| Literature DB >> 18453552 |
Ashoka D Polpitiya1, Wei-Jun Qian, Navdeep Jaitly, Vladislav A Petyuk, Joshua N Adkins, David G Camp, Gordon A Anderson, Richard D Smith.
Abstract
UNLABELLED: Data Analysis Tool Extension (DAnTE) is a statistical tool designed to address challenges associated with quantitative bottom-up, shotgun proteomics data. This tool has also been demonstrated for microarray data and can easily be extended to other high-throughput data types. DAnTE features selected normalization methods, missing value imputation algorithms, peptide-to-protein rollup methods, an extensive array of plotting functions and a comprehensive hypothesis-testing scheme that can handle unbalanced data and random effects. The graphical user interface (GUI) is designed to be very intuitive and user friendly. AVAILABILITY: DAnTE may be downloaded free of charge at http://omics.pnl.gov/software/. SUPPLEMENTARY INFORMATION: An example dataset with instructions on how to perform a series of analysis steps is available at http://omics.pnl.gov/software/Mesh：
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Year: 2008 PMID： 18453552 PMCID： PMC2692489 DOI： 10.1093/bioinformatics/btn217
Source DB: PubMed Journal: Bioinformatics ISSN： 1367-4803 Impact factor: 6.937