Literature DB >> 23201268

Treatment of osteoporosis in men.

J-M Kaufman1, J-Y Reginster, S Boonen, M L Brandi, C Cooper, W Dere, J-P Devogelaer, A Diez-Perez, J A Kanis, E McCloskey, B Mitlak, E Orwoll, J D Ringe, G Weryha, R Rizzoli.   

Abstract

SUMMARY: Aspects of osteoporosis in men, such as screening and identification strategies, definitions of diagnosis and intervention thresholds, and treatment options (both approved and in the pipeline) are discussed.
INTRODUCTION: Awareness of osteoporosis in men is improving, although it remains under-diagnosed and under-treated. A European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) workshop was convened to discuss osteoporosis in men and to provide a report by a panel of experts (the authors).
METHODS: A debate with an expert panel on preselected topics was conducted. RESULTS AND
CONCLUSIONS: Although additional fracture data are needed to endorse the clinical care of osteoporosis in men, consensus views were reached on diagnostic criteria and intervention thresholds. Empirical data in men display similarities with data acquired in women, despite pathophysiological differences, which may not be clinically relevant. Men should receive treatment at a similar 10-year fracture probability as in women. The design of mixed studies may reduce the lag between comparable treatments for osteoporosis in women becoming available in men.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 23201268      PMCID: PMC3662207          DOI: 10.1016/j.bone.2012.11.018

Source DB:  PubMed          Journal:  Bone        ISSN: 1873-2763            Impact factor:   4.398


  100 in total

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2.  An estimate of the worldwide prevalence and disability associated with osteoporotic fractures.

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Review 4.  Age-associated endocrine deficiencies as potential determinants of femoral neck (type II) osteoporotic fracture occurrence in elderly men.

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5.  Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis.

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6.  Epidemiology of hip fracture: Worldwide geographic variation.

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8.  Teriparatide effects on vertebral fractures and bone mineral density in men with osteoporosis: treatment and discontinuation of therapy.

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9.  Bone density and fracture risk in men.

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10.  International variations in hip fracture probabilities: implications for risk assessment.

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Review 3.  Idiopathic osteoporosis in men.

Authors:  Luigi Gennari; John P Bilezikian
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Review 7.  Various aspects of sex and gender bias in biomedical research.

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Review 8.  Osteoporosis in men: a review.

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Review 9.  Causes, consequences, and treatment of osteoporosis in men.

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