Literature DB >> 22729337

Treatment of dry age-related macular degeneration with dobesilate.

P Cuevas1, L A Outeiriño, J Angulo, G Giménez-Gallego.   

Abstract

The authors present anatomical and functional evidences of dry age-macular degeneration improvement, after intravitreal treatment with dobesilate. Main outcomes measures were normalisation of retinal structure and function, assessed by optical coherence tomography, fundus-monitored microperimetry, electrophysiology and visual acuity. The effect might be related to the normalisation of the outer retinal architecture.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22729337      PMCID： PMC3387461          DOI： 10.1136/bcr.02.2012.5942

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN： 1757-790X


  35 in total

Review 1.  Histopathology of age-related macular degeneration.

Authors:  W R Green
Journal:  Mol Vis       Date:  1999-11-03       Impact factor: 2.367

2.  Light-induced migration of retinal microglia into the subretinal space.

Authors:  T F Ng; J W Streilein
Journal:  Invest Ophthalmol Vis Sci       Date:  2001-12       Impact factor: 4.799

3.  Fibroblast growth factor-1 (FGF-1) enhances IL-2 production and nuclear translocation of NF-kappaB in FGF receptor-bearing Jurkat T cells.

Authors:  V M Byrd; D W Ballard; G G Miller; J W Thomas
Journal:  J Immunol       Date:  1999-05-15       Impact factor: 5.422

Review 4.  Evolving guidelines for intravitreous injections.

Authors:  Lloyd P Aiello; Alexander J Brucker; Stanley Chang; Emmett T Cunningham; Donald J D'Amico; Harry W Flynn; Lisa R Grillone; Steve Hutcherson; Jeffrey M Liebmann; Terrence P O'Brien; Ingrid U Scott; Richard F Spaide; Christopher Ta; Michael T Trese
Journal:  Retina       Date:  2004-10       Impact factor: 4.256

5.  Basic FGF in astroglial, microglial, and neuronal cultures: characterization of binding sites and modulation of release by lymphokines and trophic factors.

Authors:  D M Araujo; C W Cotman
Journal:  J Neurosci       Date:  1992-05       Impact factor: 6.167

6.  Assessment of the anti-inflammatory action of calcium dobesilate. Effect on macrophages attaching to subcutaneously implanted coverslips in guinea pigs.

Authors:  N B Piller
Journal:  Arzneimittelforschung       Date:  1990-06

Review 7.  Platelet-activating factor--a powerful lipid autacoid possibly involved in microangiopathy.

Authors:  F Bussolino; P Biffignandi; P Arese
Journal:  Acta Haematol       Date:  1986       Impact factor: 2.195

8.  Immunolocalization of fibroblast growth factor-1 (FGF-1), its receptor (FGFR-1), and fibroblast-specific protein-1 (FSP-1) in inflammatory renal disease.

Authors:  Michele Rossini; Boonyarit Cheunsuchon; Ellen Donnert; Li-Jun Ma; James W Thomas; Eric G Neilson; Agnes B Fogo
Journal:  Kidney Int       Date:  2005-12       Impact factor: 10.612

9.  Basic FGF and FGF receptor 1 are expressed in microglia during experimental autoimmune encephalomyelitis: temporally distinct expression of midkine and pleiotrophin.

Authors:  X Liu; G A Mashour; H F Webster; A Kurtz
Journal:  Glia       Date:  1998-12       Impact factor: 7.452

10.  Brain-derived acidic fibroblast growth factor: complete amino acid sequence and homologies.

Authors:  G Gimenez-Gallego; J Rodkey; C Bennett; M Rios-Candelore; J DiSalvo; K Thomas
Journal:  Science       Date:  1985-12-20       Impact factor: 47.728
View more
  4 in total

1.  Chronic cystoid macular oedema treated with intravitreal dobesilate.

Authors:  Pedro Cuevas; Luis A Outeiriño; Javier Angulo; Guillermo Giménez-Gallego
Journal:  BMJ Case Rep       Date:  2012-07-09

2.  Treatment of Stargardt disease with dobesilate.

Authors:  Pedro Cuevas; Luis A Outeiriño; Javier Angulo; Guillermo Giménez-Gallego
Journal:  BMJ Case Rep       Date:  2012-10-12

3.  Intravitreal dobesilate in the treatment of choroidal neovascularisation associated with age-related macular degeneration: report of two cases.

Authors:  Pedro Cuevas; Luis Outeiriño; Carlos Azanza; Guillermo Giménez-Gallego
Journal:  BMJ Case Rep       Date:  2012-09-03

4.  Diacetyloxyl derivatization of the fibroblast growth factor inhibitor dobesilate enhances its anti-inflammatory, anti-angiogenic and anti-tumoral activities.

Authors:  Javier Angulo; Pedro Cuevas; Begoña Cuevas; Mohammad El Youssef; Argentina Fernández; Eduardo Martínez-Salamanca; Rocío González-Corrochano; Guillermo Giménez-Gallego
Journal:  J Transl Med       Date:  2015-02-01       Impact factor: 5.531
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.