Literature DB >> 7230155

Free-radical oxidation (peroxidation) products in serum and synovial fluid in rheumatoid arthritis.

J Lunec, S P Halloran, A G White, T L Dormandy.   

Abstract

Free-radical oxidation (peroxidation) products were measured in (a) 65 synovial effusions and (b) 30 sera from normal subjects and 58 sera from patients with rheumatoid arthritis (RA). Free-radical oxidation products were detectable in 90% of synovial fluids, their concentration being higher in "inflammatory" than in "degenerative" joint disease. Free-radical oxidation products in serum were significantly elevated in patients with RA compared to normal controls; the levels declined after treatment with a variety of antiinflammatory agents.

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Year:  1981        PMID： 7230155

Source DB:  PubMed          Journal:  J Rheumatol        ISSN： 0315-162X            Impact factor:   4.666


  53 in total

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