Literature DB >> 22402957

Effect of surgical approach on 30-day mortality and morbidity after elective colectomy: a NSQIP study.

Molly M Cone1, Daniel O Herzig, Brian S Diggs, Jennifer D Rea, Karin M Hardiman, Kim C Lu.   

Abstract

PURPOSE: The aim of this study was to evaluate the laparoscopic approach and pre- and postoperative conditions as predictors of 30-day mortality and morbidity in elective colectomy.
METHODS: Elective colectomies were identified in the 2005-2008 American College of Surgeons National Surgical Quality Improvement Program database. Multivariate logistic regression was used to model 30-day mortality and morbidity following elective colectomy. Propensity scores were calculated to decrease selection bias.
RESULTS: During the period studied, 14,321 patients underwent open colectomy and 10,409 underwent laparoscopic colectomy. Factors that significantly influenced mortality included male gender [odds ratio (OR) 1.4, confidence interval (CI) 1.07-1.9]; age (OR 1.07, CI 1.05-1.08); comorbidities including dyspnea, ascites, congestive heart failure, dialysis, or disseminated cancer; and postoperative conditions including reintubation (OR 2.6, CI 1.6-4.0), renal failure (OR 3.8, CI 2.1-6.9), stroke (OR 6.44, CI 2.4-17.6), and septic shock (OR 13.1, CI 8.76-19.4). While laparoscopy was not independently associated with mortality, it was associated with decreased postoperative morbidity including reintubation (OR 0.74, CI 0.59-0.91), renal failure (OR 0.60, CI 0.4-0.91), septic shock (OR 0.74, CI 0.59-0.92), wound infection (OR 0.58, CI0.44-0.77), and pneumonia (OR 0.71, CI 0.59-0.86).
CONCLUSIONS: Based on this analysis, laparoscopy was associated with a decrease in 30-day postoperative morbidity for colectomy. However, after adjusting for preoperative comorbidities and postoperative morbidities, laparoscopy did not independently influence mortality after colectomy.

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Mesh:

Year:  2012        PMID: 22402957     DOI: 10.1007/s11605-012-1860-3

Source DB:  PubMed          Journal:  J Gastrointest Surg        ISSN: 1091-255X            Impact factor:   3.452


  13 in total

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3.  Determinants of long-term survival after major surgery and the adverse effect of postoperative complications.

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4.  Minimally invasive colon resection (laparoscopic colectomy).

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6.  Australian and New Zealand study comparing laparoscopic and open surgeries for colon cancer in adults: organization and conduct.

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7.  Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial.

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8.  A national comparison of laparoscopic vs. open colectomy using the National Surgical Quality Improvement Project data.

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9.  A comparison of laparoscopically assisted and open colectomy for colon cancer.

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10.  Laparoscopic-assisted vs. open colectomy for cancer: comparison of short-term outcomes from 121 hospitals.

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2.  Reduced perioperative death following laparoscopic colorectal resection: results of an international observational study.

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Review 7.  Meta-analysis of the impact of postoperative infective complications on oncological outcomes in colorectal cancer surgery.

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