Literature DB >> 22726433

RNA polymerase backtracking in gene regulation and genome instability.

Evgeny Nudler1.   

Abstract

RNA polymerase is a ratchet machine that oscillates between productive and backtracked states at numerous DNA positions. Since its first description 15 years ago, backtracking--the reversible sliding of RNA polymerase along DNA and RNA--has been implicated in many critical processes in bacteria and eukaryotes, including the control of transcription elongation, pausing, termination, fidelity, and genome instability.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID： 22726433      PMCID： PMC3815583          DOI： 10.1016/j.cell.2012.06.003

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  102 in total

1.  Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation.

Authors:  Daniel A Gilchrist; Gilberto Dos Santos; David C Fargo; Bin Xie; Yuan Gao; Leping Li; Karen Adelman
Journal:  Cell       Date:  2010-11-12       Impact factor: 41.582

2.  Global analysis of nascent RNA reveals transcriptional pausing in terminal exons.

Authors:  Fernando Carrillo Oesterreich; Stephan Preibisch; Karla M Neugebauer
Journal:  Mol Cell       Date:  2010-11-24       Impact factor: 17.970

3.  Structural basis of RNA polymerase II backtracking, arrest and reactivation.

Authors:  Alan C M Cheung; Patrick Cramer
Journal:  Nature       Date:  2011-02-23       Impact factor: 49.962

4.  Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor protein.

Authors:  Shunsuke Tagami; Shun-Ichi Sekine; Thirumananseri Kumarevel; Nobumasa Hino; Yuko Murayama; Syunsuke Kamegamori; Masaki Yamamoto; Kensaku Sakamoto; Shigeyuki Yokoyama
Journal:  Nature       Date:  2010-12-01       Impact factor: 49.962

5.  Mechanism of transcription termination: PTRF interacts with the largest subunit of RNA polymerase I and dissociates paused transcription complexes from yeast and mouse.

Authors:  P Jansa; I Grummt
Journal:  Mol Gen Genet       Date:  1999-10

6.  A backtrack-inducing sequence is an essential component of Escherichia coli σ(70)-dependent promoter-proximal pausing.

Authors:  Sarah A Perdue; Jeffrey W Roberts
Journal:  Mol Microbiol       Date:  2010-09-30       Impact factor: 3.501

7.  Transcriptional activators enhance polyadenylation of mRNA precursors.

Authors:  Takashi Nagaike; Charlotte Logan; Ikuko Hotta; Orit Rozenblatt-Rosen; Matthew Meyerson; James L Manley
Journal:  Mol Cell       Date:  2011-02-18       Impact factor: 17.970

8.  Nascent transcript sequencing visualizes transcription at nucleotide resolution.

Authors:  L Stirling Churchman; Jonathan S Weissman
Journal:  Nature       Date:  2011-01-20       Impact factor: 49.962

9.  Recombination phenotypes of Escherichia coli greA mutants.

Authors:  Anthony R Poteete
Journal:  BMC Mol Biol       Date:  2011-03-31       Impact factor: 2.946

10.  Splicing-dependent RNA polymerase pausing in yeast.

Authors:  Ross D Alexander; Steven A Innocente; J David Barrass; Jean D Beggs
Journal:  Mol Cell       Date:  2010-11-24       Impact factor: 19.328
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  134 in total

Review 1.  Fail-safe transcription termination: Because one is never enough.

Authors:  Jean-François Lemay; François Bachand
Journal:  RNA Biol       Date:  2015       Impact factor: 4.652

2.  Expanded GAA repeats impede transcription elongation through the FXN gene and induce transcriptional silencing that is restricted to the FXN locus.

Authors:  Yanjie Li; Yue Lu; Urszula Polak; Kevin Lin; Jianjun Shen; Jennifer Farmer; Lauren Seyer; Angela D Bhalla; Natalia Rozwadowska; David R Lynch; Jill Sergesketter Butler; Marek Napierala
Journal:  Hum Mol Genet       Date:  2015-09-23       Impact factor: 6.150

3.  Mfd as a central partner of transcription coupled repair.

Authors:  Jordan Monnet; Wilfried Grange; Terence R Strick; Nicolas Joly
Journal:  Transcription       Date:  2013-05-16

Review 4.  The Clash of Macromolecular Titans: Replication-Transcription Conflicts in Bacteria.

Authors:  Kevin S Lang; Houra Merrikh
Journal:  Annu Rev Microbiol       Date:  2018-06-01       Impact factor: 15.500

5.  Interaction with Single-stranded DNA-binding Protein Stimulates Escherichia coli Ribonuclease HI Enzymatic Activity.

Authors:  Christine Petzold; Aimee H Marceau; Katherine H Miller; Susan Marqusee; James L Keck
Journal:  J Biol Chem       Date:  2015-04-22       Impact factor: 5.157

Review 6.  Ubiquitous transcription factors display structural plasticity and diverse functions: NusG proteins - Shifting shapes and paradigms.

Authors:  Monali NandyMazumdar; Irina Artsimovitch
Journal:  Bioessays       Date:  2015-01-15       Impact factor: 4.345

7.  Reading of the non-template DNA by transcription elongation factors.

Authors:  Vladimir Svetlov; Evgeny Nudler
Journal:  Mol Microbiol       Date:  2018-08       Impact factor: 3.501

Review 8.  Transcription termination by the eukaryotic RNA polymerase III.

Authors:  Aneeshkumar G Arimbasseri; Keshab Rijal; Richard J Maraia
Journal:  Biochim Biophys Acta       Date:  2012-10-23

9.  Rho-dependent transcription termination is essential to prevent excessive genome-wide R-loops in Escherichia coli.

Authors:  J Krishna Leela; Aisha H Syeda; K Anupama; J Gowrishankar
Journal:  Proc Natl Acad Sci U S A       Date:  2012-12-18       Impact factor: 11.205

Review 10.  Molecular traffic jams on DNA.

Authors:  Ilya J Finkelstein; Eric C Greene
Journal:  Annu Rev Biophys       Date:  2013-02-28       Impact factor: 12.981
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