Literature DB >> 22855422

Dual-function CXCR4 antagonist polyplexes to deliver gene therapy and inhibit cancer cell invasion.

Jing Li1, Yu Zhu, Stuart T Hazeldine, Chunying Li, David Oupický.   

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Year:  2012        PMID： 22855422      PMCID： PMC3517087          DOI： 10.1002/anie.201203463

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  25 in total

Review 1.  The bicyclam AMD3100 story.

Authors:  Erik De Clercq
Journal:  Nat Rev Drug Discov       Date:  2003-07       Impact factor: 84.694

Review 2.  Cancer and the chemokine network.

Authors:  Fran Balkwill
Journal:  Nat Rev Cancer       Date:  2004-07       Impact factor: 60.716

3.  CXCL12/CXCR4 signaling activates Akt-1 and MMP-9 expression in prostate cancer cells: the role of bone microenvironment-associated CXCL12.

Authors:  Sreenivasa R Chinni; Sivasakthy Sivalogan; Zhong Dong; J Carlos Trindade Filho; Xiyun Deng; R Daniel Bonfil; Michael L Cher
Journal:  Prostate       Date:  2006-01-01       Impact factor: 4.104

4.  CXC chemokine receptor-4 antagonist blocks both growth of primary tumor and metastasis of head and neck cancer in xenograft mouse models.

Authors:  Younghyoun Yoon; Zhongxing Liang; Xin Zhang; Mison Choe; Aizhi Zhu; Heidi T Cho; Dong M Shin; Mark M Goodman; Zhuo Georgia Chen; Hyunsuk Shim
Journal:  Cancer Res       Date:  2007-08-01       Impact factor: 12.701

5.  Synthesis and structure-activity relationships of azamacrocyclic C-X-C chemokine receptor 4 antagonists: analogues containing a single azamacrocyclic ring are potent inhibitors of T-cell tropic (X4) HIV-1 replication.

Authors:  Gary J Bridger; Renato T Skerlj; Pedro E Hernandez-Abad; David E Bogucki; Zhongren Wang; Yuanxi Zhou; Susan Nan; Eva M Boehringer; Trevor Wilson; Jason Crawford; Markus Metz; Sigrid Hatse; Katrien Princen; Erik De Clercq; Dominique Schols
Journal:  J Med Chem       Date:  2010-02-11       Impact factor: 7.446

6.  New bicyclam-AZT conjugates: design, synthesis, anti-HIV evaluation, and their interaction with CXCR-4 coreceptor.

Authors:  J Dessolin; P Galea; P Vlieghe; J C Chermann; J L Kraus
Journal:  J Med Chem       Date:  1999-01-28       Impact factor: 7.446

7.  Cytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer.

Authors:  Lyndsay V Rhodes; Sarah P Short; Nicole F Neel; Virgilio A Salvo; Yun Zhu; Steven Elliott; Yongkun Wei; Dihua Yu; Menghong Sun; Shannon E Muir; Juan P Fonseca; Melyssa R Bratton; Chris Segar; Syreeta L Tilghman; Tammy Sobolik-Delmaire; Linda W Horton; Snjezana Zaja-Milatovic; Bridgette M Collins-Burow; Scott Wadsworth; Barbara S Beckman; Charles E Wood; Suzanne A Fuqua; Kenneth P Nephew; Paul Dent; Rebecca A Worthylake; Tyler J Curiel; Mien-Chie Hung; Ann Richmond; Matthew E Burow
Journal:  Cancer Res       Date:  2010-12-01       Impact factor: 12.701

Review 8.  CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment.

Authors:  Jan A Burger; Thomas J Kipps
Journal:  Blood       Date:  2005-11-03       Impact factor: 22.113

9.  Silencing of CXCR4 blocks breast cancer metastasis.

Authors:  Zhongxing Liang; Younghyoun Yoon; John Votaw; Mark M Goodman; Larry Williams; Hyunsuk Shim
Journal:  Cancer Res       Date:  2005-02-01       Impact factor: 12.701

10.  Drug-free macromolecular therapeutics: induction of apoptosis by coiled-coil-mediated cross-linking of antigens on the cell surface.

