Literature DB >> 2351177

An evaluation of 99mTc-HMPAO uptake in cerebral gliomas--a comparison with X-ray CT.

A T Irvine1, M A Flower, R J Ott, J W Babich, F Kabir, V R McCready.   

Abstract

Nineteen patients with biopsy-proven cerebral gliomas were studied with 99mTc-HMPAO single photon emission tomography (SPECT) imaging and X-ray computed tomography (CT). The uptake of 99mTc-HMPAO was correlated with tumour size and morphology as shown by X-ray CT, and overall patient survival. It appears that uptake of 99mTc-HMPAO is associated with larger, ill-defined tumours and was an adverse factor in patient survival. In those tumours with normal or increased uptake, 99mTc-HMPAO imaging is useful in distinguishing the tumour margin from surrounding oedema.

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Year:  1990        PMID： 2351177     DOI： 10.1007/bf00842782

Source DB:  PubMed          Journal:  Eur J Nucl Med        ISSN： 0340-6997


  10 in total

1.  Regional cerebral blood flow in patients with intracranial tumors.

Authors:  R Pálvölgyi
Journal:  J Neurosurg       Date:  1969-08       Impact factor: 5.115

2.  Development of I-123-labeled amines for brain studies: localization of I-123 iodophenylalkyl amines in rat brain.

Authors:  H S Winchell; R M Baldwin; T H Lin
Journal:  J Nucl Med       Date:  1980-10       Impact factor: 10.057

3.  Quantitative measurements of regional cerebral blood flow related to neuroradiological findings.

Authors:  S Cronqvist; D H Ingvar; N A Lassen
Journal:  Acta Radiol Diagn (Stockh)       Date:  1966

4.  Development of a 99Tcm-labelled radiopharmaceutical for cerebral blood flow imaging.

Authors:  D P Nowotnik; L R Canning; S A Cumming; R C Harrison; B Higley; G Nechvatal; R D Pickett; I M Piper; V J Bayne; A M Forster
Journal:  Nucl Med Commun       Date:  1985-09       Impact factor: 1.690

5.  Cerebral and cerebellar uptake of 99mTc-(d,1)-hexamethyl-propyleneamine oxime (HM-PAO) in patients with brain tumor studied by single photon emission computerized tomography.

Authors:  M W Lindegaard; A Skretting; B Hager; K Watne; K F Lindegaard
Journal:  Eur J Nucl Med       Date:  1986

6.  Tomographic studies of rCBF with 99mTc-HM-PAO SPECT in comparison with PET in patients with primary brain tumors.

Authors:  K J Langen; H Herzog; E Rota; N Roosen; H Wieler; J Kiwit; T Kuwert; A Storch-Becker; L Feinendegen
Journal:  Neurosurg Rev       Date:  1987       Impact factor: 3.042

7.  Technetium-99m d,l-HM-PAO: a new radiopharmaceutical for SPECT imaging of regional cerebral blood perfusion.

Authors:  R D Neirinckx; L R Canning; I M Piper; D P Nowotnik; R D Pickett; R A Holmes; W A Volkert; A M Forster; P S Weisner; J A Marriott
Journal:  J Nucl Med       Date:  1987-02       Impact factor: 10.057

8.  Initial experience with Tc-99m-HM-PAO in the study of brain tumors.

Authors:  J W Babich; F Keeling; M A Flower; L Repetto; A Whitton; S Fielding; A Fullbrook; R J Ott; V R McCready
Journal:  Eur J Nucl Med       Date:  1988

9.  Topographic anatomy and CT correlations in the untreated glioblastoma multiforme.

Authors:  P C Burger; E R Heinz; T Shibata; P Kleihues
Journal:  J Neurosurg       Date:  1988-05       Impact factor: 5.115

10.  A new brain perfusion imaging agent: [I-123]HIPDM:N,N,N'-trimethyl-N'-[2-hydroxy-3-methyl-5-iodobenzyl]-1,3-propanediamine.

Authors:  H F Kung; K M Tramposch; M Blau
Journal:  J Nucl Med       Date:  1983-01       Impact factor: 10.057
  10 in total
  2 in total

1.  Single photon emission computed tomography using 201Tl chloride in pulmonary nodules: comparison with 67Ga citrate and 99mTc-labeled hexamethylpropyleneamine-oxime.

Authors:  K Itoh; H Takekawa; E Tsukamoto; K Nagao; K Nakada; S Abe; Y Kawakami; M Furudate
Journal:  Ann Nucl Med       Date:  1992-11       Impact factor: 2.668

2.  Radiation effects on uptake of 99Tcm-hexamethylpropylen amine oxime (HMPAO) in head and neck tumours.

Authors:  H Minn; A Ahonen; R Paul
Journal:  Br J Cancer       Date:  1991-10       Impact factor: 7.640
  2 in total

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