Literature DB >> 24814383

Protein intake and exercise for optimal muscle function with aging: recommendations from the ESPEN Expert Group.

Nicolaas E P Deutz1, Jürgen M Bauer2, Rocco Barazzoni3, Gianni Biolo3, Yves Boirie4, Anja Bosy-Westphal5, Tommy Cederholm6, Alfonso Cruz-Jentoft7, Zeljko Krznariç8, K Sreekumaran Nair9, Pierre Singer10, Daniel Teta11, Kevin Tipton12, Philip C Calder13.   

Abstract

The aging process is associated with gradual and progressive loss of muscle mass along with lowered strength and physical endurance. This condition, sarcopenia, has been widely observed with aging in sedentary adults. Regular aerobic and resistance exercise programs have been shown to counteract most aspects of sarcopenia. In addition, good nutrition, especially adequate protein and energy intake, can help limit and treat age-related declines in muscle mass, strength, and functional abilities. Protein nutrition in combination with exercise is considered optimal for maintaining muscle function. With the goal of providing recommendations for health care professionals to help older adults sustain muscle strength and function into older age, the European Society for Clinical Nutrition and Metabolism (ESPEN) hosted a Workshop on Protein Requirements in the Elderly, held in Dubrovnik on November 24 and 25, 2013. Based on the evidence presented and discussed, the following recommendations are made (a) for healthy older people, the diet should provide at least 1.0-1.2 g protein/kg body weight/day, (b) for older people who are malnourished or at risk of malnutrition because they have acute or chronic illness, the diet should provide 1.2-1.5 g protein/kg body weight/day, with even higher intake for individuals with severe illness or injury, and (c) daily physical activity or exercise (resistance training, aerobic exercise) should be undertaken by all older people, for as long as possible.
Copyright © 2014 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

Entities:  

Keywords:  Aging; Amino acids; Exercise; Nutrition; Protein; Sarcopenic obesity

Mesh:

Substances:

Year:  2014        PMID: 24814383      PMCID: PMC4208946          DOI: 10.1016/j.clnu.2014.04.007

Source DB:  PubMed          Journal:  Clin Nutr        ISSN: 0261-5614            Impact factor:   7.324


  87 in total

1.  Protein supplementation increases muscle mass gain during prolonged resistance-type exercise training in frail elderly people: a randomized, double-blind, placebo-controlled trial.

Authors:  Michael Tieland; Marlou L Dirks; Nikita van der Zwaluw; Lex B Verdijk; Ondine van de Rest; Lisette C P G M de Groot; Luc J C van Loon
Journal:  J Am Med Dir Assoc       Date:  2012-07-06       Impact factor: 4.669

2.  Resistance exercise enhances myofibrillar protein synthesis with graded intakes of whey protein in older men.

Authors:  Yifan Yang; Leigh Breen; Nicholas A Burd; Amy J Hector; Tyler A Churchward-Venne; Andrea R Josse; M A Tarnopolsky; Stuart M Phillips
Journal:  Br J Nutr       Date:  2012-02-07       Impact factor: 3.718

3.  Long-term leucine supplementation does not increase muscle mass or strength in healthy elderly men.

Authors:  Suzanne Verhoeven; Kristof Vanschoonbeek; Lex B Verdijk; René Koopman; Will K W H Wodzig; Paul Dendale; Luc J C van Loon
Journal:  Am J Clin Nutr       Date:  2009-03-25       Impact factor: 7.045

Review 4.  Impaired protein metabolism: interlinks between obesity, insulin resistance and inflammation.

Authors:  C Guillet; A Masgrau; S Walrand; Y Boirie
Journal:  Obes Rev       Date:  2012-12       Impact factor: 9.213

Review 5.  Elderly persons with ICU-acquired weakness: the potential role for β-hydroxy-β-methylbutyrate (HMB) supplementation?

Authors:  Adam Rahman; Kenneth Wilund; Peter J Fitschen; Khursheed Jeejeebhoy; Ravi Agarwala; John W Drover; Marina Mourtzakis
Journal:  JPEN J Parenter Enteral Nutr       Date:  2013-09-26       Impact factor: 4.016

6.  Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion.

Authors:  Elisa I Glover; Stuart M Phillips; Bryan R Oates; Jason E Tang; Mark A Tarnopolsky; Anna Selby; Kenneth Smith; Michael J Rennie
Journal:  J Physiol       Date:  2008-10-27       Impact factor: 5.182

Review 7.  Sarcopenic obesity: definition, cause and consequences.

