Literature DB >> 22815360

DanteR: an extensible R-based tool for quantitative analysis of -omics data.

Tom Taverner1, Yuliya V Karpievitch, Ashoka D Polpitiya, Joseph N Brown, Alan R Dabney, Gordon A Anderson, Richard D Smith.   

Abstract

MOTIVATION: The size and complex nature of mass spectrometry-based proteomics datasets motivate development of specialized software for statistical data analysis and exploration. We present DanteR, a graphical R package that features extensive statistical and diagnostic functions for quantitative proteomics data analysis, including normalization, imputation, hypothesis testing, interactive visualization and peptide-to-protein rollup. More importantly, users can easily extend the existing functionality by including their own algorithms under the Add-On tab. AVAILABILITY: DanteR and its associated user guide are available for download free of charge at http://omics.pnl.gov/software/. We have an updated binary source for the DanteR package up on our website together with a vignettes document. For Windows, a single click automatically installs DanteR along with the R programming environment. For Linux and Mac OS X, users must install R and then follow instructions on the DanteR website for package installation. CONTACT: rds@pnnl.gov.

Mesh:

Substances:

Year:  2012        PMID: 22815360      PMCID: PMC3436848          DOI: 10.1093/bioinformatics/bts449

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  6 in total

1.  Missing value estimation methods for DNA microarrays.

Authors:  O Troyanskaya; M Cantor; G Sherlock; P Brown; T Hastie; R Tibshirani; D Botstein; R B Altman
Journal:  Bioinformatics       Date:  2001-06       Impact factor: 6.937

2.  Normalization approaches for removing systematic biases associated with mass spectrometry and label-free proteomics.

Authors:  Stephen J Callister; Richard C Barry; Joshua N Adkins; Ethan T Johnson; Wei-Jun Qian; Bobbie-Jo M Webb-Robertson; Richard D Smith; Mary S Lipton
Journal:  J Proteome Res       Date:  2006-02       Impact factor: 4.466

3.  A statistical framework for protein quantitation in bottom-up MS-based proteomics.

Authors:  Yuliya Karpievitch; Jeff Stanley; Thomas Taverner; Jianhua Huang; Joshua N Adkins; Charles Ansong; Fred Heffron; Thomas O Metz; Wei-Jun Qian; Hyunjin Yoon; Richard D Smith; Alan R Dabney
Journal:  Bioinformatics       Date:  2009-06-17       Impact factor: 6.937

4.  Normalization of peak intensities in bottom-up MS-based proteomics using singular value decomposition.

Authors:  Yuliya V Karpievitch; Thomas Taverner; Joshua N Adkins; Stephen J Callister; Gordon A Anderson; Richard D Smith; Alan R Dabney
Journal:  Bioinformatics       Date:  2009-07-14       Impact factor: 6.937

5.  DAnTE: a statistical tool for quantitative analysis of -omics data.

Authors:  Ashoka D Polpitiya; Wei-Jun Qian; Navdeep Jaitly; Vladislav A Petyuk; Joshua N Adkins; David G Camp; Gordon A Anderson; Richard D Smith
Journal:  Bioinformatics       Date:  2008-05-03       Impact factor: 6.937

Review 6.  A survey of computational methods and error rate estimation procedures for peptide and protein identification in shotgun proteomics.

Authors:  Alexey I Nesvizhskii
Journal:  J Proteomics       Date:  2010-09-08       Impact factor: 4.044

  6 in total
  61 in total

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Authors:  Sonya M Clarkson; Richard J Giannone; Donna M Kridelbaugh; James G Elkins; Adam M Guss; Joshua K Michener
Journal:  Appl Environ Microbiol       Date:  2017-08-31       Impact factor: 4.792

2.  Understanding and Eliminating the Detrimental Effect of Thiamine Deficiency on the Oleaginous Yeast Yarrowia lipolytica.

Authors:  Caleb Walker; Seunghyun Ryu; Richard J Giannone; Sergio Garcia; Cong T Trinh
Journal:  Appl Environ Microbiol       Date:  2020-01-21       Impact factor: 4.792

3.  Silymarin Suppresses Cellular Inflammation By Inducing Reparative Stress Signaling.

Authors:  Erica S Lovelace; Jessica Wagoner; James MacDonald; Theo Bammler; Jacob Bruckner; Jessica Brownell; Richard P Beyer; Erika M Zink; Young-Mo Kim; Jennifer E Kyle; Bobbie-Jo M Webb-Robertson; Katrina M Waters; Thomas O Metz; Federico Farin; Nicholas H Oberlies; Stephen J Polyak
Journal:  J Nat Prod       Date:  2015-07-17       Impact factor: 4.050

4.  Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention.

Authors:  Ernesto S Nakayasu; Farooq Syed; Sarah A Tersey; Marina A Gritsenko; Hugh D Mitchell; Chi Yuet Chan; Ercument Dirice; Jean-Valery Turatsinze; Yi Cui; Rohit N Kulkarni; Decio L Eizirik; Wei-Jun Qian; Bobbie-Jo M Webb-Robertson; Carmella Evans-Molina; Raghavendra G Mirmira; Thomas O Metz
Journal:  Cell Metab       Date:  2020-01-09       Impact factor: 27.287

5.  Proteomic profiling and pathway analysis of the response of rat renal proximal convoluted tubules to metabolic acidosis.

Authors:  Kevin L Schauer; Dana M Freund; Jessica E Prenni; Norman P Curthoys
Journal:  Am J Physiol Renal Physiol       Date:  2013-06-26

6.  Methods for Proteomic Analyses of Mycobacteria.

Authors:  Carolina Mehaffy; Megan Lucas; Nicole A Kruh-Garcia; Karen M Dobos
Journal:  Methods Mol Biol       Date:  2021

Review 7.  Review, evaluation, and discussion of the challenges of missing value imputation for mass spectrometry-based label-free global proteomics.

Authors:  Bobbie-Jo M Webb-Robertson; Holli K Wiberg; Melissa M Matzke; Joseph N Brown; Jing Wang; Jason E McDermott; Richard D Smith; Karin D Rodland; Thomas O Metz; Joel G Pounds; Katrina M Waters
Journal:  J Proteome Res       Date:  2015-04-22       Impact factor: 4.466

8.  The effects of nonignorable missing data on label-free mass spectrometry proteomics experiments.

Authors:  Jonathon J O'Brien; Harsha P Gunawardena; Joao A Paulo; Xian Chen; Joseph G Ibrahim; Steven P Gygi; Bahjat F Qaqish
Journal:  Ann Appl Stat       Date:  2018-11-13       Impact factor: 2.083

9.  High-Fat Diets Alter the Modulatory Effects of Xenobiotics on Cytochrome P450 Activities.

Authors:  Natalie C Sadler; Bobbie-Jo M Webb-Robertson; Therese R Clauss; Joel G Pounds; Richard Corley; Aaron T Wright
Journal:  Chem Res Toxicol       Date:  2018-05-04       Impact factor: 3.739

10.  The effects of micronutrient deficiencies on bacterial species from the human gut microbiota.

Authors:  Matthew C Hibberd; Meng Wu; Dmitry A Rodionov; Xiaoqing Li; Jiye Cheng; Nicholas W Griffin; Michael J Barratt; Richard J Giannone; Robert L Hettich; Andrei L Osterman; Jeffrey I Gordon
Journal:  Sci Transl Med       Date:  2017-05-17       Impact factor: 17.956

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