verification was performed with a 2D ionization chamber array placed in a full scatter phantom.
RESULTS: Photon energy had no significant influence on plan quality for both VMAT and IMRT. Large variability in low doses to the heart was found due to patient anatomy (range V(5 Gy) 26.5-95 %). Slightly more normal tissue dose was found for VMAT (e.g., V(Tissue30%) = 22 %) than in IMRT (V(Tissue30%) = 18 %). The manual and ArtiView™ plan evaluation coincided very accurately for most dose metrics (difference < 1 %). In VMAT, 96.7 % of detector points passed the 3 %/3 mm gamma criterion; marginally better accuracy was found in IMRT (98.3 %).
CONCLUSION: VMAT for node-positive left-sided breast cancer retains target homogeneity and coverage when compared to IMRT and allows maximum doses to organs at risk to be reduced. ArtiView™ enables fast and accurate plan evaluation.

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Mesh:

Year:  2013        PMID: 23525513     DOI: 10.1007/s00066-012-0281-2

Source DB:  PubMed          Journal:  Strahlenther Onkol        ISSN: 0179-7158            Impact factor:   3.621


  34 in total

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Journal:  Int J Radiat Oncol Biol Phys       Date:  2012-06-05       Impact factor: 7.038

4.  Interpretation and evaluation of the gamma index and the gamma index angle for the verification of IMRT hybrid plans.

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Journal:  Phys Med Biol       Date:  2005-02-07       Impact factor: 3.609

5.  A treatment planning study using non-coplanar static fields and coplanar arcs for whole breast radiotherapy of patients with concave geometry.

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6.  Pulmonary complications following different radiotherapy techniques for breast cancer, and the association to irradiated lung volume and dose.

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8.  [Inversely planned intensity modulated radiotherapy for irradiation of a woman with breast cancer and funnel chest].

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Review 9.  [Is cardiotoxicity still an issue after breast-conserving surgery and could it be reduced by multifield IMRT?].

Authors:  Frank Lohr; Felix Heggemann; Theano Papavassiliu; Mostafa El-Haddad; Oliver Tomé; Dietmar Dinter; Barbara Dobler; Uta Kraus-Tiefenbacher; Martin Borggrefe; Frederik Wenz
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Journal:  Strahlenther Onkol       Date:  2008-02       Impact factor: 3.621

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  19 in total

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2.  Incidental dose to coronary arteries is higher in prone than in supine whole breast irradiation. A dosimetric comparison in adjuvant radiotherapy of early stage breast cancer.

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4.  Heart dose reduction in breast cancer treatment with simultaneous integrated boost: Comparison of treatment planning and dosimetry for a novel hybrid technique and 3D-CRT.

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5.  Volumetric intensity-modulated arc therapy vs. 3-dimensional conformal radiotherapy for primary chemoradiotherapy of anal carcinoma: Effects on treatment-related side effects and survival.

Authors:  Hanne Elisabeth Weber; Leif Hendrik Dröge; Steffen Hennies; Markus Karl Herrmann; Jochen Gaedcke; Hendrik Andreas Wolff
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6.  Late inflammatory and thrombotic changes in irradiated hearts of C57BL/6 wild-type and atherosclerosis-prone ApoE-deficient mice.

Authors:  I Patties; J Haagen; W Dörr; G Hildebrandt; A Glasow
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8.  A comparative dosimetric study of left sided breast cancer after breast-conserving surgery treated with VMAT and IMRT.

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9.  An IMRT/VMAT Technique for Nonsmall Cell Lung Cancer.

Authors:  Nan Zhao; Ruijie Yang; Junjie Wang; Xile Zhang; Jinna Li
Journal:  Biomed Res Int       Date:  2015-10-11       Impact factor: 3.411

10.  Evaluation of Auto-Planning for Left-Side Breast Cancer After Breast-Conserving Surgery Based on Geometrical Relationship.

Authors:  Yijiang Li; Han Bai; Danju Huang; Feihu Chen; Yaoxiong Xia
Journal:  Technol Cancer Res Treat       Date:  2021 Jan-Dec
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