Literature DB >> 4071057

Brain-derived acidic fibroblast growth factor: complete amino acid sequence and homologies.

G Gimenez-Gallego, J Rodkey, C Bennett, M Rios-Candelore, J DiSalvo, K Thomas.   

Abstract

Bovine brain-derived acidic fibroblast growth factor (aFGF) is a protein mitogen originally identified in partially purified preparations of whole brain. The protein was purified to homogeneity and shown to be a potent vascular endothelial cell mitogen in culture and angiogenic substance in vivo. The homology of aFGF to human interleukin-1 beta was inferred from partial sequence data. The complete amino acid sequence of aFGF has now been determined and observed to be similar to both basic FGF and interleukin-1's. A neuropeptide-like sequence, flanked by basic dipeptides, was observed within the aFGF sequence.

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Year:  1985        PMID： 4071057     DOI： 10.1126/science.4071057

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  54 in total

Review 1.  Molecular mechanisms regulating motor neuron development and degeneration.

Authors:  T J Kilpatrick; M Soilu-Hänninen
Journal:  Mol Neurobiol       Date:  1999-06       Impact factor: 5.590

Review 2.  Growth factors in the ovary.

Authors:  G Giordano; A Barreca; F Minuto
Journal:  J Endocrinol Invest       Date:  1992-10       Impact factor: 4.256

3.  Treatment of dry age-related macular degeneration with dobesilate.

Authors:  P Cuevas; L A Outeiriño; J Angulo; G Giménez-Gallego
Journal:  BMJ Case Rep       Date:  2012-06-21

Review 4.  Growth factors and the skeletal system.

Authors:  E Canalis; T L McCarthy; M Centrella
Journal:  J Endocrinol Invest       Date:  1989-09       Impact factor: 4.256

5.  Characterization of release of basic fibroblast growth factor from bovine retinal endothelial cells in monolayer cultures.

Authors:  R A Brooks; J M Burrin; E M Kohner
Journal:  Biochem J       Date:  1991-05-15       Impact factor: 3.857

Review 6.  Cellular signaling by fibroblast growth factors (FGFs) and their receptors (FGFRs) in male reproduction.

Authors:  Leanne M Cotton; Moira K O'Bryan; Barry T Hinton
Journal:  Endocr Rev       Date:  2008-01-23       Impact factor: 19.871

7.  Molecular cloning of a cDNA encoding a human macrophage migration inhibitory factor.

Authors:  W Y Weiser; P A Temple; J S Witek-Giannotti; H G Remold; S C Clark; J R David
Journal:  Proc Natl Acad Sci U S A       Date:  1989-10       Impact factor: 11.205

8.  Three-dimensional structure of human basic fibroblast growth factor, a structural homolog of interleukin 1 beta.

Authors:  J D Zhang; L S Cousens; P J Barr; S R Sprang
Journal:  Proc Natl Acad Sci U S A       Date:  1991-04-15       Impact factor: 11.205

9.  Post-transcriptional regulation of interleukin 1 alpha in various strains of young and senescent human umbilical vein endothelial cells.

Authors:  S Garfinkel; S Brown; J H Wessendorf; T Maciag
Journal:  Proc Natl Acad Sci U S A       Date:  1994-02-15       Impact factor: 11.205

10.  Basic fibroblast growth factor is a beta-rich protein.

Authors:  C S Wu; S A Thompson; J T Yang
Journal:  J Protein Chem       Date:  1991-08
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