Literature DB >> 23076703

Treatment of Stargardt disease with dobesilate.

Pedro Cuevas1, Luis A Outeiriño, Javier Angulo, Guillermo Giménez-Gallego.   

Abstract

Stargardt disease is a common inherited macular degeneration characterised by a significant loss in the central vision during the first or second decade of the life. Bilateral atrophic changes in the central retina are associated with degeneration of photoreceptors and underlying retinal pigment epithelium, and yellow flecks are extending from the macula. We present a patient with Stargardt disease treated with an intravitreal injection of dobesilate, showing an improvement of visual acuity 4 weeks after treatment.

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Year:  2012        PMID： 23076703      PMCID： PMC4544153          DOI： 10.1136/bcr-2012-007128

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN： 1757-790X


  34 in total

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  1 in total

1.  Diacetyloxyl derivatization of the fibroblast growth factor inhibitor dobesilate enhances its anti-inflammatory, anti-angiogenic and anti-tumoral activities.

Authors:  Javier Angulo; Pedro Cuevas; Begoña Cuevas; Mohammad El Youssef; Argentina Fernández; Eduardo Martínez-Salamanca; Rocío González-Corrochano; Guillermo Giménez-Gallego
Journal:  J Transl Med       Date:  2015-02-01       Impact factor: 5.531
  1 in total

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