Literature DB >> 23103879

Phase-gradient microscopy in thick tissue with oblique back-illumination.

Tim N Ford1, Kengyeh K Chu, Jerome Mertz.   

Abstract

Phase-contrast techniques, such as differential interference contrast microscopy, are widely used to obtain morphological images of unstained biological samples. The transillumination geometry required for these techniques restricts their application to thin samples. We introduce oblique back-illumination microscopy, a method of collecting en face phase-gradient images of thick scattering samples, enabling near-video-rate in vivo phase imaging with a miniaturized probe suitable for endoscopy.

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Year:  2012        PMID： 23103879     DOI： 10.1038/nmeth.2219

Source DB:  PubMed          Journal:  Nat Methods        ISSN： 1548-7091            Impact factor:   28.547


  8 in total

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  8 in total
  37 in total

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2.  Video-rate imaging of microcirculation with single-exposure oblique back-illumination microscopy.

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Journal:  J Biomed Opt       Date:  2013-06       Impact factor: 3.170

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