Literature DB >> 22330192

High-voltage electrical stimulation for the management of stage III and IV pressure ulcers among adults with spinal cord injury: demonstration of its utility for recalcitrant wounds below the level of injury.

Albert C Recio1, Cara E Felter, Anna Corrine Schneider, John W McDonald.   

Abstract

CONTEXT: patients with spinal cord injury (SCI) have many factors that are associated with pressure ulcer formation, including paralysis, loss of sensation, poor nutrition, anemia, and skin maceration related to incontinence. Treatment of these ulcers involves relieving pressure, improving nutrition and skin hygiene, treating infections, removing necrotic tissues, and applying the appropriate dressings. However, some cases are not responsive to the above treatment. Electrical stimulation (ES) is thought to enhance soft tissue healing through promotion of protein synthesis, inhibition of bacterial growth, facilitation of epithelial tissue migration, improvement of blood flow, and tensile strength. This data is mainly based on evidence from animal studies and very few rigorously controlled studies conducted in humans.
OBJECTIVE: To demonstrate the effectiveness of ES in the treatment of recalcitrant pressure ulcers.
METHODS: Retrospective case series describing the care of adults with SCI and recalcitrant pressure ulcers. ES was applied directly into the wound bed: 60 minutes per session, 3-5 times per week; with an intensity of 100 milliamperes and a frequency of 100 pulses per second. Polarity was negative initially and was switched weekly. The amplitude and wave form were maintained throughout.
RESULTS: The long-standing (11-14 months) pressure ulcers were completely healed after 7 to 22 weeks of treatment with high-voltage ES. CONCLUSION/CLINICAL RELEVANCE: This case series demonstrates the effectiveness of ES for enhanced healing of Stage III-IV ulcers otherwise unresponsive to standard wound care. Further study is needed to identify the most effective protocol for ES therapy in the treatment of recalcitrant pressure ulcers.

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Year:  2012        PMID: 22330192      PMCID: PMC3240918          DOI: 10.1179/2045772311Y.0000000044

Source DB:  PubMed          Journal:  J Spinal Cord Med        ISSN: 1079-0268            Impact factor:   1.985


  26 in total

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2.  Pressure ulcer prevention and treatment following spinal cord injury: a clinical practice guideline for health-care professionals.

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  8 in total

Review 1.  A systematic review of electrical stimulation for pressure ulcer prevention and treatment in people with spinal cord injuries.

Authors:  Liang Qin Liu; Julie Moody; Michael Traynor; Sue Dyson; Angela Gall
Journal:  J Spinal Cord Med       Date:  2014-06-26       Impact factor: 1.985

2.  Changes in FABP1 and gastrin receptor expression in the testes of rats that have undergone electrical injury.

Authors:  Xue-Fang Li; Quan-Yong Huang; Shui-Ping Liu
Journal:  Exp Ther Med       Date:  2015-03-23       Impact factor: 2.447

Review 3.  Electrical stimulation therapy for the treatment of pressure ulcers in individuals with spinal cord injury: a systematic review and meta-analysis.

Authors:  Deena Lala; Sandi J Spaulding; Shauna M Burke; Pamela E Houghton
Journal:  Int Wound J       Date:  2015-04-13       Impact factor: 3.315

4.  Monophasic Pulsed Microcurrent of 1-8 Hz Increases the Number of Human Dermal Fibroblasts.

Authors:  Yoshiyuki Yoshikawa; Masaharu Sugimoto; Mikiko Uemura; Masafumi Matsuo; Noriaki Maeshige; Emma Tabe Eko Niba; Hisato Shuntoh
Journal:  Prog Rehabil Med       Date:  2016-10-26

5.  Validation of the NIH Toolbox in Individuals with Neurologic Disorders.

Authors:  N E Carlozzi; S Goodnight; K B Casaletto; A Goldsmith; R K Heaton; A W K Wong; C M Baum; R Gershon; A W Heinemann; D S Tulsky
Journal:  Arch Clin Neuropsychol       Date:  2017-08-01       Impact factor: 2.813

6.  Electrical stimulation for treating pressure ulcers.

Authors:  Mohit Arora; Lisa A Harvey; Joanne V Glinsky; Lianne Nier; Lucija Lavrencic; Annette Kifley; Ian D Cameron
Journal:  Cochrane Database Syst Rev       Date:  2020-01-22

7.  Transplantation of erythropoietin gene-modified neural stem cells improves the repair of injured spinal cord.

Authors:  Min-Fei Wu; Shu-Quan Zhang; Rui Gu; Jia-Bei Liu; Ye Li; Qing-San Zhu
Journal:  Neural Regen Res       Date:  2015-09       Impact factor: 5.135

Review 8.  Efficacy of Bimodal High-Voltage Monopulsed Current in the Treatment of Pressure Ulcer: A Systematic Review.

Authors:  Zhiwei Zhang; Bojun Li; Zhichao Wang; Lina Wu; Lili Song; Yexiang Yao
Journal:  Iran J Public Health       Date:  2019-11       Impact factor: 1.429

  8 in total

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