Literature DB >> 23050653

Synthesis and reduction kinetics of sterically shielded pyrrolidine nitroxides.

Joseph T Paletta1, Maren Pink, Bridget Foley, Suchada Rajca, Andrzej Rajca.   

Abstract

A series of sterically shielded pyrrolidine nitroxides were synthesized, and their reduction by ascorbate (vitamin C) indicate that nitroxide 3, a tetraethyl derivative of 3-carboxy-PROXYL, is reduced at the slowest rate among known nitroxides, i.e., at a 60-fold slower rate than that for 3-carboxy-PROXYL.

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Year:  2012        PMID： 23050653      PMCID： PMC3486517          DOI： 10.1021/ol302506f

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


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