Literature DB >> 23055396

2'-Fluoro RNA shows increased Watson-Crick H-bonding strength and stacking relative to RNA: evidence from NMR and thermodynamic data.

Amritraj Patra1, Michael Paolillo, Klaus Charisse, Muthiah Manoharan, Eriks Rozners, Martin Egli.   

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Year:  2012        PMID： 23055396      PMCID： PMC3757553          DOI： 10.1002/anie.201204946

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  28 in total

1.  N1...N3 hydrogen bonds of A:U base pairs of RNA are stronger than those of A:T base pairs of DNA.

Authors:  Ioannis Vakonakis; Andy C LiWang
Journal:  J Am Chem Soc       Date:  2004-05-12       Impact factor: 15.419

2.  Synthesis and antisense properties of fluoro cyclohexenyl nucleic acid (F-CeNA), a nuclease stable mimic of 2'-fluoro RNA.

Authors:  Punit P Seth; Jinghua Yu; Ali Jazayeri; Pradeep S Pallan; Charles R Allerson; Michael E Østergaard; Fengwu Liu; Piet Herdewijn; Martin Egli; Eric E Swayze
Journal:  J Org Chem       Date:  2012-05-18       Impact factor: 4.354

3.  1JNH values show that N1...N3 hydrogen bonds are stronger in dsRNA A:U than dsDNA A:T base pairs.

Authors:  Marlon N Manalo; Xiangming Kong; Andy LiWang
Journal:  J Am Chem Soc       Date:  2005-12-28       Impact factor: 15.419

4.  Fully 2'-modified oligonucleotide duplexes with improved in vitro potency and stability compared to unmodified small interfering RNA.

Authors:  Charles R Allerson; Namir Sioufi; Russell Jarres; Thazha P Prakash; Nishant Naik; Andres Berdeja; Lisa Wanders; Richard H Griffey; Eric E Swayze; Balkrishen Bhat
Journal:  J Med Chem       Date:  2005-02-24       Impact factor: 7.446

5.  Thermodynamic characterization of naturally occurring RNA tetraloops.

Authors:  Justin P Sheehy; Amber R Davis; Brent M Znosko
Journal:  RNA       Date:  2010-01-04       Impact factor: 4.942

6.  Unique gene-silencing and structural properties of 2'-fluoro-modified siRNAs.

Authors:  Muthiah Manoharan; Akin Akinc; Rajendra K Pandey; June Qin; Philipp Hadwiger; Matthias John; Kathy Mills; Klaus Charisse; Martin A Maier; Lubomir Nechev; Emily M Greene; Pradeep S Pallan; Eriks Rozners; Kallanthottathil G Rajeev; Martin Egli
Journal:  Angew Chem Int Ed Engl       Date:  2011-01-31       Impact factor: 15.336

7.  RNA hydration: a detailed look.

Authors:  M Egli; S Portmann; N Usman
Journal:  Biochemistry       Date:  1996-07-02       Impact factor: 3.162

8.  Structure and thermodynamics of a conserved U2 snRNA domain from yeast and human.

Authors:  Dipali G Sashital; Vincenzo Venditti; Cortney G Angers; Gabriel Cornilescu; Samuel E Butcher
Journal:  RNA       Date:  2007-01-22       Impact factor: 4.942

9.  Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets.

Authors:  A M Kawasaki; M D Casper; S M Freier; E A Lesnik; M C Zounes; L L Cummins; C Gonzalez; P D Cook
Journal:  J Med Chem       Date:  1993-04-02       Impact factor: 7.446

Review 10.  Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease.

Authors:  Eugene W M Ng; David T Shima; Perry Calias; Emmett T Cunningham; David R Guyer; Anthony P Adamis
Journal:  Nat Rev Drug Discov       Date:  2006-02       Impact factor: 84.694
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  21 in total

1.  Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing.

Authors:  Hao Yin; Chun-Qing Song; Sneha Suresh; Qiongqiong Wu; Stephen Walsh; Luke Hyunsik Rhym; Esther Mintzer; Mehmet Fatih Bolukbasi; Lihua Julie Zhu; Kevin Kauffman; Haiwei Mou; Alicia Oberholzer; Junmei Ding; Suet-Yan Kwan; Roman L Bogorad; Timofei Zatsepin; Victor Koteliansky; Scot A Wolfe; Wen Xue; Robert Langer; Daniel G Anderson
Journal:  Nat Biotechnol       Date:  2017-11-13       Impact factor: 54.908

2.  RNA Nanoparticles as Rubber for Compelling Vessel Extravasation to Enhance Tumor Targeting and for Fast Renal Excretion to Reduce Toxicity.

Authors:  Chiran Ghimire; Hongzhi Wang; Hui Li; Mario Vieweger; Congcong Xu; Peixuan Guo
Journal:  ACS Nano       Date:  2020-09-16       Impact factor: 15.881

Review 3.  The dynamic, motile and deformative properties of RNA nanoparticles facilitate the third milestone of drug development.

Authors:  Xin Li; Abhjeet S Bhullar; Daniel W Binzel; Peixuan Guo
Journal:  Adv Drug Deliv Rev       Date:  2022-05-05       Impact factor: 17.873

4.  Synthesis, duplex stabilization and structural properties of a fluorinated carbocyclic LNA analogue.

Authors:  Punit P Seth; Pradeep S Pallan; Eric E Swayze; Martin Egli
Journal:  Chembiochem       Date:  2012-11-28       Impact factor: 3.164

5.  A purification method for a molecular complex in which a scaffold molecule is fully loaded with heterogeneous molecules.

Authors:  Shoji J Ohuchi; Fumihiko Sagawa; Hirohisa Ohno; Tan Inoue
Journal:  PLoS One       Date:  2015-03-17       Impact factor: 3.240

6.  Surprising base pairing and structural properties of 2'-trifluoromethylthio-modified ribonucleic acids.

Authors:  Marija Košutić; Lukas Jud; Cyrielle Da Veiga; Marina Frener; Katja Fauster; Christoph Kreutz; Eric Ennifar; Ronald Micura
Journal:  J Am Chem Soc       Date:  2014-04-25       Impact factor: 15.419

7.  Stabilization of i-motif structures by 2'-β-fluorination of DNA.

Authors:  Hala Abou Assi; Robert W Harkness; Nerea Martin-Pintado; Christopher J Wilds; Ramón Campos-Olivas; Anthony K Mittermaier; Carlos González; Masad J Damha
Journal:  Nucleic Acids Res       Date:  2016-05-10       Impact factor: 16.971

8.  2'-O-Trifluoromethylated RNA - a powerful modification for RNA chemistry and NMR spectroscopy.

Authors:  Maximilian Himmelstoß; Kevin Erharter; Eva Renard; Eric Ennifar; Christoph Kreutz; Ronald Micura
Journal:  Chem Sci       Date:  2020-09-24       Impact factor: 9.825

Review 9.  From Antisense RNA to RNA Modification: Therapeutic Potential of RNA-Based Technologies.

Authors:  Hironori Adachi; Martin Hengesbach; Yi-Tao Yu; Pedro Morais
Journal:  Biomedicines       Date:  2021-05-14

10.  Synthesis of N3'-P5'-linked phosphoramidate DNA by nonenzymatic template-directed primer extension.

Authors:  Shenglong Zhang; Na Zhang; J Craig Blain; Jack W Szostak
Journal:  J Am Chem Soc       Date:  2013-01-07       Impact factor: 15.419
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