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4 in total

1. Failure of iniparib to inhibit poly(ADP-Ribose) polymerase in vitro.

Authors: Anand G Patel; Silvana B De Lorenzo; Karen S Flatten; Guy G Poirier; Scott H Kaufmann
Journal: Clin Cancer Res Date: 2012-01-30 Impact factor: 12.531

2. Trial watch: Phase II failures: 2008-2010.

Authors: John Arrowsmith
Journal: Nat Rev Drug Discov Date: 2011-05 Impact factor: 84.694

3. Iniparib nonselectively modifies cysteine-containing proteins in tumor cells and is not a bona fide PARP inhibitor.

Authors: Xuesong Liu; Yan Shi; David X Maag; Joann P Palma; Melanie J Patterson; Paul A Ellis; Bruce W Surber; Damien B Ready; Niru B Soni; Uri S Ladror; Allison J Xu; Ramesh Iyer; John E Harlan; Larry R Solomon; Cherrie K Donawho; Thomas D Penning; Eric F Johnson; Alexander R Shoemaker
Journal: Clin Cancer Res Date: 2011-11-29 Impact factor: 12.531

4. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial.

Authors: Andrew Tutt; Mark Robson; Judy E Garber; Susan M Domchek; M William Audeh; Jeffrey N Weitzel; Michael Friedlander; Banu Arun; Niklas Loman; Rita K Schmutzler; Andrew Wardley; Gillian Mitchell; Helena Earl; Mark Wickens; James Carmichael
Journal: Lancet Date: 2010-07-06 Impact factor: 79.321

4 in total

17 in total

Review 1. Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review.

Authors: Peter Csermely; Tamás Korcsmáros; Huba J M Kiss; Gábor London; Ruth Nussinov
Journal: Pharmacol Ther Date: 2013-02-04 Impact factor: 12.310

Review 2. Phenotypic screening in cancer drug discovery - past, present and future.

Authors: John G Moffat; Joachim Rudolph; David Bailey
Journal: Nat Rev Drug Discov Date: 2014-07-18 Impact factor: 84.694

3. New surface radiolabeling schemes of super paramagnetic iron oxide nanoparticles (SPIONs) for biodistribution studies.

Authors: Prakash D Nallathamby; Ninell P Mortensen; Heather A Palko; Mike Malfatti; Catherine Smith; James Sonnett; Mitchel J Doktycz; Baohua Gu; Ryan K Roeder; Wei Wang; Scott T Retterer
Journal: Nanoscale Date: 2015-04-21 Impact factor: 7.790

4. Chemotherapy in Patients with Anthracycline- and Taxane-Pretreated Metastatic Breast Cancer: An Overview.

Authors: Eleni Andreopoulou; Joseph A Sparano
Journal: Curr Breast Cancer Rep Date: 2013-03-01

5. PARP-mediated repair, homologous recombination, and back-up non-homologous end joining-like repair of single-strand nicks.

Authors: Michael J Metzger; Barry L Stoddard; Raymond J Monnat
Journal: DNA Repair (Amst) Date: 2013-05-16

Review 10. Application of Computational Biology and Artificial Intelligence Technologies in Cancer Precision Drug Discovery.

Authors: Nagasundaram Nagarajan; Edward K Y Yapp; Nguyen Quoc Khanh Le; Balu Kamaraj; Abeer Mohammed Al-Subaie; Hui-Yuan Yeh
Journal: Biomed Res Int Date: 2019-11-11 Impact factor: 3.411

Drug candidates derailed in case of mistaken identity.