Literature DB >> 22975364

The adenosine triphosphate test is a rapid and reliable audit tool to assess manual cleaning adequacy of flexible endoscope channels.

Michelle J Alfa1, Iram Fatima, Nancy Olson.   

Abstract

BACKGROUND: The study objective was to verify that the adenosine triphosphate (ATP) benchmark of <200 relative light units (RLUs) was achievable in a busy endoscopy clinic that followed the manufacturer's manual cleaning instructions.
METHODS: All channels from patient-used colonoscopes (20) and duodenoscopes (20) in a tertiary care hospital endoscopy clinic were sampled after manual cleaning and tested for residual ATP. The ATP test benchmark for adequate manual cleaning was set at <200 RLUs. The benchmark for protein was <6.4 μg/cm(2), and, for bioburden, it was <4-log10 colony-forming units/cm(2).
RESULTS: Our data demonstrated that 96% (115/120) of channels from 20 colonoscopes and 20 duodenoscopes evaluated met the ATP benchmark of <200 RLUs. The 5 channels that exceeded 200 RLUs were all elevator guide-wire channels. All 120 of the manually cleaned endoscopes tested had protein and bioburden levels that were compliant with accepted benchmarks for manual cleaning for suction-biopsy, air-water, and auxiliary water channels.
CONCLUSION: Our data confirmed that, by following the endoscope manufacturer's manual cleaning recommendations, 96% of channels in gastrointestinal endoscopes would have <200 RLUs for the ATP test kit evaluated and would meet the accepted clean benchmarks for protein and bioburden.
Copyright © 2013 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

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Year:  2012        PMID: 22975364     DOI: 10.1016/j.ajic.2012.03.015

Source DB:  PubMed          Journal:  Am J Infect Control        ISSN: 0196-6553            Impact factor:   2.918


  11 in total

1.  Surface contamination in the operating room: use of adenosine triphosphate monitoring.

Authors:  Alex Ramirez; Sanjay Mohan; Rebecca Miller; Dmitry Tumin; Joshua C Uffman; Joseph D Tobias
Journal:  J Anesth       Date:  2018-12-11       Impact factor: 2.078

Review 2.  Is peracetic acid suitable for the cleaning step of reprocessing flexible endoscopes?

Authors:  Günter Kampf; Patricia M Fliss; Heike Martiny
Journal:  World J Gastrointest Endosc       Date:  2014-09-16

3.  Scoping the scope: endoscopic evaluation of endoscope working channels with a new high-resolution inspection endoscope (with video).

Authors:  Monique T Barakat; Mohit Girotra; Robert J Huang; Subhas Banerjee
Journal:  Gastrointest Endosc       Date:  2018-02-06       Impact factor: 9.427

4.  Adenosine triphosphate bioluminescence for bacteriologic surveillance and reprocessing strategies for minimizing risk of infection transmission by duodenoscopes.

Authors:  Saurabh Sethi; Robert J Huang; Monique T Barakat; Niaz Banaei; Shai Friedland; Subhas Banerjee
Journal:  Gastrointest Endosc       Date:  2016-11-03       Impact factor: 9.427

5.  Multicenter comparative study of three "non-destructive" methods of detecting the cleanliness of the da Vinci surgical robotic instrument.

Authors:  Aiqin Chen; Xiumei Zou; Yanhua Tan; Yanhan Chen; Xinru Ye; Shuqin Hao
Journal:  Gland Surg       Date:  2021-12

Review 6.  Infectious diseases linked to cross-contamination of flexible endoscopes.

Authors:  Nikki Kenters; Elisabeth G W Huijskens; Corianne Meier; Andreas Voss
Journal:  Endosc Int Open       Date:  2015-08

7.  Monitoring of endoscope reprocessing with an adenosine triphosphate (ATP) bioluminescence method.

Authors:  Nina Parohl; Doris Stiefenhöfer; Sabine Heiligtag; Henning Reuter; Dana Dopadlik; Frank Mosel; Guido Gerken; Alexander Dechêne; Evelyn Heintschel von Heinegg; Christoph Jochum; Jan Buer; Walter Popp
Journal:  GMS Hyg Infect Control       Date:  2017-03-27

8.  Simulated-use validation of a sponge ATP method for determining the adequacy of manual cleaning of endoscope channels.

Authors:  Michelle J Alfa; Nancy Olson
Journal:  BMC Res Notes       Date:  2016-05-04

9.  Evaluation of an overnight non-culture test for detection of viable Gram-negative bacteria in endoscope channels.

Authors:  Harminder Singh; Donald R Duerksen; Gale Schultz; Carol Reidy; Pat DeGagne; Nancy Olson; Zoann Nugent; Michelle J Alfa
Journal:  Endosc Int Open       Date:  2019-01-30

10.  Evaluation of different detector types in measurement of ATP bioluminescence compared to colony counting method for measuring bacterial burden of hospital surfaces.

Authors:  Huiqiong Xu; Jiansheng Liang; Yimei Wang; Bin Wang; Tianbao Zhang; Xiaoli Liu; Lin Gong
Journal:  PLoS One       Date:  2019-09-06       Impact factor: 3.240

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