Literature DB >> 23143149

One-pot synthesis of 2-phenylimidazo[1,2-α]pyridines from acetophenone, [Bmim]Br(3) and 2-aminopyridine under solvent-free conditions.

Zhang-Gao Le1, Zong-Bo Xie, Jian-Ping Xu.   

Abstract

One-pot synthesis of 2-phenylimidazo[1,2-α]pyridines from acetophenone, [Bmim]Br(3) and 2-aminopyridine under solvent-free conditions in the presence of Na(2)CO(3), gave the corresponding 2-phenylimidazo[1,2-α]pyridines in excellent yields ranging from 72% to 89%.

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Year:  2012        PMID： 23143149      PMCID： PMC6269035          DOI： 10.3390/molecules171113368

Source DB:  PubMed          Journal:  Molecules        ISSN： 1420-3049            Impact factor:   4.411


  17 in total

1.  Imidazo[1,2-a]pyridines susceptible to excited state intramolecular proton transfer: one-pot synthesis via an Ortoleva-King reaction.

Authors:  Anton J Stasyuk; Marzena Banasiewicz; Michał K Cyrański; Daniel T Gryko
Journal:  J Org Chem       Date:  2012-06-11       Impact factor: 4.354

2.  Synthesis and SAR studies of very potent imidazopyridine antiprotozoal agents.

Authors:  Tesfaye Biftu; Dennis Feng; Michael Fisher; Gui-Bai Liang; Xiaoxia Qian; Andrew Scribner; Richard Dennis; Shuliang Lee; Paul A Liberator; Chris Brown; Anne Gurnett; Penny S Leavitt; Donald Thompson; John Mathew; Andrew Misura; Samantha Samaras; Tamas Tamas; Joseph F Sina; Kathleen A McNulty; Crystal G McKnight; Dennis M Schmatz; Matthew Wyvratt
Journal:  Bioorg Med Chem Lett       Date:  2006-02-07       Impact factor: 2.823

3.  Efficient syntheses of imidazolo[1,2-a]pyridines and -[2, 1-a]isoquinolines.

Authors:  A R Katritzky; G Qiu; Q H Long; H Y He; P J Steel
Journal:  J Org Chem       Date:  2000-12-29       Impact factor: 4.354

4.  Antiviral 2,5-disubstituted imidazo[4,5-c]pyridines: from anti-pestivirus to anti-hepatitis C virus activity.

Authors:  Gerhard Puerstinger; Jan Paeshuyse; Erik De Clercq; Johan Neyts
Journal:  Bioorg Med Chem Lett       Date:  2006-10-19       Impact factor: 2.823

5.  Research on heterocyclic compounds, Part 40. 2-Phenylimidazo[1,2-a]pyridine-3-carboxylic acid derivatives: synthesis and antiinflammatory activity.

Authors:  A Di Chiacchio; M G Rimoli; L Avallone; F Arena; E Abignente; W Filippelli; A Filippelli; G Falcone
Journal:  Arch Pharm (Weinheim)       Date:  1998-09       Impact factor: 3.751

6.  Synthesis and antiprotozoal activity of novel bis-benzamidino imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines.

Authors:  Mohamed A Ismail; Reem K Arafa; Tanja Wenzler; Reto Brun; Farial A Tanious; W David Wilson; David W Boykin
Journal:  Bioorg Med Chem       Date:  2007-10-18       Impact factor: 3.641

7.  Antiulcer agents. 4. Conformational considerations and the antiulcer activity of substituted imidazo[1,2-a]pyridines and related analogues.

Authors:  J J Kaminski; C Puchalski; D M Solomon; R K Rizvi; D J Conn; A J Elliott; R G Lovey; H Guzik; P J Chiu; J F Long
Journal:  J Med Chem       Date:  1989-08       Impact factor: 7.446

8.  Imidazopyrimidines, potent inhibitors of p38 MAP kinase.

Authors:  Kenneth C Rupert; James R Henry; John H Dodd; Scott A Wadsworth; Druie E Cavender; Gilbert C Olini; Bohumila Fahmy; John J Siekierka
Journal:  Bioorg Med Chem Lett       Date:  2003-02-10       Impact factor: 2.823

9.  Imidazo[1,2-a]pyrimidines and imidazo[1,2-a]pyrazines: the role of nitrogen position in inotropic activity.

Authors:  W A Spitzer; F Victor; G D Pollock; J S Hayes
Journal:  J Med Chem       Date:  1988-08       Impact factor: 7.446

10.  Fully automated continuous flow synthesis of highly functionalized imidazo[1,2-a] heterocycles.

Authors:  Ananda Herath; Russell Dahl; Nicholas D P Cosford
Journal:  Org Lett       Date:  2010-02-05       Impact factor: 6.005
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  1 in total

1.  Iodine Promoted Efficient Synthesis of 2-Arylimidazo[1,2-a]pyridines in Aqueous Media: A Comparative Study between Micellar Catalysis and an "On-Water" Platform.

Authors:  Zigmee T Bhutia; Padmini C Panjikar; Shruti Iyer; Amrita Chatterjee; Mainak Banerjee
Journal:  ACS Omega       Date:  2020-05-26
  1 in total

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