Literature DB >> 15125660

N1...N3 hydrogen bonds of A:U base pairs of RNA are stronger than those of A:T base pairs of DNA.

Ioannis Vakonakis1, Andy C LiWang.   

Abstract

Trans-hydrogen-bond deuterium isotope effects of Watson-Crick A:U and A:T base pairs of 10 homologous RNA and DNA duplexes are compared. The isotope effect at 13C2 of adenosine residues due to deuterium/protium substitution at the imino H3 site, 2hDelta13C2, is larger in RNA than in DNA. The virtually consistent larger isotope effects in RNA suggest that the N1...N3 hydrogen bonds of A:U base pairs of RNA are stronger than those of the A:T base pairs of DNA.

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Year:  2004        PMID： 15125660     DOI： 10.1021/ja048981t

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  8 in total

1.  Hybridization energies of double strands composed of DNA, RNA, PNA and LNA.

Authors:  Takayuki Natsume; Yasuyuki Ishikawa; Kenichi Dedachi; Takayuki Tsukamoto; Noriyuki Kurita
Journal:  Chem Phys Lett       Date:  2007-01-26       Impact factor: 2.328

2.  N-H stretching excitations in adenosine-thymidine base pairs in solution: pair geometries, infrared line shapes, and ultrafast vibrational dynamics.

Authors:  Christian Greve; Nicholas K Preketes; Henk Fidder; Rene Costard; Benjamin Koeppe; Ismael A Heisler; Shaul Mukamel; Friedrich Temps; Erik T J Nibbering; Thomas Elsaesser
Journal:  J Phys Chem A       Date:  2013-01-07       Impact factor: 2.781

3.  Computational and empirical trans-hydrogen bond deuterium isotope shifts suggest that N1-N3 A:U hydrogen bonds of RNA are shorter than those of A:T hydrogen bonds of DNA.

Authors:  Yong-Ick Kim; Marlon N Manalo; Lisa M Peréz; Andy LiWang
Journal:  J Biomol NMR       Date:  2006-04       Impact factor: 2.835

4.  2'-Fluoro RNA shows increased Watson-Crick H-bonding strength and stacking relative to RNA: evidence from NMR and thermodynamic data.

Authors:  Amritraj Patra; Michael Paolillo; Klaus Charisse; Muthiah Manoharan; Eriks Rozners; Martin Egli
Journal:  Angew Chem Int Ed Engl       Date:  2012-10-10       Impact factor: 15.336

5.  Sensitivity of hydrogen bonds of DNA and RNA to hydration, as gauged by 1JNH measurements in ethanol-water mixtures.

Authors:  Marlon N Manalo; Xiangming Kong; Andy LiWang
Journal:  J Biomol NMR       Date:  2007-02-20       Impact factor: 2.835

6.  Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA.

Authors:  Pradeep S Pallan; Emily M Greene; Paul Andrei Jicman; Rajendra K Pandey; Muthiah Manoharan; Eriks Rozners; Martin Egli
Journal:  Nucleic Acids Res       Date:  2010-12-22       Impact factor: 16.971

7.  Stabilizing contributions of sulfur-modified nucleotides: crystal structure of a DNA duplex with 2'-O-[2-(methoxy)ethyl]-2-thiothymidines.

Authors:  Benjamin Diop-Frimpong; Thazha P Prakash; Kallanthottathil G Rajeev; Muthiah Manoharan; Martin Egli
Journal:  Nucleic Acids Res       Date:  2005-09-16       Impact factor: 16.971

8.  Mesoscopic model parametrization of hydrogen bonds and stacking interactions of RNA from melting temperatures.

Authors:  Gerald Weber
Journal:  Nucleic Acids Res       Date:  2012-10-18       Impact factor: 16.971
  8 in total

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