Literature DB >> 23413388

The epidemiology of osteoporosis--Bone Evaluation Study (BEST): an analysis of routine health insurance data.

Peyman Hadji1, Silvia Klein, Holger Gothe, Bertram Häussler, Thomas Kless, Torsten Schmidt, Thomas Steinle, Frank Verheyen, Roland Linder.   

Abstract

BACKGROUND: Osteoporosis is a widespread disease of the skeleton that becomes more common with advancing age. Its prevalence is still inadequately documented. The goal of this study is to determine how common osteoporosis is in Germany.
METHODS: The routine billing data of a large statutory health insurance carrier in Germany (the TK company) from the years 2006 to 2009 were anonymized and retrospectively analyzed. Insurees aged 50 and above with osteoporosis were identified either from their bearing the diagnosis of osteoporosis or of osteoporosis-related fractures, or from their having received prescription medication for osteoporosis. The prevalence and incidence of osteoporosis and the frequency of osteoporotic fractures were calculated for TK insurees and extrapolated to the overall German population.
RESULTS: The prevalence of osteoporosis among persons aged 50 and above, as revealed by diagnoses of osteoporosis or osteoporotic fractures, or by the prescription of medication for osteoporosis, was found to be 14% (240,657 of 1.7 million insurees) in the year 2009; the sex-specific prevalence was 24% in women and 6% in men. An extrapolation of these figures implies that 6.3 million persons in Germany have osteoporosis. The incidence of osteoporosis in the same age group, as revealed by a diagnosis of osteoporosis or prescription of medication for osteoporosis, was found to be 2.1% per year, with 104,528 insurees having an index event for osteoporosis (initial diagnosis of osteoporosis or first prescription of a medication for osteoporosis). An extrapolation of this figure implies that 885,000 persons newly develop osteoporosis in Germany each year. Over the period of observation, 52% of the affected persons (total, 172,473 persons) sustained fractures, many of which were multiple.
CONCLUSION: Osteoporosis is still common in Germany. The large number of insurees with single and multiple fractures implies that the treatment of this disease in Germany needs to be improved.

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Year:  2013        PMID: 23413388      PMCID: PMC3570954          DOI: 10.3238/arztebl.2013.0052

Source DB:  PubMed          Journal:  Dtsch Arztebl Int        ISSN: 1866-0452            Impact factor:   5.594


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1.  [Structural differences between health insurance funds and their impact on health services research: results from the Bertelsmann Health-Care Monitor].

Authors:  F Hoffmann; A Icks
Journal:  Gesundheitswesen       Date:  2011-07-13

2.  The health and economic consequences of osteopenia- and osteoporosis-attributable hip fractures in Germany: estimation for 2002 and projection until 2050.

Authors:  A Konnopka; N Jerusel; H-H König
Journal:  Osteoporos Int       Date:  2008-12-02       Impact factor: 4.507

3.  Epidemiology, treatment and costs of osteoporosis in Germany--the BoneEVA Study.

Authors:  B Häussler; H Gothe; D Göl; G Glaeske; L Pientka; D Felsenberg
Journal:  Osteoporos Int       Date:  2006-09-19       Impact factor: 4.507

4.  Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025.

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5.  [Epidemiology of limb fractures].

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6.  Impact of prevalent fractures on quality of life: baseline results from the global longitudinal study of osteoporosis in women.

Authors:  Jonathan D Adachi; Silvano Adami; Stephen Gehlbach; Frederick A Anderson; Steven Boonen; Roland D Chapurlat; Juliet E Compston; Cyrus Cooper; Pierre Delmas; Adolfo Díez-Pérez; Susan L Greenspan; Frederick H Hooven; Andrea Z LaCroix; Robert Lindsay; J Coen Netelenbos; Olivia Wu; Johannes Pfeilschifter; Christian Roux; Kenneth G Saag; Philip N Sambrook; Stuart Silverman; Ethel S Siris; Grigor Nika; Nelson B Watts
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7.  A model of lifetime osteoporosis impact.

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8.  Burden of hip fracture on inpatient care: a before and after population-based study.

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9.  Health-related quality of life in patients with osteopenia or osteoporosis with and without fractures in a geriatric rehabilitation department.

Authors:  Barbara Jahelka; Thomas Dorner; Robert Terkula; Michael Quittan; Hans Bröll; Ludwig Erlacher
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Review 10.  Perspective. How many women have osteoporosis?

Authors:  L J Melton; E A Chrischilles; C Cooper; A W Lane; B L Riggs
Journal:  J Bone Miner Res       Date:  1992-09       Impact factor: 6.741

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1.  Balloon kyphoplasty of T8 in an osteoporotic fracture.

Authors:  Marie-Therese Unterweger; Klaus John Schnake
Journal:  Eur Spine J       Date:  2015-12       Impact factor: 3.134

2.  Correspondence (letter to the editor): Paradigm shift.

Authors:  Peter Schneider
Journal:  Dtsch Arztebl Int       Date:  2013-05       Impact factor: 5.594

3.  Correspondence (reply): In reply.

Authors:  Peyman Hadji; Silvia Klein
Journal:  Dtsch Arztebl Int       Date:  2013-05       Impact factor: 5.594

Review 4.  [Management of osteoporosis after fragility fractures].

Authors:  M Gosch; U Stumpf; C Kammerlander; W Böcker; H J Heppner; S Wicklein
Journal:  Z Gerontol Geriatr       Date:  2018-01-05       Impact factor: 1.281

5.  A pedicle screw system and a lamina hook system provide similar primary and long-term stability: a biomechanical in vitro study with quasi-static and dynamic loading conditions.

Authors:  Hans-Joachim Wilke; Dominik Kaiser; David Volkheimer; Carsten Hackenbroch; Klaus Püschel; Michael Rauschmann
Journal:  Eur Spine J       Date:  2016-07-12       Impact factor: 3.134

6.  Increased treatment persistence and its determinants in women with osteoporosis with prior fracture compared to those without fracture.

Authors:  L Jacob; M Dreher; K Kostev; P Hadji
Journal:  Osteoporos Int       Date:  2015-10-30       Impact factor: 4.507

Review 7.  [Regulation of bone metabolism in osteoporosis : novel drugs for osteoporosis in development].

Authors:  F Jakob; F Genest; G Baron; U Stumpf; M Rudert; L Seefried
Journal:  Unfallchirurg       Date:  2015-11       Impact factor: 1.000

8.  [Osteomalacia-Clinical aspects, diagnostics and treatment].

Authors:  M Tiefenbach; M Scheel; A Maier; M Gehlen; M Schwarz-Eywill; M Werner; U Siebers-Renelt; M Hammer
Journal:  Z Rheumatol       Date:  2018-10       Impact factor: 1.372

9.  The non-interventional BonViva Intravenous Versus Alendronate (VIVA) study: real-world adherence and persistence to medication, efficacy, and safety, in patients with postmenopausal osteoporosis.

Authors:  P Hadji; D Felsenberg; M Amling; L C Hofbauer; J A Kandenwein; A Kurth
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Review 10.  [Proximal femoral fractures in the elderly].

Authors:  Carl Neuerburg; M Gosch; W Böcker; M Blauth; C Kammerlander
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