| Literature DB >> 23507136 |
J Head1, S A Stansfeld, K P Ebmeier, J R Geddes, C L Allan, G Lewis, M Kivimäki.
Abstract
BACKGROUND: Diagnosis of depressive disorder using interviewer-administered instruments is expensive and frequently impractical in large epidemiological surveys. The aim of this study was to assess the validity of three self-completion measures of depressive disorder and other psychiatric disorders in older people against an interviewer-administered instrument.Entities:
Mesh:
Year: 2013 PMID: 23507136 PMCID: PMC3821376 DOI: 10.1017/S0033291713000342
Source DB: PubMed Journal: Psychol Med ISSN: 0033-2917 Impact factor: 7.723
Prevalence of mental disorders
| Prevalence ( | Weighted prevalence ( | Prevalence in cohort subsample ( | ||
|---|---|---|---|---|
| No. of cases | % (95% CI) | % (95% CI) | % (95% CI) | |
| CIS-R Any mental disorder | ||||
| Interview | 27 | 9.9 (6.3–13.4) | 5.9 (3.5–9.8) | 5.6 (2.5–8.7) |
| Self-completion | 24 | 8.8 (5.4–12.1) | 4.9 (2.8–8.6) | 4.7 (1.8–7.5) |
| CIS-R Specific disorders | ||||
| Depressive episode (F32) | ||||
| Interview | 12 | 4.4 (1.9–6.8) | 3.8 (1.9–7.3) | 3.7 (1.2–6.3) |
| Self-completion | 15 | 5.5 (2.8–8.2) | 3.4 (1.7–6.8) | 3.3 (0.9–5.7) |
| Mixed anxiety and depressive disorder (F41.2) | ||||
| Interview | 9 | 3.3 (1.2–5.4) | 1.5 (0.5–4.2) | 1.4 (0.1–3.0) |
| Self-completion | 6 | 2.2 (0.4–3.9) | 1.0 (0.3–3.6) | 0.9 (0.1–2.2) |
| Generalized anxiety disorder (F41.1) | ||||
| Interview | 16 | 5.8 (3.0–8.6) | 4.7 (2.6–8.5) | 4.7 (1.8–7.5) |
| Self-completion | 11 | 4.0 (1.7–6.3) | 2.4 (1.1–5.5) | 2.3 (0.3–4.4) |
| All phobias (F40) | ||||
| Interview | 5 | 1.8 (0.2–3.4) | 1.0 (0.3–3.6) | 0.9 (0.1–2.2) |
| Self-completion | 9 | 3.3 (1.2–5.4) | 1.5 (0.5–4.2) | 1.4 (0.1–3.0) |
| ( | ( | ( | ||
| CES-D case | 43 | 16.8 (12.2–21.4) | 10.7 (7.2–15.6) | 10.3 (6.1–14.5) |
| GHQ case | 49 | 19.1 (14.3–24.0) | 15.0 (10.7–20.5) | 14.7 (9.8–19.6) |
| GHQ depression case | 21 | 8.2 (4.8–11.6) | 6.0 (3.5–10.2) | 5.9 (2.6–9.1) |
CIS-R, Clinical Interview Schedule Revised; CI, confidence interval; CES-D, Center for Epidemiologic Studies Depression Scale; GHQ, General Health Questionnaire.
There were two cases of panic disorder (ICD-10 F41.0) and no cases of obsessive–compulsive disorder (ICD-10 F42).
Agreement between self-completion and interviewer versions for the total CIS-R score and symptom scores (n = 274)
| Mean self-completion | Mean interview | Difference in means | 95% CI for difference in means | Weighted | |
|---|---|---|---|---|---|
| Total CIS-R score | 4.35 | 4.43 | −0.08 | −0.31 to 0.16 | 0.94 |
| Symptom scores | |||||
| Somatic | 0.23 | 0.14 | 0.08 | −0.01 to 0.18 | 0.31 |
| Fatigue | 0.51 | 0.59 | −0.08 | −0.16 to −0.01 | 0.81 |
| Concentration and forgetfulness | 0.31 | 0.31 | 0 | −0.05 to 0.05 | 0.77 |
| Sleep | 0.86 | 0.91 | −0.05 | −0.12 to 0.02 | 0.87 |
| Irritability | 0.36 | 0.32 | 0.04 | −0.01 to 0.09 | 0.78 |
| Worry over physical health | 0.26 | 0.30 | −0.04 | −0.09 to 0.01 | 0.76 |
| Depression | 0.23 | 0.19 | 0.04 | −0.01 to 0.10 | 0.71 |
| Depressive ideas | 0.20 | 0.15 | 0.05 | 0.01 to 0.10 | 0.84 |
| Worry | 0.50 | 0.61 | −0.11 | −0.18 to 0.03 | 0.79 |
| Anxiety | 0.27 | 0.30 | −0.04 | −0.11 to 0.04 | 0.62 |
| Phobias | 0.14 | 0.10 | 0.03 | −0.01 to 0.07 | 0.80 |
| Panic | 0.03 | 0.03 | 0 | −0.01 to 0.01 | 0.94 |
| Compulsions | 0.17 | 0.24 | −0.07 | −0.13 to −0.01 | 0.69 |
| Obsessions | 0.29 | 0.24 | 0.05 | −0.03 to 0.13 | 0.56 |
CIS-R, Clinical Interview Schedule Revised; CI, confidence interval.
