OBJECTIVE: To determine if patients, less than 40 years of age with or without day 5 cryopreservation (d5 cryo), compromise their pregnancy rate (PR) by choosing an eSBT. DESIGN: Retrospective analysis SETTING: University IVF center PATIENTS: 2,203 non-donor fresh IVF cycles in women <40 years of age from January 2004 to January 2010. INTERVENTIONS: None MAIN OUTCOME MEASURE(S): Eggs retrieved, Embryos cryopreserved, Implantation Rates, Clinical Pregnancy Rates, Live Birth Rates, Spontaneous Abortion Rates RESULTS: Pregnancy outcomes in women <40 years with or without d5 cryo were compared according to whether patients underwent an eSBT versus a 2BT in non-donor fresh IVF cycles. Overall, eSBT was associated with elimination of twinning while maintaining a high clinical pregnancy rate in both groups with d5 cryo (75 % eSBT versus 72 % 2BT) and groups without d5 cryo (48 % eSBT versus 56 % 2BT). CONCLUSIONS: In this study, patients <40 years of age have eliminated twinning by electively choosing to transfer a single blastocyst without compromising their PR if embryos are available for d5 cryo, and suffer only a non-statistically significant drop in their PR if there are no embryos available for d5 cryo in exchange for the benefit of eliminating the obstetrical risk of twinning.
OBJECTIVE: To determine if patients, less than 40 years of age with or without day 5 cryopreservation (d5 cryo), compromise their pregnancy rate (PR) by choosing an eSBT. DESIGN: Retrospective analysis SETTING: University IVF center PATIENTS: 2,203 non-donor fresh IVF cycles in women <40 years of age from January 2004 to January 2010. INTERVENTIONS: None MAIN OUTCOME MEASURE(S): Eggs retrieved, Embryos cryopreserved, Implantation Rates, Clinical Pregnancy Rates, Live Birth Rates, Spontaneous Abortion Rates RESULTS: Pregnancy outcomes in women <40 years with or without d5 cryo were compared according to whether patients underwent an eSBT versus a 2BT in non-donor fresh IVF cycles. Overall, eSBT was associated with elimination of twinning while maintaining a high clinical pregnancy rate in both groups with d5 cryo (75 % eSBT versus 72 % 2BT) and groups without d5 cryo (48 % eSBT versus 56 % 2BT). CONCLUSIONS: In this study, patients <40 years of age have eliminated twinning by electively choosing to transfer a single blastocyst without compromising their PR if embryos are available for d5 cryo, and suffer only a non-statistically significant drop in their PR if there are no embryos available for d5 cryo in exchange for the benefit of eliminating the obstetrical risk of twinning.
Authors: Jan Gerris; Diane De Neubourg; Katelijne Mangelschots; Eric Van Royen; Miet Vercruyssen; Jorge Barudy-Vasquez; Marion Valkenburg; Greet Ryckaert Journal: Hum Reprod Date: 2002-10 Impact factor: 6.918
Authors: Ann I Scher; Bev Petterson; Eve Blair; Jonas H Ellenberg; Judy K Grether; Eric Haan; Dinah S Reddihough; Marshalyn Yeargin-Allsopp; Karin B Nelson Journal: Pediatr Res Date: 2002-11 Impact factor: 3.756
Authors: H Martikainen; A Tiitinen; C Tomás; J Tapanainen; M Orava; L Tuomivaara; S Vilska; C Hydén-Granskog; O Hovatta Journal: Hum Reprod Date: 2001-09 Impact factor: 6.918
Authors: M D Kogan; G R Alexander; M Kotelchuck; M F MacDorman; P Buekens; J A Martin; E Papiernik Journal: JAMA Date: 2000-07-19 Impact factor: 56.272
Authors: Raja Z Karaki; Sadoon S Samarraie; Nagham A Younis; Tarek M Lahloub; Mohammed H Ibrahim Journal: Fertil Steril Date: 2002-01 Impact factor: 7.329
Authors: Micah J Hill; Kevin S Richter; Ryan J Heitmann; Terrance D Lewis; Alan H DeCherney; James R Graham; Eric Widra; Michael J Levy Journal: Fertil Steril Date: 2013-02-20 Impact factor: 7.329