Mathias Engström1, Stefan Skare. 1. Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Department of Neuroradiology, Karolinska University Hospital, Stockholm, Sweden.
Abstract
PURPOSE: To acquire isotropic high-resolution, signal-to-noise ratio (SNR) efficient, 3D encoded diffusion-weighted MRI data. METHODS: Multiple Fourier encoded slabs were combined into one full volume, using a generalized autocalibrating partially parallel acquisitions (GRAPPA) accelerated diffusion-weighted 3D multislab echo planar imaging (EPI) sequence with 2D phase navigation and in-plane motion correction. RESULTS: Reconstructed data with 1.5-mm(3) nominal resolution is presented and shown under the influence of motion and with variable slab thicknesses. The SNR efficiency between diffusion-weighted 3D multislab EPI and DW 2D ss-EPI is compared. Finally, a 1.3-mm(3) full brain scan with 45 diffusion directions is presented. CONCLUSIONS: Diffusion-weighted 3D multislab EPI has been presented as an alternative sequence for high-resolution and high-SNR full brain coverage diffusion studies. Compared with the gold standard 2D diffusion-weighted single-shot Echo Planar Imaging, the SNR efficiency is significantly higher.
PURPOSE: To acquire isotropic high-resolution, signal-to-noise ratio (SNR) efficient, 3D encoded diffusion-weighted MRI data. METHODS: Multiple Fourier encoded slabs were combined into one full volume, using a generalized autocalibrating partially parallel acquisitions (GRAPPA) accelerated diffusion-weighted 3D multislab echo planar imaging (EPI) sequence with 2D phase navigation and in-plane motion correction. RESULTS: Reconstructed data with 1.5-mm(3) nominal resolution is presented and shown under the influence of motion and with variable slab thicknesses. The SNR efficiency between diffusion-weighted 3D multislab EPI and DW 2D ss-EPI is compared. Finally, a 1.3-mm(3) full brain scan with 45 diffusion directions is presented. CONCLUSIONS: Diffusion-weighted 3D multislab EPI has been presented as an alternative sequence for high-resolution and high-SNR full brain coverage diffusion studies. Compared with the gold standard 2D diffusion-weighted single-shot Echo Planar Imaging, the SNR efficiency is significantly higher.
Authors: Kawin Setsompop; Qiuyun Fan; Jason Stockmann; Berkin Bilgic; Susie Huang; Stephen F Cauley; Aapo Nummenmaa; Fuyixue Wang; Yogesh Rathi; Thomas Witzel; Lawrence L Wald Journal: Magn Reson Med Date: 2017-03-05 Impact factor: 4.668
Authors: Congyu Liao; Jason Stockmann; Qiyuan Tian; Berkin Bilgic; Nicolas S Arango; Mary Kate Manhard; Susie Y Huang; William A Grissom; Lawrence L Wald; Kawin Setsompop Journal: Magn Reson Med Date: 2019-08-01 Impact factor: 4.668
Authors: Sjoerd B Vos; Murat Aksoy; Zhaoying Han; Samantha J Holdsworth; Julian Maclaren; Max A Viergever; Alexander Leemans; Roland Bammer Journal: Neuroimage Date: 2016-01-14 Impact factor: 6.556