Total score ranges from 0 to 57.
Symptom scores range from 0 to 4 (depressive ideas symptom score 0 to 5).
Sensitivity and specificity for the self-completion CIS-R assessment of mental disorders with the interviewer-administered CIS-R as the criterion (n = 274)
| No. of cases Interviewer/self-completion | Sensitivity% (95% CI) | Specificity% (95% CI) | +PV | −PV | +LR | −LR | AUC (95% CI) | ||
|---|---|---|---|---|---|---|---|---|---|
| Any mental disorder | 27/24 | 0.37 | 74.1 (0.53–0.88) | 98.4 (0.96–0.99) | 0.83 | −0.97 | 45.74 | 0.26 | 0.86 (0.78–0.95) |
| Specific disorders (ICD-10 code) | |||||||||
| Depressive episode (F32) | 12/15 | 0.32 | 75.0 (0.43–0.97) | 97.7 (0.95–0.99) | 0.60 | 0.99 | 32.75 | 0.26 | 0.86 (0.74–0.99) |
| Mixed anxiety and depressive disorder (F41.2) | 9/6 | 0.41 | 11.1 (0.01–0.49) | 98.1 (0.95–0.99) | 0.17 | 0.97 | 5.89 | 0.91 | 0.55 (0.44–0.66) |
| Generalized anxiety disorder (F41.1) | 16/11 | 0.20 | 37.5 (0.16–0.64) | 98.1 (0.95–0.99) | 0.56 | 0.96 | 19.35 | 0.64 | 0.68 (0.56–0.80) |
| All phobias (F40) | 5/9 | 0.10 | 80.0 (0.30–0.99) | 98.1 (0.95–0.99) | 0.44 | 0.99 | 43.04 | 0.20 | 0.89 (0.69–0.99) |
CIS-R, Clinical Interview Schedule Revised; CI, confidence interval; +PV, positive predictive value; −PV, negative predictive value; +LR, positive likelihood ratio; −LR, negative likelihood ratio; AUC, area under the receiver operating characteristic (ROC) curve.
McNemar's χ2 test for difference in prevalence between interviewer and self-completion versions.
Sensitivity and specificity for the self-completion CES-D and the GHQ as measures of any mental disorder and depressive episode with the interviewer-administered CIS-R as the criterion (n = 256)
| CIS-R interviewer version | +PV | −PV | +LR | −LR | AUC (95% CI) | ||
|---|---|---|---|---|---|---|---|
| Sensitivity (%) | Specificity (%) | ||||||
| Any mental disorder | |||||||
| CES-D case | 77.3 (0.54–0.91) | 88.9 (0.84–0.92) | 0.39 | 0.98 | 6.95 | 0.26 | 0.83 (0.74–0.92) |
| GHQ case | 86.4 (0.64–0.96) | 87.2 (0.82–0.91) | 0.39 | 0.99 | 6.74 | 0.16 | 0.87 (0.79–0.94) |
| GHQ depression case | 36.4 (0.18–0.59) | 94.4 (0.80–0.97) | 0.38 | 0.94 | 6.55 | 0.67 | 0.65 (0.55–0.76) |
| Depressive episode | |||||||
| CES-D case | 88.9 (0.51–0.99) | 85.8 (0.81–0.90) | 0.19 | 0.99 | 6.27 | 0.13 | 0.87 (0.76–0.98) |
| GHQ case | 77.8 (0.40–0.96) | 83.0 (0.78–0.87) | 0.14 | 0.99 | 4.57 | 0.27 | 0.80 (0.66–0.95) |
| GHQ depression case | 44.4 (0.15–0.77) | 93.1 (0.89–0.96) | 0.19 | 0.98 | 6.46 | 0.60 | 0.69 (0.51–0.86) |
CES-D, Center for Epidemiologic Studies Depression Scale; GHQ, General Health Questionnaire; CIS-R, Clinical Interview Schedule Revised; +PV, positive predictive value; −PV, negative predictive value; +LR, positive likelihood ratio; −LR, negative likelihood ratio; AUC, area under the receiver operating characteristic (ROC) curve; CI, confidence interval.