Literature DB >> 23230569

Artificial repressors for controlling gene expression in bacteria.

Mark C Politz1, Matthew F Copeland, Brian F Pfleger.   

Abstract

Transcriptional repression is a common approach to control gene expression in synthetic biology applications. Here, an engineered DNA binding protein based upon a transcription activator-like effector (TALE) scaffold was shown to outperform LacI in blocking transcription from a promoter and to repress expression of a downstream gene in an operon.

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Year:  2012        PMID： 23230569      PMCID： PMC3749042          DOI： 10.1039/c2cc37107c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  17 in total

1.  TAL effector RVD specificities and efficiencies.

Authors:  Jana Streubel; Christina Blücher; Angelika Landgraf; Jens Boch
Journal:  Nat Biotechnol       Date:  2012-07-10       Impact factor: 54.908

2.  Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors.

Authors:  Robert Morbitzer; Patrick Römer; Jens Boch; Thomas Lahaye
Journal:  Proc Natl Acad Sci U S A       Date:  2010-11-24       Impact factor: 11.205

Review 3.  The lac repressor.

Authors:  Mitchell Lewis
Journal:  C R Biol       Date:  2005-06       Impact factor: 1.583

4.  Combinatorial engineering of intergenic regions in operons tunes expression of multiple genes.

Authors:  Brian F Pfleger; Douglas J Pitera; Christina D Smolke; Jay D Keasling
Journal:  Nat Biotechnol       Date:  2006-07-16       Impact factor: 54.908

5.  Elongation by Escherichia coli RNA polymerase is blocked in vitro by a site-specific DNA binding protein.

Authors:  P A Pavco; D A Steege
Journal:  J Biol Chem       Date:  1990-06-15       Impact factor: 5.157

6.  A simple cipher governs DNA recognition by TAL effectors.

Authors:  Matthew J Moscou; Adam J Bogdanove
Journal:  Science       Date:  2009-12-11       Impact factor: 47.728

7.  Targeted genome editing across species using ZFNs and TALENs.

Authors:  Andrew J Wood; Te-Wen Lo; Bryan Zeitler; Catherine S Pickle; Edward J Ralston; Andrew H Lee; Rainier Amora; Jeffrey C Miller; Elo Leung; Xiangdong Meng; Lei Zhang; Edward J Rebar; Philip D Gregory; Fyodor D Urnov; Barbara J Meyer
Journal:  Science       Date:  2011-06-23       Impact factor: 47.728

Review 8.  TAL effectors are remote controls for gene activation.

Authors:  Heidi Scholze; Jens Boch
Journal:  Curr Opin Microbiol       Date:  2011-01-05       Impact factor: 7.934

9.  Breaking the code of DNA binding specificity of TAL-type III effectors.

Authors:  Jens Boch; Heidi Scholze; Sebastian Schornack; Angelika Landgraf; Simone Hahn; Sabine Kay; Thomas Lahaye; Anja Nickstadt; Ulla Bonas
Journal:  Science       Date:  2009-12-11       Impact factor: 47.728

10.  Engineering synthetic TAL effectors with orthogonal target sites.

Authors:  Abhishek Garg; Jason J Lohmueller; Pamela A Silver; Thomas Z Armel
Journal:  Nucleic Acids Res       Date:  2012-05-11       Impact factor: 16.971
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  18 in total

1.  Growth-coupled bioconversion of levulinic acid to butanone.

Authors:  Christopher R Mehrer; Jacqueline M Rand; Matthew R Incha; Taylor B Cook; Benginur Demir; Ali Hussain Motagamwala; Daniel Kim; James A Dumesic; Brian F Pfleger
Journal:  Metab Eng       Date:  2019-06-19       Impact factor: 9.783

Review 2.  Application of TALEs, CRISPR/Cas and sRNAs as trans-acting regulators in prokaryotes.

Authors:  Matthew F Copeland; Mark C Politz; Brian F Pfleger
Journal:  Curr Opin Biotechnol       Date:  2014-03-12       Impact factor: 9.740

3.  Precision genetic modifications: a new era in molecular biology and crop improvement.

Authors:  Franziska Fichtner; Reynel Urrea Castellanos; Bekir Ülker
Journal:  Planta       Date:  2014-02-08       Impact factor: 4.116

4.  Principles and applications of TAL effectors for plant physiology and metabolism.

Authors:  Adam J Bogdanove
Journal:  Curr Opin Plant Biol       Date:  2014-06-05       Impact factor: 7.834

5.  Selective recognition of N4-methylcytosine in DNA by engineered transcription-activator-like effectors.

Authors:  Preeti Rathi; Sara Maurer; Daniel Summerer
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2018-06-05       Impact factor: 6.237

6.  The effect of increasing numbers of repeats on TAL effector DNA binding specificity.

Authors:  Fabio C Rinaldi; Lindsey A Doyle; Barry L Stoddard; Adam J Bogdanove
Journal:  Nucleic Acids Res       Date:  2017-06-20       Impact factor: 16.971

7.  Control of Gene Expression in Leptospira spp. by Transcription Activator-Like Effectors Demonstrates a Potential Role for LigA and LigB in Leptospira interrogans Virulence.

Authors:  Christopher J Pappas; Mathieu Picardeau
Journal:  Appl Environ Microbiol       Date:  2015-09-04       Impact factor: 4.792

8.  Genomic mining of prokaryotic repressors for orthogonal logic gates.

Authors:  Brynne C Stanton; Alec A K Nielsen; Alvin Tamsir; Kevin Clancy; Todd Peterson; Christopher A Voigt
Journal:  Nat Chem Biol       Date:  2013-12-08       Impact factor: 15.040

9.  TAL effectors and activation of predicted host targets distinguish Asian from African strains of the rice pathogen Xanthomonas oryzae pv. oryzicola while strict conservation suggests universal importance of five TAL effectors.

Authors:  Katherine E Wilkins; Nicholas J Booher; Li Wang; Adam J Bogdanove
Journal:  Front Plant Sci       Date:  2015-07-21       Impact factor: 5.753

Review 10.  Transcription activator-like effectors: a toolkit for synthetic biology.

Authors:  Richard Moore; Anita Chandrahas; Leonidas Bleris
Journal:  ACS Synth Biol       Date:  2014-02-13       Impact factor: 5.110
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