Literature DB >> 23401304

Engineering new protein-protein interactions on the β-propeller fold by yeast cell surface display.

Keya Zhang1, Heng Li, Karan Bhuripanyo, Bo Zhao, Tiffany F Chen, Ning Zheng, Jun Yin.   

Abstract

REINVENTING THE WHEEL: The β-propeller domain folds like a wheel to provide key protein-protein interactions in the cell. Here we used high-throughput yeast sorting to "invent" β-propellers of new binding specificities with cellular targets.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2013        PMID: 23401304      PMCID: PMC3822001          DOI: 10.1002/cbic.201200718

Source DB:  PubMed          Journal:  Chembiochem        ISSN: 1439-4227            Impact factor:   3.164


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