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Literature DB >> 22851768

Extrasynaptic site of action for γ-hydroxybutyrate.

S J Enna¹.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 2012 PMID： 22851768 PMCID： PMC3421193 DOI： 10.1073/pnas.1210290109

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

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26 in total

1. Cloning and functional characterization of a gamma-hydroxybutyrate receptor identified in the human brain.

Authors: Christian Andriamampandry; Omar Taleb; Véronique Kemmel; Jean-Paul Humbert; Dominique Aunis; Michel Maitre
Journal: FASEB J Date: 2006-12-28 Impact factor: 5.191

2. Novel high-affinity and selective biaromatic 4-substituted gamma-hydroxybutyric acid (GHB) analogues as GHB ligands: design, synthesis, and binding studies.

Authors: Signe Høg; Petrine Wellendorph; Birgitte Nielsen; Karla Frydenvang; Ivar F Dahl; Hans Bräuner-Osborne; Lotte Brehm; Bente Frølund; Rasmus P Clausen
Journal: J Med Chem Date: 2008-12-25 Impact factor: 7.446

3. A specific gamma-hydroxybutyrate receptor ligand possesses both antagonistic and anticonvulsant properties.

Authors: M Maitre; V Hechler; P Vayer; S Gobaille; C D Cash; M Schmitt; J J Bourguignon
Journal: J Pharmacol Exp Ther Date: 1990-11 Impact factor: 4.030

4. Gamma-hydroxybutyric acid (GHB) and gamma-aminobutyric acidB receptor (GABABR) binding sites are distinctive from one another: molecular evidence.

Authors: Ying Wu; Saima Ali; Gholamreza Ahmadian; Chun Che Liu; Yu Tian Wang; K Michael Gibson; Andrew R Calver; Joseph Francis; Menelas N Pangalos; O Carter Snead
Journal: Neuropharmacology Date: 2004-12 Impact factor: 5.250

5. In vivo conversion of gamma-aminobutyric acid and 1,4-butanediol to gamma-hydroxybutyric acid in rat brain. Studies using stable isotopes.

Authors: O C Snead; R Furner; C C Liu
Journal: Biochem Pharmacol Date: 1989-12-15 Impact factor: 5.858

6. Effect of gamma-hydroxybutyrate and its antagonist NCS-382 on spontaneous cell firing in the prefrontal cortex of the rat.

Authors: R Godbout; P Jelenic; C Labrie; M Schmitt; J J Bourguignon
Journal: Brain Res Date: 1995-02-27 Impact factor: 3.252

Extrasynaptic site of action for γ-hydroxybutyrate.

1. Cloning and functional characterization of a gamma-hydroxybutyrate receptor identified in the human brain.

2. Novel high-affinity and selective biaromatic 4-substituted gamma-hydroxybutyric acid (GHB) analogues as GHB ligands: design, synthesis, and binding studies.

3. A specific gamma-hydroxybutyrate receptor ligand possesses both antagonistic and anticonvulsant properties.

4. Gamma-hydroxybutyric acid (GHB) and gamma-aminobutyric acidB receptor (GABABR) binding sites are distinctive from one another: molecular evidence.

5. In vivo conversion of gamma-aminobutyric acid and 1,4-butanediol to gamma-hydroxybutyric acid in rat brain. Studies using stable isotopes.

6. Effect of gamma-hydroxybutyrate and its antagonist NCS-382 on spontaneous cell firing in the prefrontal cortex of the rat.

7. Gamma-hydroxybutyric acid binding sites in rat and human brain synaptosomal membranes.

8. Anti-sedative and anti-cataleptic properties of NCS-382, a gamma-hydroxybutyrate receptor antagonist.

9. High affinity binding sites for gamma-hydroxybutyric acid in rat brain.

10. Gamma-hydroxybutyrate hyperpolarizes hippocampal neurones by activating GABAB receptors.