Authors:  Sari Stenholm; Tamara B Harris; Taina Rantanen; Marjolein Visser; Stephen B Kritchevsky; Luigi Ferrucci
Journal:  Curr Opin Clin Nutr Metab Care       Date:  2008-11       Impact factor: 4.294

8.  Are elderly hospitalized patients getting enough protein?

Authors:  Cathy Gaillard; Emmanuel Alix; Yves Boirie; Gilles Berrut; Patrick Ritz
Journal:  J Am Geriatr Soc       Date:  2008-06       Impact factor: 5.562

Review 9.  Aging and chronic kidney disease.

Authors:  Kosaku Nitta; Kazuyoshi Okada; Mitsuru Yanai; Susumu Takahashi
Journal:  Kidney Blood Press Res       Date:  2014-03-03       Impact factor: 2.687

10.  Endurance exercise as a countermeasure for aging.

Authors:  Ian R Lanza; Daniel K Short; Kevin R Short; Sreekumar Raghavakaimal; Rita Basu; Michael J Joyner; Joseph P McConnell; K Sreekumaran Nair
Journal:  Diabetes       Date:  2008-08-20       Impact factor: 9.461

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  313 in total

1.  Does supplementation with leucine-enriched protein alone and in combination with fish-oil-derived n-3 PUFA affect muscle mass, strength, physical performance, and muscle protein synthesis in well-nourished older adults? A randomized, double-blind, placebo-controlled trial.

Authors:  Caoileann H Murphy; Ellen M Flanagan; Giuseppe De Vito; Davide Susta; Kathleen A J Mitchelson; Elena de Marco Castro; Joan M G Senden; Joy P B Goessens; Agnieszka Mikłosz; Adrian Chabowski; Ricardo Segurado; Clare A Corish; Sinead N McCarthy; Brendan Egan; Luc J C van Loon; Helen M Roche
Journal:  Am J Clin Nutr       Date:  2021-06-01       Impact factor: 7.045

2.  Nutrient Intake During Diet-Induced Weight Loss and Exercise Interventions in a Randomized Trial in Older Overweight and Obese Adults.

Authors:  G D Miller; D P Beavers; D Hamm; S L Mihalko; S P Messier
Journal:  J Nutr Health Aging       Date:  2017       Impact factor: 4.075

Review 3.  Fall and Fracture Risk in Sarcopenia and Dynapenia With and Without Obesity: the Role of Lifestyle Interventions.

Authors:  David Scott; Robin M Daly; Kerrie M Sanders; Peter R Ebeling
Journal:  Curr Osteoporos Rep       Date:  2015-08       Impact factor: 5.096

Review 4.  Osteosarcopenia: where bone, muscle, and fat collide.

Authors:  H P Hirschfeld; R Kinsella; G Duque
Journal:  Osteoporos Int       Date:  2017-07-22       Impact factor: 4.507

5.  Slimming down in old age.

Authors:  Gordon I Smith; Bettina Mittendorfer
Journal:  Am J Clin Nutr       Date:  2014-12-24       Impact factor: 7.045

6.  Hypoenergetic diet-induced reductions in myofibrillar protein synthesis are restored with resistance training and balanced daily protein ingestion in older men.

Authors:  Caoileann H Murphy; Tyler A Churchward-Venne; Cameron J Mitchell; Nathan M Kolar; Amira Kassis; Leonidas G Karagounis; Louise M Burke; John A Hawley; Stuart M Phillips
Journal:  Am J Physiol Endocrinol Metab       Date:  2015-03-03       Impact factor: 4.310

7.  Effect of Protein Supplementation Combined with Resistance Training on Muscle Mass, Strength and Function in the Elderly: A Systematic Review and Meta-Analysis.

Authors:  L Hou; Y Lei; X Li; C Huo; X Jia; J Yang; R Xu; X Wang
Journal:  J Nutr Health Aging       Date:  2019       Impact factor: 4.075

Review 8.  Muscle wasting in heart failure : The role of nutrition.

Authors:  Masakazu Saitoh; Marcelo Rodrigues Dos Santos; Stephan von Haehling
Journal:  Wien Klin Wochenschr       Date:  2016-10-19       Impact factor: 1.704

9.  Diet Modeling in Older Americans: The Impact of Increasing Plant-Based Foods or Dairy Products on Protein Intake.

Authors:  J A Houchins; C J Cifelli; E Demmer; V L Fulgoni
Journal:  J Nutr Health Aging       Date:  2017       Impact factor: 4.075

Review 10.  Dizziness and Unstable Gait in Old Age: Etiology, Diagnosis and Treatment.

Authors:  Klaus Jahn; Reto W Kressig; Stephanie A Bridenbaugh; Thomas Brandt; Roman Schniepp
Journal:  Dtsch Arztebl Int       Date:  2015-06-05       Impact factor: 5.594

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