Literature DB >> 23105670

Effect ofVitex negundo leaf extract on the free radicals scavengers in complete Freund's adjuvant induced arthritic rats.

P Renuka Devi1, S Krishna Kumari, C Kokilavani.   

Abstract

The effect of the oral administration ofVitex negundo leaf extract on the levels of enzymic and non-enzymic antioxidants were studied in the adjuvant induced arthritic (AIA) rats The levels of antioxidant enzymes such as SOD, CAT, GPx, G6PD, GSH and Vit-C were estimated in various groups of the experimental rats. It was observed that the antioxidant enzyme levels in the AIA were significantly low when compared to normal rats. A significant decrease in enzymic antioxidant-SOD, CAT, GPx, G6PD and non-enzymic antioxidant-GSH, Vit-C were observed in the liver of AIA rats compared to the normal rats. These results suggest that the leaf extract ofVitex negundo possesses antioxidant activity.

Entities:  

Keywords:  Antioxidant; Free radicals; Vitex negundo

Year:  2007        PMID: 23105670      PMCID: PMC3454276          DOI: 10.1007/BF02912899

Source DB:  PubMed          Journal:  Indian J Clin Biochem        ISSN: 0970-1915


  24 in total

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Journal:  Science       Date:  1983-04-29       Impact factor: 47.728

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  4 in total

1.  Antiestrogenic and Anti-Inflammatory Potential of n-Hexane Fraction of Vitex negundo Linn Leaf Extract: A Probable Mechanism for Blastocyst Implantation Failure in Mus musculus.

Authors:  Mehul Jivrajani; Nirav Ravat; Sheetal Anandjiwala; Manish Nivsarkar
Journal:  Int Sch Res Notices       Date:  2014-10-29

2.  Green synthesis of gold nanoparticles from Manilkara zapota L. extract and the evaluation of its intrinsic in vivo antiarthritic potential.

Authors:  Mahnoor Ijaz; Maryam Fatima; Rukhsana Anwar; Maliha Uroos
Journal:  RSC Adv       Date:  2021-08-09       Impact factor: 4.036

3.  Vitex negundo inhibits cyclooxygenase-2 inflammatory cytokine-mediated inflammation on carrageenan-induced rat hind paw edema.

Authors:  Pronobesh Chattopadhyay; Soilyadhar Hazarika; Sunil Dhiman; Aadesh Upadhyay; Anurag Pandey; Sanjeev Karmakar; Lokendra Singh
Journal:  Pharmacognosy Res       Date:  2012-07

4.  Anti-nephrotoxic activity of some medicinal plants from tribal rich pockets of Odisha.

Authors:  Satyaranjan Mishra; Saumya Ranjan Pani; Sabuj Sahoo
Journal:  Pharmacognosy Res       Date:  2014-07
  4 in total

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