Literature DB >> 23183903

Is the optimal level of protein intake for older adults greater than the recommended dietary allowance?

Elena Volpi1, Wayne W Campbell, Johanna T Dwyer, Mary Ann Johnson, Gordon L Jensen, John E Morley, Robert R Wolfe.   

Abstract

BACKGROUND: Protein is a macronutrient essential for growth, muscle function, immunity and overall tissue homeostasis. Suboptimal protein intake can significantly impact physical function and overall health in older adults.
METHODS: This article reviews the literature on the recommendations for protein intake in older adults in light of the new evidence linking protein intake with sarcopenia and physical function. Challenges and opportunities for optimal protein nutrition in older persons are discussed.
RESULTS: Recent metabolic and epidemiological studies suggest that the current recommendations of protein intake may not be adequate for maintenance of physical function and optimal health in older adults. Methodological limitations and novel concepts in protein nutrition are also discussed.
CONCLUSION: We conclude that new research and novel research methodologies are necessary to establish the protein needs and optimal patterns of protein intake for older persons.

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Year:  2012        PMID: 23183903      PMCID: PMC3660117          DOI: 10.1093/gerona/gls229

Source DB:  PubMed          Journal:  J Gerontol A Biol Sci Med Sci        ISSN: 1079-5006            Impact factor:   6.053


  46 in total

Review 1.  Protein and amino acid requirements in the elderly.

Authors:  A V Kurpad; M Vaz
Journal:  Eur J Clin Nutr       Date:  2000-06       Impact factor: 4.016

Review 2.  Food insecurity, food and nutrition programs, and aging: experiences from Georgia.

Authors:  Jung Sun Lee; Joan G Fischer; Mary Ann Johnson
Journal:  J Nutr Elder       Date:  2010-04

3.  Physical limitations contribute to food insecurity and the food insecurity-obesity paradox in older adults at senior centers in Georgia.

Authors:  Dawn P Brewer; Christina S Catlett; Katie N Porter; Jung Sun Lee; Dorothy B Hausman; Sudha Reddy; Mary Ann Johnson
Journal:  J Nutr Elder       Date:  2010-04

4.  Protein requirement of elderly women: nitrogen balance responses to three levels of protein intake.

Authors:  M H Morse; M D Haub; W J Evans; W W Campbell
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2001-11       Impact factor: 6.053

5.  The recommended dietary allowance for protein may not be adequate for older people to maintain skeletal muscle.

Authors:  W W Campbell; T A Trappe; R R Wolfe; W J Evans
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2001-06       Impact factor: 6.053

6.  Senile anorexia in acute-ward and rehabilitations settings.

Authors:  L M Donini; C Savina; M Piredda; D Cucinotta; A Fiorito; E M Inelmen; G Sergi; L J Domiguez; M Barbagallo; C Cannella
Journal:  J Nutr Health Aging       Date:  2008-10       Impact factor: 4.075

7.  Dietary protein requirements of younger and older adults.

Authors:  Wayne W Campbell; Craig A Johnson; George P McCabe; Nadine S Carnell
Journal:  Am J Clin Nutr       Date:  2008-11       Impact factor: 7.045

Review 8.  Sarcopenic obesity: definition, cause and consequences.

Authors:  Sari Stenholm; Tamara B Harris; Taina Rantanen; Marjolein Visser; Stephen B Kritchevsky; Luigi Ferrucci
Journal:  Curr Opin Clin Nutr Metab Care       Date:  2008-11       Impact factor: 4.294

9.  Inverse regulation of protein turnover and amino acid transport in skeletal muscle of hypercatabolic patients.

Authors:  Gianni Biolo; R Y Declan Fleming; Sergio P Maggi; Thuan T Nguyen; David N Herndon; Robert R Wolfe
Journal:  J Clin Endocrinol Metab       Date:  2002-07       Impact factor: 5.958

Review 10.  Weight loss in older persons: new therapeutic approaches.

Authors:  John E Morley
Journal:  Curr Pharm Des       Date:  2007       Impact factor: 3.116

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  104 in total

Review 1.  Protein and amino acid restriction, aging and disease: from yeast to humans.

Authors:  Hamed Mirzaei; Jorge A Suarez; Valter D Longo
Journal:  Trends Endocrinol Metab       Date:  2014-08-19       Impact factor: 12.015

2.  Changes in Lean Mass and Serum Myostatin with Habitual Protein Intake and High-Velocity Resistance Training.

Authors:  A Binns; M Gray; A C Henson; I L Fort
Journal:  J Nutr Health Aging       Date:  2017       Impact factor: 4.075

3.  Development of a Novel Six-Month Nutrition Intervention for a Randomized Trial in Older Men with Mobility Limitations.

Authors:  C M Apovian; M R Singer; W W Campbell; S Bhasin; A C McCarthy; M Shah; S Basaria; L L Moore
Journal:  J Nutr Health Aging       Date:  2017       Impact factor: 4.075

Review 4.  Keeping older muscle “young” through dietary protein and physical activity.

Authors:  Daniel R Moore
Journal:  Adv Nutr       Date:  2014-09       Impact factor: 8.701

Review 5.  Nutritional supplements in support of resistance exercise to counter age-related sarcopenia.

Authors:  Stuart M Phillips
Journal:  Adv Nutr       Date:  2015-07-15       Impact factor: 8.701

6.  Hypoenergetic diet-induced reductions in myofibrillar protein synthesis are restored with resistance training and balanced daily protein ingestion in older men.

Authors:  Caoileann H Murphy; Tyler A Churchward-Venne; Cameron J Mitchell; Nathan M Kolar; Amira Kassis; Leonidas G Karagounis; Louise M Burke; John A Hawley; Stuart M Phillips
Journal:  Am J Physiol Endocrinol Metab       Date:  2015-03-03       Impact factor: 4.310

Review 7.  Frailty and nutrition: searching for evidence.

Authors:  M Bonnefoy; G Berrut; B Lesourd; M Ferry; T Gilbert; O Guérin; O Hanon; C Jeandel; E Paillaud; A Raynaud-Simon; G Ruault; Y Rolland
Journal:  J Nutr Health Aging       Date:  2015-03       Impact factor: 4.075

Review 8.  Dietary protein and exercise for preservation of lean mass and perspectives on type 2 diabetes prevention.

Authors:  Maysa Vieira de Sousa; Diana Bento da Silva Soares; Elaine Reis Caraça; Ronaldo Cardoso
Journal:  Exp Biol Med (Maywood)       Date:  2019-07-15

9.  Associations of dietary protein intake on subsequent decline in muscle mass and physical functions over four years in ambulant older Chinese people.

Authors:  R Chan; J Leung; J Woo; T Kwok
Journal:  J Nutr Health Aging       Date:  2014       Impact factor: 4.075

10.  Protein intake and exercise for optimal muscle function with aging: recommendations from the ESPEN Expert Group.

Authors:  Nicolaas E P Deutz; Jürgen M Bauer; Rocco Barazzoni; Gianni Biolo; Yves Boirie; Anja Bosy-Westphal; Tommy Cederholm; Alfonso Cruz-Jentoft; Zeljko Krznariç; K Sreekumaran Nair; Pierre Singer; Daniel Teta; Kevin Tipton; Philip C Calder
Journal:  Clin Nutr       Date:  2014-04-24       Impact factor: 7.324

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