| Literature DB >> 22297530 |
Yann R Chemla1, Douglas E Smith.
Abstract
Many double-stranded DNA bacteriophages and viruses use specialized ATP-driven molecular machines to package their genomes into tightly confined procapsid shells. Over the last decade, single-molecule approaches - and in particular, optical tweezers - have made key contributions to our understanding of this remarkable process. In this chapter, we review these advances and the insights they have provided on the packaging mechanisms of three bacteriophages: φ 29, λ, and T4.Entities:
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Year: 2012 PMID： 22297530 PMCID： PMC5933933 DOI： 10.1007/978-1-4614-0980-9_24
Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 2.622