Literature DB >> 23154872

Protein surface and core dynamics show concerted hydration-dependent activation.

Kathleen Wood1, François-Xavier Gallat, Renee Otten, Auke J van Heel, Mathilde Lethier, Lambert van Eijck, Martine Moulin, Michael Haertlein, Martin Weik, Frans A A Mulder.   

Abstract

By specifically labeling leucine/valine methyl groups and lysine side chains "inside" and "outside" dynamics of proteins on the nanosecond timescale are compared using neutron scattering. Surprisingly, both groups display similar dynamics as a function of temperature, and the buried hydrophobic core is sensitive to hydration and undergoes a dynamical transition.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2012        PMID： 23154872     DOI： 10.1002/anie.201205898

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  13 in total

1.  The unusual internal motion of the villin headpiece subdomain.

Authors:  Kyle W Harpole; Evan S O'Brien; Matthew A Clark; C James McKnight; Liliya Vugmeyster; A Joshua Wand
Journal:  Protein Sci       Date:  2015-10-29       Impact factor: 6.725

2.  Zaccai neutron resilience and site-specific hydration dynamics in a globular protein.

Authors:  Yinglong Miao; Liang Hong; Zheng Yi; Jeremy C Smith
Journal:  Eur Phys J E Soft Matter       Date:  2013-07-16       Impact factor: 1.890

3.  Effect of subdomain interactions on methyl group dynamics in the hydrophobic core of villin headpiece protein.

Authors:  Liliya Vugmeyster; Tien Do; Dmitry Ostrovsky; Riqianq Fu
Journal:  Protein Sci       Date:  2013-12-03       Impact factor: 6.725

4.  Fast Motions of Key Methyl Groups in Amyloid-β Fibrils.

Authors:  Liliya Vugmeyster; Dmitry Ostrovsky; Matthew A Clark; Isaac B Falconer; Gina L Hoatson; Wei Qiang
Journal:  Biophys J       Date:  2016-11-15       Impact factor: 4.033

Review 5.  Static solid-state 2H NMR methods in studies of protein side-chain dynamics.

Authors:  Liliya Vugmeyster; Dmitry Ostrovsky
Journal:  Prog Nucl Magn Reson Spectrosc       Date:  2017-03-14       Impact factor: 9.795

6.  Aromatic Ring Dynamics, Thermal Activation, and Transient Conformations of a 468 kDa Enzyme by Specific 1H-13C Labeling and Fast Magic-Angle Spinning NMR.

Authors:  Diego F Gauto; Pavel Macek; Alessandro Barducci; Hugo Fraga; Audrey Hessel; Tsutomu Terauchi; David Gajan; Yohei Miyanoiri; Jerome Boisbouvier; Roman Lichtenecker; Masatsune Kainosho; Paul Schanda
Journal:  J Am Chem Soc       Date:  2019-07-05       Impact factor: 15.419

7.  Solvent-Driven Dynamical Crossover in the Phenylalanine Side-Chain from the Hydrophobic Core of Amyloid Fibrils Detected by 2H NMR Relaxation.

Authors:  Liliya Vugmeyster; Dmitry Ostrovsky; Gina L Hoatson; Wei Qiang; Isaac B Falconer
Journal:  J Phys Chem B       Date:  2017-07-21       Impact factor: 2.991

8.  Solid state deuterium NMR study of LKα14 peptide aggregation in biosilica.

Authors:  Helen E Ferreira; Gary P Drobny
Journal:  Biointerphases       Date:  2017-06-27       Impact factor: 2.456

9.  Dynamics of Hydrophobic Core Phenylalanine Residues Probed by Solid-State Deuteron NMR.

Authors:  Liliya Vugmeyster; Dmitry Ostrovsky; Toni Villafranca; Janelle Sharp; Wei Xu; Andrew S Lipton; Gina L Hoatson; Robert L Vold
Journal:  J Phys Chem B       Date:  2015-11-12       Impact factor: 2.991

10.  Dynamics from elastic neutron-scattering via direct measurement of the running time-integral of the van Hove distribution function.

Authors:  Antonio Benedetto; Gordon J Kearley
Journal:  Sci Rep       Date:  2019-08-02       Impact factor: 4.379
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