BACKGROUND: capsule endoscopy (CE) has revolutionized the study of small bowel. One major drawback of this technique is that we cannot interfere with image acquisition process. Therefore, the development of new software tools that could modify the images and increase both detection and diagnosis of small-bowel lesions would be very useful. The Flexible Spectral Imaging Color Enhancement (FICE) that allows for virtual chromoendoscopy is one of these software tools. AIMS: to evaluate the reproducibility and diagnostic accuracy of the FICE system in CE. METHODS: this prospective study involved 20 patients. First, four physicians interpreted 150 static FICE images and the overall agreement between them was determined using the Fleiss Kappa Test. Second, two experienced gastroenterologists, blinded to each other results, analyzed the complete 20 video streams. One interpreted conventional capsule videos and the other, the CE-FICE videos at setting 2. All findings were reported, regardless of their clinical value. Non-concordant findings between both interpretations were analyzed by a consensus panel of four gastroenterologists who reached a final result (positive or negative finding). RESULTS: in the first arm of the study the overall concordance between the four gastroenterologists was substantial (0.650). In the second arm, the conventional mode identified 75 findings and the CE-FICE mode 95. The CE-FICE mode did not miss any lesions identified by the conventional mode and allowed the identification of a higher number of angiodysplasias (35 vs 32), and erosions (41 vs. 24). CONCLUSIONS: there is reproducibility for the interpretation of CE-FICE images between different observers experienced in conventional CE. The use of virtual chromoendoscopy in CE seems to increase its diagnostic accuracy by highlighting small bowel erosions and angiodysplasias that weren´t identified by the conventional mode.
BACKGROUND: capsule endoscopy (CE) has revolutionized the study of small bowel. One major drawback of this technique is that we cannot interfere with image acquisition process. Therefore, the development of new software tools that could modify the images and increase both detection and diagnosis of small-bowel lesions would be very useful. The Flexible Spectral Imaging Color Enhancement (FICE) that allows for virtual chromoendoscopy is one of these software tools. AIMS: to evaluate the reproducibility and diagnostic accuracy of the FICE system in CE. METHODS: this prospective study involved 20 patients. First, four physicians interpreted 150 static FICE images and the overall agreement between them was determined using the Fleiss Kappa Test. Second, two experienced gastroenterologists, blinded to each other results, analyzed the complete 20 video streams. One interpreted conventional capsule videos and the other, the CE-FICE videos at setting 2. All findings were reported, regardless of their clinical value. Non-concordant findings between both interpretations were analyzed by a consensus panel of four gastroenterologists who reached a final result (positive or negative finding). RESULTS: in the first arm of the study the overall concordance between the four gastroenterologists was substantial (0.650). In the second arm, the conventional mode identified 75 findings and the CE-FICE mode 95. The CE-FICE mode did not miss any lesions identified by the conventional mode and allowed the identification of a higher number of angiodysplasias (35 vs 32), and erosions (41 vs. 24). CONCLUSIONS: there is reproducibility for the interpretation of CE-FICE images between different observers experienced in conventional CE. The use of virtual chromoendoscopy in CE seems to increase its diagnostic accuracy by highlighting small bowel erosions and angiodysplasias that weren´t identified by the conventional mode.
Authors: Cristiano Spada; Deirdre McNamara; Edward J Despott; Samuel Adler; Brooks D Cash; Ignacio Fernández-Urién; Hrvoje Ivekovic; Martin Keuchel; Mark McAlindon; Jean-Christophe Saurin; Simon Panter; Cristina Bellisario; Silvia Minozzi; Carlo Senore; Cathy Bennett; Michael Bretthauer; Mario Dinis-Ribeiro; Dirk Domagk; Cesare Hassan; Michal F Kaminski; Colin J Rees; Roland Valori; Raf Bisschops; Matthew D Rutter Journal: United European Gastroenterol J Date: 2019-05-15 Impact factor: 4.623
Authors: José Cotter; Joana Magalhães; Francisca Dias de Castro; Mara Barbosa; Pedro Boal Carvalho; Sílvia Leite; Maria João Moreira; Bruno Rosa Journal: World J Gastrointest Endosc Date: 2014-08-16
Authors: Joana Ribeiro da Silva; Rolando Pinho; Adélia Rodrigues; Ana Ponte; Jaime Rodrigues; Mafalda Sousa; João Carvalho Journal: GE Port J Gastroenterol Date: 2018-01-17
Authors: Tiago Cúrdia Gonçalves; Joana Magalhães; Pedro Boal Carvalho; Maria João Moreira; Bruno Rosa; José Cotter Journal: Diagn Ther Endosc Date: 2014-03-17
Authors: Mihai Rimbaş; Denise Carmen Mihaela Zahiu; Andrei Mihai Voiosu; Theodor Alexandru Voiosu; Alina Ana-Maria Zlate; Roxana Dinu; Domenico Galasso; Leonardo Minelli Grazioli; Mariachiara Campanale; Federico Barbaro; Bogdan Radu Mateescu; Bogdan Busuioc; Tiberiu Iordache; Oana Dolofan; Adelina Maria Popescu; Vasile Daniel Balaban; Mircea Mihai Raducan; Cristiano Spada; Cristian Răsvan Băicuş; Guido Costamagna Journal: Endosc Int Open Date: 2016-05-12