| Literature DB >> 23337221 |
Brendan Mulhern1, Louise Longworth, John Brazier, Donna Rowen, Nick Bansback, Nancy Devlin, Aki Tsuchiya.
Abstract
BACKGROUND: Health state valuation exercises can be conducted online, but the quality of data generated is unclear.Entities:
Mesh:
Year: 2013 PMID: 23337221 PMCID: PMC3556780 DOI: 10.1016/j.jval.2012.09.001
Source DB: PubMed Journal: Value Health ISSN: 1098-3015 Impact factor: 5.725
Fig. 1Basic binary choice question format used in the survey.
The 12 experimental questions used for the survey.
| L | |||||||
|---|---|---|---|---|---|---|---|
| I | Slight problems walking about | 10 y | n/m | You | n/m | Full health | 9 y |
| I | Slight pain | 10 wk | n/m | You | n/m | Full health | 8 wk |
| I | Unable to walk about | 10 y | n/m | You | n/m | Full health | 8 y |
| I | Extreme pain | 2 y | n/m | You | n/m | Full health | 5 y |
| I | Extremely depressed | 1 y | n/m | You | n/m | Full health | 7 mo |
| II | Extreme pain | 10 y | n/m | Somebody else | n/m | Full health | 6 y |
| III | Slight pain | 10 wk | 10 wk | You | n/m | Full health | 19 wk |
| IV | Extremely depressed | 1 y | 10 wk | Somebody else like you | n/m | Full health | 7 mo |
| V | Unable to walk about | 5 y | n/m | You | High | Full health | 3 y |
| VI | 55555 | 10 y | 10 yr | You | n/m | Immediate death | n/a |
| Subversion 1 | |||||||
| VIIa | 24144 | 5 y | n/m | You | n/m | 54514 | 1 y |
| VIIb | 53543 | 10 y | n/m | You | n/m | 31354 | 10 y |
| Subversion 2 | |||||||
| VIIc | 25555 | 1 y | n/m | You | n/m | 42424 | 1 y |
| VIId | 41234 | 1 y | n/m | You | n/m | 14112 | 1 y |
n/m, not mentioned in scenario.
EQ-5D-5L health state listed.
Sample characteristics.
| n | 422 | 221 (52.37) | 201 (47.63) | Matched | |||||
| Age | |||||||||
| Mean±SD | 41.49±13.96 | 41.56±14.38 | 41.41±13.52 | 42.23 | n/a | 0.913 | n/a | n/a | n/a |
| Range | 18–65 | 18–65 | 18–65 | 18–64 | |||||
| Age category, n (%) | 0.411 | 0.233 | 0.415 | 0.154 | 0.980 | ||||
| 18–24 | 64 (15.2) | 34 (15.4) | 30 (15.0) | 13.7 | |||||
| 25–34 | 97 (23.0) | 51 (23.1) | 46 (22.9) | 23.2 | |||||
| 35–44 | 85 (20.1) | 36 (16.29) | 49 (24.4) | 24.3 | |||||
| 45–54 | 86 (20.4) | 46 (21.8) | 40 (19.9) | 21.6 | |||||
| 55–64 | 90 (21.3) | 54 (24.4) | 36 (17.9) | 17.2 | |||||
| Sex: Male, n (%) | 201 (47.6) | 102 (46.2) | 99 (49.3) | 47.9 | 0.836 | 0.524 | 0.945 | 0.703 | 0.765 |
| Employment, n (%) | 0.001 | 0.223 | 0.713 | 0.589 | 0.845 | ||||
| In employment | 245 (58.1) | 128 (57.9) | 117 (58.2) | 62 | |||||
| Student | 36 (8.5) | 23 (10.4) | 13 (6.5) | 7 | |||||
| Not in employment | 141 (33.4) | 70 (31.7) | 68 (33.8) | 31 | |||||
| Marital status, n (%) | 0.047 | 0.013 | 0.297 | 0.705 | 0.044 | ||||
| Married/partner | 236 (55.9) | 111 (50.7) | 125 (62.2) | 52.6 | |||||
| Single | 184 (43.6) | 108 (49.3) | 76 (37.8) | 47.4 | |||||
| Education cont after minimum age, n (%) | 292 (69.2) | 174 (78.7) | 118 (58.7) | n/a | n/a | 0.001 | n/a | n/a | n/a |
| Educated to degree level, n (%) | 136 (29.9) | 90 (40.7) | 46 (22.9) | 21.6 | 0.001 | 0.032 | 0.001 | 0.001 | 0.719 |
| Health status, n (%) | n/a | 0.001 | n/a | n/a | n/a | ||||
