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Literature DB >> 22344644

Relative catalytic efficiency of ldhL- and ldhD-encoded products is crucial for optical purity of lactic acid produced by lactobacillus strains.

Zhaojuan Zheng¹, Binbin Sheng, Cuiqing Ma, Haiwei Zhang, Chao Gao, Fei Su, Ping Xu.

Abstract

NAD-dependent l- and d-lactate dehydrogenases coexist in Lactobacillus genomes and may convert pyruvic acid into l-lactic acid and d-lactic acid, respectively. Our findings suggest that the relative catalytic efficiencies of ldhL- and ldhD-encoded products are crucial for the optical purity of lactic acid produced by Lactobacillus strains.

Entities: Chemical Gene

Mesh：

Substances：

Year: 2012 PMID： 22344644 PMCID： PMC3346457 DOI： 10.1128/AEM.00058-12

Source DB: PubMed Journal: Appl Environ Microbiol ISSN： 0099-2240 Impact factor: 4.792

21 in total

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Review 2. Bacterial lactate dehydrogenases.

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Journal: Microbiol Rev Date: 1980-03

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6. Lactic acid production from corn stover using mixed cultures of Lactobacillus rhamnosus and Lactobacillus brevis.

Authors: Fengjie Cui; Yebo Li; Caixia Wan
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9. Homo-D-lactic acid fermentation from arabinose by redirection of the phosphoketolase pathway to the pentose phosphate pathway in L-lactate dehydrogenase gene-deficient Lactobacillus plantarum.

Authors: Kenji Okano; Shogo Yoshida; Tsutomu Tanaka; Chiaki Ogino; Hideki Fukuda; Akihiko Kondo
Journal: Appl Environ Microbiol Date: 2009-06-05 Impact factor: 4.792

10. Efficient production of optically pure D-lactic acid from raw corn starch by using a genetically modified L-lactate dehydrogenase gene-deficient and alpha-amylase-secreting Lactobacillus plantarum strain.

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4. Major Role of NAD-Dependent Lactate Dehydrogenases in the Production of l-Lactic Acid with High Optical Purity by the Thermophile Bacillus coagulans.

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Journal: Appl Environ Microbiol Date: 2014-09-12 Impact factor: 4.792

10. Efficient production of (R)-2-hydroxy-4-phenylbutyric acid by using a coupled reconstructed D-lactate dehydrogenase and formate dehydrogenase system.

Authors: Binbin Sheng; Zhaojuan Zheng; Min Lv; Haiwei Zhang; Tong Qin; Chao Gao; Cuiqing Ma; Ping Xu
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