Authors:  Kuangshi Wu; Jihua Liu; Russell N Johnson; Jiyuan Yang; Jindrich Kopecek
Journal:  Angew Chem Int Ed Engl       Date:  2010-02-15       Impact factor: 15.336
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  34 in total

1.  CXCR4-Targeted Nanocarriers for Triple Negative Breast Cancers.

Authors:  Asish C Misra; Kathryn E Luker; Hakan Durmaz; Gary D Luker; Joerg Lahann
Journal:  Biomacromolecules       Date:  2015-07-22       Impact factor: 6.988

2.  Self-immolative nanoparticles for simultaneous delivery of microRNA and targeting of polyamine metabolism in combination cancer therapy.

Authors:  Ying Xie; Tracy Murray-Stewart; Yazhe Wang; Fei Yu; Jing Li; Laurence J Marton; Robert A Casero; David Oupický
Journal:  J Control Release       Date:  2016-12-23       Impact factor: 9.776

Review 3.  Bioreducible polycations in nucleic acid delivery: past, present, and future trends.

Authors:  David Oupický; Jing Li
Journal:  Macromol Biosci       Date:  2014-03-28       Impact factor: 4.979

4.  CXCR4-targeted liposomal mediated co-delivery of pirfenidone and AMD3100 for the treatment of TGFβ-induced HSC-T6 cells activation.

Authors:  Aftab Ullah; Kaikai Wang; Pengkai Wu; David Oupicky; Minjie Sun
Journal:  Int J Nanomedicine       Date:  2019-04-26

5.  Dual-action CXCR4-targeting liposomes in leukemia: function blocking and drug delivery.

Authors:  Catriona McCallion; Anna D Peters; Andrew Booth; Karen Rees-Unwin; Julie Adams; Raisa Rahi; Alain Pluen; Claire V Hutchinson; Simon J Webb; John Burthem
Journal:  Blood Adv       Date:  2019-07-23

6.  Potential of CXCR4/CXCL12 Chemokine Axis in Cancer Drug Delivery.

Authors:  Yan Wang; Ying Xie; David Oupický
Journal:  Curr Pharmacol Rep       Date:  2016-01-04

7.  Increased Survival by Pulmonary Treatment of Established Lung Metastases with Dual STAT3/CXCR4 Inhibition by siRNA Nanoemulsions.

Authors:  Zhaoting Li; Gang Chen; Ling Ding; Yixin Wang; Chenfei Zhu; Kaikai Wang; Jing Li; Minjie Sun; David Oupicky
Journal:  Mol Ther       Date:  2019-08-22       Impact factor: 11.454

Review 8.  Advances in Stimulus-Responsive Polymeric Materials for Systemic Delivery of Nucleic Acids.

Authors:  Minjie Sun; Kaikai Wang; David Oupický
Journal:  Adv Healthc Mater       Date:  2017-12-11       Impact factor: 9.933

9.  Chloroquine-Containing HPMA Copolymers as Polymeric Inhibitors of Cancer Cell Migration Mediated by the CXCR4/SDF-1 Chemokine Axis.

Authors:  Fei Yu; Ying Xie; Yan Wang; Zheng-Hong Peng; Jing Li; David Oupický
Journal:  ACS Macro Lett       Date:  2016-02-17       Impact factor: 6.903

10.  Star-shaped tetraspermine enhances cellular uptake and cytotoxicity of T-oligo in prostate cancer cells.

Authors:  Vidula Kolhatkar; Hiren Khambati; Asawari Lote; Peter Shanine; Thomas Insley; Soumyo Sen; Gnanasekar Munirathinam; Petr Král; Rohit Kolhatkar
Journal:  Pharm Res       Date:  2014-08-05       Impact factor: 4.200
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