| Good | 340 (80.6) | 163 (73.8) | 177 (88.1) | n/a | |||||
| Poor | 82 (19.4) | 58 (26.2) | 24 (12.0) | n/a | |||||
| Health satisfaction, n (%) | n/a | 0.001 | n/a | n/a | n/a | ||||
| 10 | 37 (8.8) | 15 (6.8) | 22 (11.0) | n/a | |||||
| 6–9 | 279 (66.1) | 132 (59.7) | 147 (73.1) | n/a | |||||
| 1–5 | 106 (25.1) | 74 (33.5) | 32 (15.9) | n/a | |||||
| Life satisfaction, n (%) | n/a | 0.001 | n/a | n/a | n/a | ||||
| 10 | 44 (10.4) | 15 (6.8) | 29 (14.4) | n/a | |||||
| 6–9 | 266 (63.0) | 131 (59.3) | 135 (67.2) | n/a | |||||
| 1–5 | 112 (26.5) | 75 (33.9) | 37 (18.4) | n/a | |||||
| Time taken to complete (min) | |||||||||
| Overall | |||||||||
| Mean±SD | 9.88±4.6 | 8.64±3.84 | 11.26±4.99 | n/a | n/a | 0.001 | n/a | n/a | n/a |
| Median | 8.90 | 7.35 | 10.23 | n/a | n/a | 0.001 | n/a | n/a | n/a |
| Nonexperimental questions | |||||||||
| Mean±SD | 6.12±14.88 | 4.58±2.7 | 7.81±21.28 | n/a | n/a | 0.001 | n/a | n/a | n/a |
| Median | 4.48 | 3.80 | 5.10 | n/a | n/a | 0.001 | n/a | n/a | n/a |
| Module 1 | |||||||||
| Mean±SD | 1.27±0.76 | 1.07±0.77 | 1.49±0.70 | n/a | n/a | 0.001 | n/a | n/a | n/a |
| Median | 1.05 | 0.87 | 1.35 | n/a | n/a | 0.001 | n/a | n/a | n/a |
| Module 2 | |||||||||
| Mean±SD | 1.92±1.33 | 1.80±1.63 | 2.06±0.89 | n/a | n/a | 0.045 | n/a | n/a | n/a |
| Median | 1.68 | 1.42 | 1.87 | n/a | n/a | 0.001 | n/a | n/a | n/a |
| Module 3 | |||||||||
| Mean±SD | 1.28±0.99 | 1.20±1.11 | 1.36±0.84 | n/a | n/a | 0.088 | n/a | n/a | n/a |
| Median | 1.05 | 0.92 | 1.22 | n/a | n/a | 0.001 | n/a | n/a | n/a |
Note. General population of England and Wales extracted for 18- to 65-year-olds from the 2001 census [25].
CAPI, computer-assisted personal interview; GP, general population.
Fig. 2Self-reported health status and health and life satisfaction.
Proportion of respondents choosing scenario B in different binary choice questions by using 5-min cutoff and P values using other overall and within-module cutoffs.
| Module 1 | ||||||||
| I | 67.0 | 68.2 | 0.79 | 0.77 | 0.26 | 0.23 | 0.24 | 0.25 |
| I | 54.8 | 58.7 | 0.41 | 0.36 | 0.16 | 0.45 | 0.32 | 0.24 |
| I | 81.9 | 81.6 | 0.94 | 0.23 | 0.80 | 0.71 | 0.92 | 0.97 |
| I | 98.2 | 98.5 | 0.80 | 0.30 | 0.22 | 0.13 | 0.17 | 0.11 |
| I | 91.9 | 91.5 | 0.91 | 0.63 | 0.27 | 0.71 | 0.97 | 0.56 |
| Module 2 | ||||||||
| II | 92.8 | 94.0 | 0.60 | 0.58 | 0.99 | 0.59 | 0.73 | 0.71 |
| III | 71.0 | 75.6 | 0.29 | 0.42 | 0.11 | 0.18 | 0.08 | 0.06 |
| IV | 81.9 | 83.1 | 0.75 | 0.61 | 0.81 | 0.67 | 0.73 | 0.62 |
| V | 56.6 | 60.7 | 0.39 | 0.09 | 0.68 | 0.60 | 0.72 | 0.75 |
| VI | 65.6 | 64.6 | 0.84 | 0.31 | 0.44 | 0.90 | 0.67 | 0.53 |
| Module 3 | ||||||||
| VIIa | 41.4 | 39.0 | 0.77 | 0.20 | 0.08 | 0.78 | 0.72 | 0.55 |
| VIIb | 58.0 | 60.0 | 0.78 | 0.60 | 0.93 | 0.52 | 0.71 | 0.87 |
| VIIc | 77.6 | 71.0 | 0.37 | 0.94 | 0.09 | 0.74 | 0.51 | 0.31 |
| VIId | 78.0 | 82.2 | 0.54 | 0.52 | 0.83 | 0.27 | 0.39 | 0.24 |
Note. Types I–V, scenario B equals living in full health for a shorter duration; type VI, scenario B represents immediate death; type VII, scenario B is an EQ-5D-5L health state with duration.CAPI, computer-assisted personal interview.
