Literature DB >> 26178029

Nutritional supplements in support of resistance exercise to counter age-related sarcopenia.

Stuart M Phillips1.   

Abstract

Age-related sarcopenia, composed of myopenia (a decline in muscle mass) and dynapenia (a decline in muscle strength), can compromise physical function, increase risk of disability, and lower quality of life in older adults. There are no available pharmaceutical treatments for this condition, but evidence shows resistance training (RT) is a viable and relatively low-cost treatment with an exceptionally positive side effect profile. Further evidence suggests that RT-induced increases in muscle mass, strength, and function can be enhanced by certain foods, nutrients, or nutritional supplements. This brief review focuses on adjunctive nutritional strategies, which have a reasonable evidence base, to enhance RT-induced gains in outcomes relevant to sarcopenia and to reducing risk of functional declines.
© 2015 American Society for Nutrition.

Entities:  

Keywords:  Leu; aging; creatine; dynapenia; function; protein; vitamin D; β-HMB

Mesh:

Substances:

Year:  2015        PMID: 26178029      PMCID: PMC4496741          DOI: 10.3945/an.115.008367

Source DB:  PubMed          Journal:  Adv Nutr        ISSN: 2161-8313            Impact factor:   8.701


  97 in total

Review 1.  Bigger weights may not beget bigger muscles: evidence from acute muscle protein synthetic responses after resistance exercise.

Authors:  Nicholas A Burd; Cameron J Mitchell; Tyler A Churchward-Venne; Stuart M Phillips
Journal:  Appl Physiol Nutr Metab       Date:  2012-04-26       Impact factor: 2.665

2.  Dietary protein intake is associated with lean body mass in community-dwelling older adults.

Authors:  Olof G Geirsdottir; Atli Arnarson; Alfons Ramel; Palmi V Jonsson; Inga Thorsdottir
Journal:  Nutr Res       Date:  2013-06-27       Impact factor: 3.315

Review 3.  Optimal protein intake in the elderly.

Authors:  Robert R Wolfe; Sharon L Miller; Kevin B Miller
Journal:  Clin Nutr       Date:  2008-09-25       Impact factor: 7.324

4.  Muscle mass index as a predictor of longevity in older adults.

Authors:  Preethi Srikanthan; Arun S Karlamangla
Journal:  Am J Med       Date:  2014-02-18       Impact factor: 4.965

5.  Creatine supplementation improves muscular performance in older men.

Authors:  Lincoln A Gotshalk; Jeff S Volek; Robert S Staron; Craig R Denegar; Fredrick C Hagerman; William J Kraemer
Journal:  Med Sci Sports Exerc       Date:  2002-03       Impact factor: 5.411

6.  Supplementation of a suboptimal protein dose with leucine or essential amino acids: effects on myofibrillar protein synthesis at rest and following resistance exercise in men.

Authors:  Tyler A Churchward-Venne; Nicholas A Burd; Cameron J Mitchell; Daniel W D West; Andrew Philp; George R Marcotte; Steven K Baker; Keith Baar; Stuart M Phillips
Journal:  J Physiol       Date:  2012-03-25       Impact factor: 5.182

7.  Leucine stimulates translation initiation in skeletal muscle of postabsorptive rats via a rapamycin-sensitive pathway.

Authors:  J C Anthony; F Yoshizawa; T G Anthony; T C Vary; L S Jefferson; S R Kimball
Journal:  J Nutr       Date:  2000-10       Impact factor: 4.798

8.  Elderly men and women benefit equally from prolonged resistance-type exercise training.

Authors:  Marika Leenders; Lex B Verdijk; Letty van der Hoeven; Janneau van Kranenburg; Rachel Nilwik; Luc J C van Loon
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2012-12-07       Impact factor: 6.053

Review 9.  Creatine supplementation and aging musculoskeletal health.

Authors:  Darren G Candow; Philip D Chilibeck; Scott C Forbes
Journal:  Endocrine       Date:  2013-11-05       Impact factor: 3.633

10.  Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults.

Authors:  Elena Volpi; Hisamine Kobayashi; Melinda Sheffield-Moore; Bettina Mittendorfer; Robert R Wolfe
Journal:  Am J Clin Nutr       Date:  2003-08       Impact factor: 7.045

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  40 in total

Review 1.  Resistance Training and Skeletal Muscle Protein Metabolism in Eumenorrheic Females: Implications for Researchers and Practitioners.

Authors:  Olivia E Knowles; Brad Aisbett; Luana C Main; Eric J Drinkwater; Liliana Orellana; Séverine Lamon
Journal:  Sports Med       Date:  2019-11       Impact factor: 11.136

2.  Prevalence and Diagnosis of Sarcopenia in Residential Facilities: A Systematic Review.

Authors:  Ana Isabel Rodríguez-Rejón; María Dolores Ruiz-López; Carmina Wanden-Berghe; Reyes Artacho
Journal:  Adv Nutr       Date:  2019-01-01       Impact factor: 8.701

Review 3.  Role of Inactivity in Chronic Diseases: Evolutionary Insight and Pathophysiological Mechanisms.

Authors:  Frank W Booth; Christian K Roberts; John P Thyfault; Gregory N Ruegsegger; Ryan G Toedebusch
Journal:  Physiol Rev       Date:  2017-10-01       Impact factor: 37.312

Review 4.  Pharmacological targeting of age-related changes in skeletal muscle tissue.

Authors:  Aurel B Leuchtmann; Christoph Handschin
Journal:  Pharmacol Res       Date:  2019-03-04       Impact factor: 7.658

Review 5.  Publication trends in cachexia and sarcopenia in elderly heart failure patients.

Authors:  Jochen Springer; Stefan D Anker
Journal:  Wien Klin Wochenschr       Date:  2016-11-24       Impact factor: 1.704

6.  Predictive Value of Preoperative Sarcopenia in Patients with Gastric Cancer: a Meta-analysis and Systematic Review.

Authors:  Zhengdao Yang; Xin Zhou; Bin Ma; Yanan Xing; Xue Jiang; Zhenning Wang
Journal:  J Gastrointest Surg       Date:  2018-07-09       Impact factor: 3.452

Review 7.  Perspective: Protein Requirements and Optimal Intakes in Aging: Are We Ready to Recommend More Than the Recommended Daily Allowance?

Authors:  Daniel A Traylor; Stefan H M Gorissen; Stuart M Phillips
Journal:  Adv Nutr       Date:  2018-05-01       Impact factor: 8.701

8.  Impact of sarcopenia on outcomes of locally advanced esophageal cancer patients treated with neoadjuvant chemoradiation followed by surgery.

Authors:  Gilbert Z Murimwa; Puja S Venkat; William Jin; Susan Leuthold; Kujtim Latifi; Khaldoun Almhanna; Jose M Pimiento; Jacques-Pierre Fontaine; Sarah E Hoffe; Jessica M Frakes
Journal:  J Gastrointest Oncol       Date:  2017-10

9.  Vitamin D supplementation does not enhance resistance training-induced gains in muscle strength and lean body mass in vitamin D deficient young men.

Authors:  Lauri Savolainen; Saima Timpmann; Martin Mooses; Evelin Mäestu; Luule Medijainen; Lisette Tõnutare; Frederik Ross; Märt Lellsaar; Eve Unt; Vahur Ööpik
Journal:  Eur J Appl Physiol       Date:  2021-04-05       Impact factor: 3.078

10.  Presarcopenia and its Impact on Disability in Female Patients With Rheumatoid Arthritis.

Authors:  Meltem Alkan Melikoğlu
Journal:  Arch Rheumatol       Date:  2017-01-18       Impact factor: 1.472

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