Group 1: Those completing the module in less than the median time taken to complete the module. Sample size: module 1: 205 (149/56); module 2: 214 (139/69); module 3, type V1: 75 (38/37); module 3, type V2: 65 (25/40).
Group 2: Those completing the module in more than or equal to the median time taken to complete the module. Sample size: module 1: 217 (72/145); module 2: 214 (82/132); module 3, type V1: 83 (20/63); module 3, type V2: 86 (25/61).
Probit regression marginal effect coefficients for the likelihood of choosing scenario B.
| Health state | 0.09 | – | – | – | – | – | – | – | – | – |
| V value | 0.05 | – | – | – | – | – | – | – | – | – |
| Duration of health state | 0.03 | – | – | – | – | – | – | – | – | – |
| Administration mode | 0.02 | 0.00 | 0.11 | 0.01 | 0.20 | 0.08 | 0.12 | 0.18 | 0.10 | 0.06 |
| Module completion time | −0.00 | 0.00 | −0.00 | −0.00 | −0.00 | 0.00 | 0.00 | 0.00 | −0.00 | −0.00 |
| Completion time×Mode interaction | 0.00 | 0.00 | −0.00 | 0.00 | −0.00 | −0.00 | −0.00 | −0.00 | 0.00 | 0.00 |
| Sex | 0.01 | 0.05 | −0.00 | 0.11 | −0.12 | 0.04 | 0.06 | −0.07 | −0.10 | 0.05 |
| Age | −0.01 | 0.00 | −0.02 | −0.00 | −0.00 | −0.00 | −0.00 | 0.00 | 0.00 | −0.00 |
| Education level | ||||||||||
| No education past minimum age | 0.03 | 0.01 | 0.04 | −0.08 | −0.00 | 0.06 | −0.05 | 0.02 | −0.04 | −0.09 |
| Educated to degree level | −0.02 | 0.00 | 0.05 | −0.04 | −0.01 | 0.03 | 0.09 | 0.16 | 0.00 | −0.06 |
| Married or with partner | −0.03 | 0.00 | −0.00 | 0.04 | −0.11 | −0.02 | −0.02 | −0.02 | 0.24 | 0.20 |
| Employment level | ||||||||||
| Employed | −0.02 | −0.02 | 0.02 | −0.00 | −0.05 | 0.06 | 0.07 | −0.07 | 0.23 | 0.10 |
| Student | −0.05 | 0.01 | 0.01 | 0.5 | −0.08 | 0.16 | 0.19 | −0.00 | 0.35 | 0.12 |
| Not working | 0.02 | 0.02 | 0.06 | 0.13 | −0.06 | −0.04 | −0.13 | −0.12 | 0.24 | 0.16 |
| Self-reported health | ||||||||||
| Health status | 0.00 | 0.01 | −0.02 | 0.04 | 0.09 | 0.12 | −0.24 | 0.07 | 0.06 | 0.01 |
| Health satisfaction | −0.04 | 0.02 | −0.01 | 0.02 | 0.06 | 0.05 | −0.09 | −0.08 | −0.12 | 0.01 |
| Life satisfaction | 0.01 | 0.05 | −0.01 | −0.07 | 0.01 | −0.02 | 0.07 | 0.10 | −0.21 | 0.07 |
| N | 2105 | 422 | 422 | 422 | 422 | 422 | 157 | 157 | 149 | 149 |
| LR χ2 | 369.94 | 9.56 | 10.62 | 21.93 | 17.73 | 15.64 | 12.08 | 15.49 | 16.19 | 11.81 |
| Pseudo | 0.17 | 0.05 | 0.02 | 0.06 | 0.03 | 0.03 | 0.05 | 0.09 | 0.08 | 0.08 |
| Log likelihood | −888.84 | −98.23 | −239.88 | −184.96 | −277.47 | −264.97 | −99.70 | −82.41 | −92.73 | −67.53 |
Note. Health state, V value, and duration can be analyzed only for type I questions.
Significant at P = 0.05.
Significant at P = 0.01.